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Bioinformatics (transgenic) PhD Projects, Programs & Scholarships

We have 9 Bioinformatics (transgenic) PhD Projects, Programs & Scholarships

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Showing 1 to 9 of 9
  Multimerisation of ELAV/Hu proteins – a key mechanism ensuring specificity for RNA recognition in health and disease
  Dr M Soller, Dr T Knowles
Applications accepted all year round

Funding Type

PhD Type

Aims. Determine the structure of the ELAV dodecameric complex bound to target RNA by cryoEM and functionally probe interaction interfaces in vitro and in vivo in transgenic Drosophila models for neurodegeneration and cancer.
  Can improved genetic understanding of grain weight help feed the world? (UAUYJ20DTP)
  Dr C Uauy
Application Deadline: 25 November 2019

Funding Type

PhD Type

Wheat provides 20% of the calories and protein consumed by humans. The world population will reach 9 billion by 2050, which requires food production to more than double.
  Regulation of autophagy in human embryonic stem cells and its therapeutic application in induced pluripotent stem cell-based disease models
  Dr S Sarkar
Applications accepted all year round

Funding Type

PhD Type

Project background. Regulation of proteostasis is critical for maintaining tissue homeostasis. Autophagy, a major intracellular degradation pathway essential for cellular and energy homeostasis, functions in the clearance of aggregation-prone proteins and damaged organelles.
  Live-imaging and genetic approaches to explore cross-talk between tissue damage, immune dysfunction and infection within novel animal models of cystic fibrosis
  Dr H Weavers, Prof E Mahenthiralingam, Dr D N Sheppard
Application Deadline: 25 November 2019

Funding Type

PhD Type

Cystic fibrosis (CF) is a genetic disorder driven by mutations in the CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) gene.
  Exploring the chromatin landscape in early development (WHEELERU20DTP)
  Dr G N Wheeler, Prof A E Munsterberg
Application Deadline: 25 November 2019

Funding Type

PhD Type

The Neural Crest and Placodes are groups of cells found only in vertebrates, specifically in the embryo. They originate at the neural border between the ectoderm and neuroectoderm.
  Understanding how altered GABA signalling in the brain’s master clock contributes to circadian rhythm disruption in Alzheimer’s disease. PhD in Medical Studies (MRC GW4 BioMed DTP)
  Dr M Belle
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr Mino Belle, Institute of Biomedical and Clinical Science, Medical School, University of Exeter. Dr James Hodge, Faculty of Life Sciences, University of Bristol.
  Understanding bone mass using collageneases and aggrecanases
  Prof G Bou-Gharios
Applications accepted all year round

Funding Type

PhD Type

Bone is not only essential for locomotion, support and protection but crucial for many aspects of animal and human health. Specifically, bone is a calcium/phosphorous reservoir, is integral to glucose metabolism, houses the hematopoietic system and cross-talks with renal and reproductive systems.
  Analysis of Heparin Binding Proteins and the Supramolecular Structure of Extracellular Matrix
  Prof D G Fernig, Prof C E Eyers
Applications accepted all year round

Funding Type

PhD Type

Changes in heparan sulfate structure and location have long been associated with Alzheimer’s disease, but the functional significance of this has remained elusive.
  Transcriptional battles in plant-pathogen interactions: understanding and re-wiring gene regulatory networks to enhance disease resistance
  Prof K Denby, Prof I A Graham
Application Deadline: 30 June 2020

Funding Type

PhD Type

The severity of plant disease is determined by a battle between pathogen virulence and host plant immunity – understanding this relationship is key to developing sustainable methods of pathogen control.
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