Bioinformatics (cell culture) PhD Projects, Programmes & Scholarships

We have 29 Bioinformatics (cell culture) PhD Projects, Programmes & Scholarships

Nuclear and transcriptional dysregulations during cellular senescence

University of Leicester Molecular and Cell Biology

Cellular senescence, which is characterised by a proliferation arrest, is a driver of ageing (1). Several stresses can induce cellular senescence, including persistent DNA damage, telomere dysfunction, and oncogene activation. Read more

Supervisors: Dr MT Tellier, Dr Y Markaki

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Experimental and computational Cancer PhD: Overcoming osteosarcoma chemoresistance by characterizing and targeting cellular quiescence

University College London UCL Cancer Institute

Cancer is the leading cause of death in children and the second in young adults in England and Wales. Sarcomas, tumours that originate from connective tissues (bone, muscle, fat), account for around 15% of childhood cancers. Read more

Supervisors: Dr M Secrier, Dr L Cottone

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Exploring Myxobacteria as live antibiotics against pathogenic bacteria

Cardiff Metropolitan University Cardiff School of Sport and Health Sciences

Multi-drug resistant (MDR) bacteria have been identified as a global threat to humanity, limiting therapeutic options. The search for new antibiotics lags far behind the occurrence of MDR bacteria with no new antibiotics brought to the clinic for over 15 years. Read more

Supervisors: Dr P Livingstone, Dr S Maddocks

Year round applications PhD Research Project Self-Funded PhD Students Only

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Transcriptional kinases in cancer and developmental disorders

University of Leicester Molecular and Cell Biology

Cyclin-dependent kinases (CDKs) are protein kinases performing essential functions in regulation of cell cycle and transcription. Read more

Supervisor: Dr MT Tellier

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identifying critical pathways regulating autoimmunity in immuno-oncology and arthritis patients. Short title: IPADS (Immune PAthways for Drug Side-effects)

The University of Manchester Faculty of Biology, Medicine and Health

Inflammatory arthritis (IA) can result from non-autoimmune diseases (like crystal arthritis) and from autoimmune diseases like rheumatoid arthritis (RA) and spondyloarthropathies (inc. Read more

Supervisors: Dr S Viatte, Prof A Barton, Mr P Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Translational Medicine: Understanding the mechanism(s) of resistance to EPA to personalise therapy and improve outcome

University of Leeds Faculty of Medicine and Health

Advanced colorectal cancer (CRC) is the UK’s second most lethal cancer, with limited treatment options for unresectable metastatic tumours. Read more

Supervisors: Dr MA Volpato, Prof M Hull

Year round applications PhD Research Project Self-Funded PhD Students Only

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Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia susceptibility using model systems

University of Leeds Faculty of Medicine and Health

Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more

Supervisors: Prof P Hopkins, Dr M-A Shaw, Dr C Diggle

Year round applications PhD Research Project Self-Funded PhD Students Only

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The role of extracellular vesicles and intercellular signalling in inherited kidney cancer

Cardiff University Cardiff School of Medicine

This is a Self-Funded/Sponsored PhD opportunity. FUNDING REQUIRED. Full UK/EU or International Tuition Fees. UK Living Expenses. Bench Fees (£60,000 total). Read more

Supervisor: Dr E Dunlop

31 May 2024 PhD Research Project Self-Funded PhD Students Only

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Studying protein homeostasis in healthy and malignant stem cells

University of York York Biomedical Research Institute

This PhD will focus on studying the protein biology of healthy and malignant stem cells of the blood system. Read more

Supervisors: Dr W Grey, Prof D G Kent

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the genetic determinants of ultra-complex telomere fusion

Cardiff University Cardiff School of Medicine

We are seeking a motivated molecular biologist to study the mechanisms by which telomere dysfunction impacts cancer genomes. Read more

Supervisor: Prof D Baird

3 May 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

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EPSRC CDT in Bioprocess Engineering Leadership: Complex Biological Products Manufacture

University College London Department of Biochemical Engineering

Biological products and their manufacture are progressing to unparalleled levels of complexity. Examples include engineered biocatalysts, antibody-drug conjugates, multivalent vaccines and cellular therapies. Read more

Funded PhD Programme (UK Students Only) EPSRC Centre for Doctoral Training

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The Rhonski project: Examining Rho and Notch signalling in skin development and disease

St George’s, University of London Medical and Biomedical Education Institute

The skin provides a crucial protective layer between the human body and the outside world. Whilst the epidermis forms a barrier against infection, the inner dermis houses the blood vessels required to sustain the hair follicles and cells contained within both the epidermal and dermal layers. Read more

Supervisors: Dr LS Southgate, Dr A Chikh

26 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Control and inhibition of virus replication

University of Leeds Faculty of Biological Sciences

The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specifically Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets. Read more

Supervisor: Dr A.K Tuplin

Year round applications PhD Research Project Self-Funded PhD Students Only

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The use of life course epidemiology to support the experimental characterisation of genetic variation

University of Bristol Bristol Medical School

Project Background. There has been a rapid expansion in the generation of genetic sequence data over the last decade. Understanding the potential relevance of genetic mutations to human health remains challenging. Read more

Supervisors: Prof N Timpson, Dr L Corbin, Dr BL Lam

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Functional Mechanisms of Genetic Risk Factors for Immune-Related Disease

King’s College London School of Medicine

Who are we?. Read more

Supervisor: Prof T Vyse

Year round applications PhD Research Project Self-Funded PhD Students Only

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Mining data from National genomics Research Library to enable new gene discovery

University of Sheffield School of Medicine and Population Health

Whole Genome Sequencing (WGS) is a new genomic testing technology and process which became available through the NHS in April 2022. Read more

Supervisor: Dr M Balasubramanian

Year round applications PhD Research Project Self-Funded PhD Students Only

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Functional effects of variable number tandem repeat expansions in idiopathic pulmonary fibrosis

University of Leicester Department of Genetics and Genome Biology

Research Group: Human & Medical Genetics

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease characterized by the formation of scar tissue in the lungs. Read more

Supervisor: Prof E Hollox

Year round applications PhD Research Project Self-Funded PhD Students Only

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The role of MicroRNAs in neurodegenerative diseases

University of Birmingham Institute of Inflammation and Ageing

We are seeking talented, motivated students with a passion for research in Neuroscience and Neurotrauma to join the team led by Dr Valentina Di Pietro (Dr Valentina Di Pietro - Institute of Inflammation and Ageing - University of Birmingham). Read more

Supervisor: Dr V P Di Pietro

Year round applications PhD Research Project Self-Funded PhD Students Only

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Immunotherapy: Killing Cancer using Dead Virus

University of Leeds Faculty of Medicine and Health

It is now accepted that our immune systems can hold the key to treating otherwise incurable cancers. So-called “immunotherapy” is an increasingly common method of treating tumours, leading to impressive increases in patient responses. . Read more

Supervisors: Dr S Griffin, Dr A Samson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Repurposing drugs as new treatments for breast cancer

University of Leeds Faculty of Medicine and Health

Breast cancer (BC) is the most common cancer, with over 1 million new cases diagnosed worldwide each year. For some types of BC, hormonal treatments have been very effective but one particular BC subtype, triple negative breast cancer (TNBC), is highly aggressive and lacks a targeted therapy. Read more

Supervisors: Dr L Matthews, Dr P Meakin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic reprogramming of immune cells; novel mechanism for drug resistance in leukaemia

University of Leeds Faculty of Medicine and Health

Under pathogenic challenges, cells of the haematopoietic system become epigenetically reprogrammed and establish immune memory. Read more

Supervisor: Dr P Laslo

Year round applications PhD Research Project Self-Funded PhD Students Only

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Tissue Regeneration and Cancer MSc Research Programme

University of Glasgow

The Tissue Regeneration and Cancer MSc Research Programme at the University of Glasgow, will deliver high quality research, training and mentorship to excellent and ambitious students interested in cancer research, including- but not limited to- its intersection with stem cell biology, immunity, metabolism, development, regenerative biology, and behavioural science. Read more

Funded PhD Programme (Students Worldwide) Masters by Research

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Cardiac Harmony: Modelling Heart Beats with Stem Cells and Code

University of Liverpool Institute of Life Course and Medical Sciences

Despite significant advancements in cardiac research, heart disease remains a leading cause of mortality globally. Unexpected cardiac events can occur even in young, fit individuals engaged in routine activities. Read more

Supervisors: Prof R Barrett-Jolley, Dr R Oldershaw

Year round applications PhD Research Project Self-Funded PhD Students Only

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(MRC DTP CASE) Multiomic evaluation of differential drug response in metastatic breast cancers

The University of Manchester Faculty of Biology, Medicine and Health

Breast cancers are the most common cancers in women. Estrogen Receptor (ER) plays a major role in breast cancer growth. To stop the cancer from growing further, clinically successful ER-targeting therapies like Fulvestrant, etc were developed. Read more

Supervisors: Dr S Nagarajan, Dr HH Harrison, Prof R Clarke, Dr I Iqbal

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Immune regulation of lung repair, and long-term consequences of infection

University of Edinburgh School of Biological Sciences

This project is one of 14 four year PhD Studentships funded by Medical Research Scotland (MRS) (https://www.medicalresearchscotland.org.uk) to be delivered jointly by the named University and External Partner Organisation (EPO). Read more

Supervisors: Prof G Perona-Wright, Dr S Jenkins

14 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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NIHR Leeds BRC: Pre-clinical evaluation of novel regenerative medicine strategies for knee osteoarthritis

University of Leeds Faculty of Medicine and Health

Historically, articular cartilage was considered incapable of spontaneous repair. However, biomechanical correction in osteoarthritis (OA) using high tibial osteotomy or joint distraction demonstrated the remarkable joint to regeneration by “merely” correcting joint alignment. Read more

Supervisors: Prof H Pandit, Prof D McGonagle

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Transcriptome biomarkers and mechanisms of chemoresistance

Queen Mary University of London Institute of Dentistry

Project Summary. This project aims to identify biomarkers linked to the most potent multimodal anticancer therapy with the least toxicity to counteract hemoresistance in head and neck squamous cell carcinoma (HNSCC). Read more

Supervisor: Dr M T Teh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Exosome biogenesis and organelle trafficking in neurodegeneration.

University of Nottingham School of Life Sciences

Scientific summary. Intracellular transport pathways are fundamental for cell structure and function. Due to their longevity, complex morphology (long axonal and dendritic extensions) and requirement to maintain synaptic transmission, neurons are heavily dependent upon intracellular transport. Read more

Supervisors: Dr A Hume, Dr DS Scott, Dr F Dajas-Bailador

Year round applications PhD Research Project Self-Funded PhD Students Only

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Examining the mechanisms that cause cardiovascular disease by studying the heart or adipose tissue

University of Reading Department of Biomedical Sciences

Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more

Supervisor: Dr S Boateng

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 29 Bioinformatics (cell culture) PhD Projects, Programmes & Scholarships

Bioinformatics (cell culture) PhD Projects, Programmes & Scholarships

We have 29 Bioinformatics (cell culture) PhD Projects, Programmes & Scholarships

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