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Bioinformatics (antimicrobial) PhD Projects, Programs & Scholarships

We have 35 Bioinformatics (antimicrobial) PhD Projects, Programs & Scholarships

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  Genome mining of novel antimicrobial natural products from new bacterial strains
  Dr H Deng, Prof M Jaspars
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  Understanding and combatting antimicrobial resistance plasmids
  Dr M Buckner, Dr J Blair
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is a major crisis for human medicine. Globally, untreatable bacterial infections are rapidly increasing, leaving us with limited treatment options.
  EASTBIO Genomic epidemiology of bovine mastitis pathogens
  Dr G Paterson, Dr A Macrae, Prof R Fitzgerald
Application Deadline: 5 January 2020

Funding Type

PhD Type

Royal (Dick) School of Veterinary Studies / The Roslin Institute. Mastitis, inflammation of the mammary gland, is one of the most common and economically important diseases in dairy cattle.
  Identification and characterisation of barriers to antimicrobial resistance gene transfer
  Prof J Lindsay, Dr G Knight
Application Deadline: 1 January 2020

Funding Type

PhD Type

Antimicrobial resistance (AMR) is a great threat to the future of modern medicine (amr-review.org/Publications).
  GW4 BioMed MRC DTP PhD studentship: Defining the role of efflux in bacterial biofilm formation and antimicrobial resistance to develop new treatments for infection
  Dr B V Jones
Application Deadline: 25 November 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the ‘GW4 BioMed MRC Doctoral Training Partnership’ which is offering up to 18 studentships for entry in September 2020.
  MRC DiMeN Doctoral Training Partnership: Killing the unkillable. Developing bacterial capture compounds to identify new targets against antimicrobial resistant Staphylococcus aureus
  Dr R Corrigan, Dr D Williams
Application Deadline: 6 January 2020

Funding Type

PhD Type

The “superbug”, Methicillin resistant Staphylococcus aureus (MRSA) is a major threat to global health. Once inside a host, bacteria, like S.
  MRC DiMeN Doctoral Training Partnership: Killing the unkillable. Developing bacterial capture compounds to identify new targets against antimicrobial resistant Staphylococcus aureus
  Dr R Corrigan, Dr D Williams
Application Deadline: 6 January 2020

Funding Type

PhD Type

The “superbug”, Methicillin resistant Staphylococcus aureus (MRSA) is a major threat to global health. Once inside a host, bacteria, like S.
  MRC DiMeN Doctoral Training Partnership: Sharpening the blunted neutrophil response to antimicrobial resistant fungal infection
  Dr P Elks, Prof A Condliffe, Dr V See, Dr S Johnston
Application Deadline: 6 January 2020

Funding Type

PhD Type

Life-threatening invasive fungal infection is a major health problem in the immunocompromised, and emerging drug resistance is a major threat to global health.
  (BBSRC DTP) How ecological interactions shape mutation rates to antimicrobial resistance
  Research Group: Ecology and Evolution
  Dr C Knight, Prof A McBain, Dr P Paszek, Dr R Krašovec
Application Deadline: 31 January 2020

Funding Type

PhD Type

The chance that an organism mutates, for instance that a microbe mutates to resist an antibiotic, can depend on that organism’s environment.
  MRC Precision Medicine DTP: Deep impact – mining the meningococcal metagenome for antimicrobial resistance to provide public health intelligence data
  Research Group: Dental School
  Prof A Smith, Dr C Cameron
Application Deadline: 8 January 2020

Funding Type

PhD Type

Supervisors. Prof Andrew Smith. Dr Claire Cameron. Prof Martin Maiden. Project summary. This project will focus on meningococcal disease which is a severe and potentially fatal infection of the brain and blood stream with highest incidence in teenagers and young children.
  The maintenance of virulence and antimicrobial resistance in Shigella
  Prof C Tang
Application Deadline: 10 January 2020

Funding Type

PhD Type

Shigella spp are the main cause for dysentery worldwide, and emerged from commensal Escherichia coli following acquisition of a 210 kb virulence plasmid.
  Evolution of antimicrobial resistance
  Prof S Lovell
Applications accepted all year round

Funding Type

PhD Type

The increasing prevalence of anti-microbial resistance (AMR) is one of the key health challenges of the 21st centuryThe emergence of AMR is inherently an evolutionary problem.
  MRC DiMeN Doctoral Training Partnership: Design and Optimisation of Red/NIR Fluorescent Dyes for the Assessment of Antimicrobial Susceptibility
  Prof D Kell, Dr G Nixon
Application Deadline: 6 January 2020

Funding Type

PhD Type

The current anti-microbial resistance (AMR) crisis is well documented and the need for a very rapid antibiotic susceptibility test is key to preventing mis-diagnosis and subsequent mis-prescribing.
  MRC DiMeN Doctoral Training Partnership: How to kill a difficult superbug: understanding the evolution of antimicrobial resistance in Clostridioides difficile
  Dr R Fagan, Prof M Brockhurst
Application Deadline: 6 January 2020

Funding Type

PhD Type

Increasing resistance to antibiotics is one of the greatest health challenges facing humanity today. Clostridioides difficile is the primary cause of antibiotic-associated infections in UK hospitals and antibiotic-induced disruption of the gut microbiota is a prerequisite for infection.
  MRC DiMeN Doctoral Training Partnership: How to kill a difficult superbug: understanding the evolution of antimicrobial resistance in Clostridioides difficile
  Dr R Fagan, Prof M Brockhurst
Application Deadline: 6 January 2020

Funding Type

PhD Type

Increasing resistance to antibiotics is one of the greatest health challenges facing humanity today. Clostridioides difficile is the primary cause of antibiotic-associated infections in UK hospitals and antibiotic-induced disruption of the gut microbiota is a prerequisite for infection.
  Chemo-enzymatic Synthesis and Potential Applications of Novel Heterocyclic Alkaloids
  Dr H Deng, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  EASTBIO: Application of MinION Nanopore sequencing to understand the impact of environmental changes on sentinel indicators of ecosystem health
  Dr E Watson
Application Deadline: 5 January 2020

Funding Type

PhD Type

We are increasingly aware that human, veterinary and environmental health is intricately linked and farming and food production systems must not only be resilient to environmental changes and threats but the systems themselves must also perform with minimal environmental impact.
  SWBio DTP PhD project: Horizontal transfer of antiviral defences between bacterial species
  Dr T Taylor
Application Deadline: 2 December 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the South West Biosciences Doctoral Training Partnership (SWBio DTP).
  Evolution of multi-drug resistant gram negative clones
  Dr A McNally, Prof W Van Schaik
Applications accepted all year round

Funding Type

PhD Type

Increasing antibiotic resistance in bacterial infections is a serious threat to modern medicine, so understanding why some bacteria become resistant to multiple antibiotics whereas others do not is an important challenge for microbiologists, doctors and vets.
  The role of Efflux in Antibiotic Resistance of Clinically Relevant Pathogens
  Dr J Blair
Applications accepted all year round

Funding Type

PhD Type

Antibiotics underpin all of modern medicine; they are used to treat bacterial infections, and to prevent infections after surgery and in patients with a suppressed immune system such as those undergoing cancer chemotherapy or organ transplantation.
  A network approach to understanding the spread of antibiotic resistance. PhD in Biosciences (GW4 BioMed MRC DTP)
  Prof A Buckling
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Professor Angus Buckling, Department of Biosciences, College of Life and Environmental Sciences, University of Exeter.
  Development of metabolomics for understanding AMR in mixed infections
  Prof R Goodacre
Applications accepted all year round

Funding Type

PhD Type

Without correct antibiotic stewardship we could be cast back to a pre-infective era where we have run out of antibiotics to treat life-threatening infections.
  MRC DiMeN Doctoral Training Partnership: How does the human innate immune system kill the Streptococcus pneumoniae bacterium during infection?
  Dr A Fenton, Dr L Prince
Application Deadline: 6 January 2020

Funding Type

PhD Type

Background. The bacterium Streptococcus pneumoniae is a highly successful human pathogen and a leading cause of pneumonia, a disease responsible for millions of deaths every year.
  MRC DiMeN Doctoral Training Partnership: How does the human innate immune system kill the Streptococcus pneumoniae bacterium during infection?
  Dr A Fenton, Dr L Prince
Application Deadline: 6 January 2020

Funding Type

PhD Type

Background. The bacterium Streptococcus pneumoniae is a highly successful human pathogen and a leading cause of pneumonia, a disease responsible for millions of deaths every year.
  Comparative genomic analysis of variant features within the Neisseria spp.
  Dr L Snyder
Applications accepted all year round

Funding Type

PhD Type

The availability of rapid genome sequencing had generated an explosion of bacterial genome sequence data, much of which has not been fully explored and investigated.
  Investigation of a probiotic strain of Lactobacillus plantarum 2025 and the development of novel antibacterials
  Prof A Karlyshev
Applications accepted all year round

Funding Type

PhD Type

Background. The rise of multidrug resistant forms of microbial pathogens imposes a serious problem to public health worldwide. The rapid spread of antimicrobial resistance is associated with misuse of conventional antibiotics.
  (BBSRC DTP) Predictive Genotype-Phenotype-Fitness Mapping in E.coli
  Dr M Lagator, Dr J-M Schwartz, Dr P Day
Application Deadline: 31 January 2020

Funding Type

PhD Type

Genotype-phenotype-fitness mapping, or the connection between genetic mutations and their effects on organismal fitness, lies at the heart of understanding and predicting evolution.
  Combining Synthetic Biology and Modelling to Understand and Predict Evolution
  Dr M Lagator, Dr J-M Schwartz
Applications accepted all year round

Funding Type

PhD Type

Mutations, and their effects on organismal fitness, lie at the heart of understanding and predicting evolution. Because of its central role in determining evolutionary outcomes, much experimental and theoretical effort has been put into describing the fitness effects of mutations.
  Using synthetic biology to understand the evolution of antibiotic resistance
  Dr M Lagator, Dr C Knight
Applications accepted all year round

Funding Type

PhD Type

Imagine an architect, tasked with converting an old stadium into a building with a different function, without demolishing it.
  Maintaining the competitive edge through sRNA regulation
  Dr E Denham, Dr L A Cowley
Application Deadline: 8 December 2019

Funding Type

PhD Type

To survive in a competitive environment, a bacterium must be biologically fit.
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