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We have 25 Bioinformatics (brain) PhD Projects, Programmes & Scholarships

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Bioinformatics (brain) PhD Projects, Programmes & Scholarships

We have 25 Bioinformatics (brain) PhD Projects, Programmes & Scholarships

Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more

Short and long-term genetic and behavioural consequences of traumatic brain injury in fruit flies

General background . How many fingers am I holding up? What day of the week is it? Follow my finger? These three questions are designed to test your sensory, memory and motor neural abilities following an accident; all three systems are affected by a severe deceleration of your brain. Read more

Using Brain Computer Interface to Improve Cognitive Performance

Electroencephalogram (EEG) is a non-invasive technique commonly used to measure brain activity. In this project, we aim at using EEG Biofeedback (brain-computer interface (BCI)) for improving cognitive performance (e.g. Read more

Systemic infections accelerate tau spreading by promoting glial activation

Alzheimer’s disease (AD) is a neurodegenerative disease, with a complex biology. In this PhD project, we aim to explore the cellular and molecular mechanisms underlying tau pathology. Read more

Novel disease genes in brain development and decline

The Rare Disorder Genetics / Bicknell lab is interested in characterising novel genetic syndromes, with three core motivations. -the difference we can make to families with rare disorders, through providing them with more information. Read more

Manipulation of neuroimmune responses and behaviour by infectious agents

This project is available exclusively to self-funded students who wish to commence study for a PhD in the academic year 2023/24. The project focuses on how infectious agents modify the individuals that they infect and how neuroimmune responses to infection moderate behaviour changes in warm-blooded animals and humans. Read more

Faculty of Medicine, Masaryk University

The Biomedical Sciences doctoral degree programme has been created through the merging Medical Biology, Anatomy, Histology, Embryology, and Molecular Medicine, which has been designed in the CEITEC MU research centre to be a robust singular study programme consisting of three disciplines (Cell and Tissue Morphology, Biochemistry and Molecular Biology, and Molecular Medicine). Read more

The role of MicroRNAs in neurodegenerative diseases

We are seeking talented, motivated students with a passion for research in Neuroscience and Neurotrauma to join the team led by Dr Valentina Di Pietro (Dr Valentina Di Pietro - Institute of Inflammation and Ageing - University of Birmingham). Read more

Finding the cause of familial facial (Bell’s) palsy

The facial (VII) cranial nerve controls the muscles of facial expression, supplies taste sensation to parts of the tongue and controls a small muscle connected to the ear drum. Bell’s palsy is the clinical condition in which there is impaired function of the facial nerve, associated with facial muscle weakness. Read more

Epigenomic transcriptomic mechanisms underlying human neuropsychiatric and neurodegenerative diseases

This project aims to use high throughput sequencing technologies and molecular approaches to understand how RNA epitranscriptomic processes contribute to susceptibility to human disorders of the brain. Read more

(MRC DTP CASE) Multiomic evaluation of differential drug response in metastatic breast cancers

Breast cancers are the most common cancers in women. Estrogen Receptor (ER) plays a major role in breast cancer growth. To stop the cancer from growing further, clinically successful ER-targeting therapies like Fulvestrant, etc were developed. Read more

In silico modelling of endocannabinoid evolution

In the brain, the endocannabinoid (eCB) system maintains adequate neurotransmission (Lu and Mackie 2016). Indeed, the eCB system provides a negative feedback mechanism, preventing over-activation of synaptic transmission. Read more

PhD in stem cell modelling for neuropsychiatric disorders

This project provides a unique opportunity to explore the developmental origins of schizophrenia—a severe mental health disorder—using cutting-edge patient-derived stem cell models. Read more

Common genetic origins of visual and neurocognitive disorders

There is emerging evidence that apparently distinct neurodegenerative diseases have common genetic origins. For example, genes such as ARMS2 and HTRA1, which are fundamental to regulating neuronal health, are implicated in both dementia and diseases of the retina (particularly age-related macular degeneration). Read more

17 Graduate Teaching Assistants (GTAs) in the Institute of Industry and Innovation

The Institute of Industry and Innovation (I2RI) at Sheffield Hallam University intends to appoint up to 17 GTAs on 3.5 year fixed-term, full-time studentships from October 2024, with annual stipend at the living wage foundation rate (currently £19,722 in the academic year 23/24). Read more

Genetics: Investigating the molecular basis of optic nerve degeneration in glaucoma to try and develop a personalized medicine strategy for treatment

The optic nerve is a special sensory nerve that transmits visual impulses from the retina to the brain. Primary Open Angle Glaucoma (POAG) is a chronic, progressive optic neuropathy of multifactorial origin that affects 1 in 10 elderly individuals. Read more
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