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Bioinformatics (information studies) PhD Projects, Programs & Scholarships

We have 133 Bioinformatics (information studies) PhD Projects, Programs & Scholarships

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Showing 1 to 30 of 133
  Optimising the efficiency of systematic reviews of diagnostic test accuracy studies
  Dr P Whiting
Application Deadline: 25 November 2019

Funding Type

PhD Type

Diagnostic test accuracy (DTA) systematic reviews (SR) provide the most reliable form of evidence for decision makers on the accuracy of a diagnostic test.(1) A full SR is extremely resource intensive, often taking months or years to complete.
  SWBio DTP PhD project: Ancestral functions of genes regulated by imprinting in mammals
  Prof A Ward, Prof R N Kelsh, Prof J Wolf
Application Deadline: 2 December 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the South West Biosciences Doctoral Training Partnership (SWBio DTP).
  Developing, evaluating and applying methods for robustly handling dropout in cohort studies
  Dr R Hughes
Application Deadline: 25 November 2019

Funding Type

PhD Type

The project. Cohort studies, (e.g., UK Biobank) are used to inform about clinical practice but face problems of missing data arising through non-response and dropout.
  Genetic approaches to understand the complex links between obesity, socio-cultural factors and mental health. PhD in Medical Studies (MRC GW4 BioMed DTP)
  Dr J Tyrrell
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr Jess Tyrrell, College of Medicine and Health, Institute of Biomedical and Clinical Science, University of Exeter.
  Bioinformatics studies of protein structures, functions and their interactions
  Dr L J McGuffin
Applications accepted all year round

Funding Type

PhD Type

The computational study of protein structures, functions and their interactions is fundamental to our understanding of disease.
  Understanding how the NuRD complex regulates 3D genome organization using a combination of single-molecule super-resolution imaging and single cell biology
  Prof E D Laue
Applications accepted all year round

Funding Type

PhD Type

The spatial organisation of the genome is known to play an important role in regulating RNA transcription to effect cell-type-specific gene expression programs, and to control the differentiation of embryonic stem (ES) cells.
  Precision Medicine DTP – Integration of single-cell RNA sequencing data from human and murine kidney disease to identify novel therapeutic targets
  Research Group: Centre for Cardiovascular Science
  Dr BC Conway, Dr T Chandra, Dr D Ferenbach
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Chronic kidney disease (CKD) is a major risk factor for cardiovascular disease and for end-stage kidney disease (ESRD), at which point patients require dialysis or transplantation.
  Precision Medicine DTP - Synthetic chromosomes to understand genome instability
  Research Group: MRC Human Genetics Unit
  Prof N Gilbert, Prof A Marston
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Genomic instability in cancer has been known for many years; the advent of genomic analyses in the late 1990’s enabled these changes to be characterized in detail.
  Developing GWAS approaches to decipher the drivers of Bordetella pertussis adaptation during re-emergence
  Dr A Preston
Application Deadline: 12 January 2020

Funding Type

PhD Type

Genome rearrangement, the reordering of genes along the chromosome, is widespread among bacteria. It is thought to affect bacterial phenotype (behaviour) and contribute to their evolution and adaptation.
  Development of image analysis methods and software to study musculoskeletal diseases using artificial intelligence (AI)
  Dr Claudia Lindner, Prof T Cootes
Applications accepted all year round

Funding Type

PhD Type

Musculoskeletal (MSK) diseases affect an increasing number of the population globally. In the UK, on average 3 in 10 people are affected, which increases to 1 in 2 in the age group 65+.
  A PhD applying machine learning techniques to Next Generation Sequencing Big Data to improve Prostate Cancer patient outcome. (BrewerD-CooperCU19SF)
  Dr D Brewer, Prof C Cooper
Application Deadline: 31 May 2020

Funding Type

PhD Type

Prostate cancer (PCa) is the second most common cancer in men worldwide and an estimated 307,000 men annually die from PCa worldwide.
  EASTBIO Developing Ovine Immune ‘Omics for sheep genomic improvement
  Dr E Clark, Dr M Coffey
Application Deadline: 5 January 2020

Funding Type

PhD Type

Royal (Dick) School of Veterinary Studies / The Roslin Institute. The aim of this project is to use an ‘omics approach to identify genetic variants that can potentially be used in development of a next generation of productive sheep breeds or crossbreeds resilient to the on-going effects of changing disease pressures.
  4-year PhD in Genetic Epidemiology: The intergenerational transmission of health
  Dr N Davies
Application Deadline: 13 December 2019

Funding Type

PhD Type

We are offering an exciting 4-year PhD studentship* for candidates interested in discovering how health and wellbeing are transmitted across generations within families.
  MRC DTP 4 Year PhD Programme: Mendelian Randomisation Approaches to defining the Underlying risk factors for the Dementias.
  Dr A Doney, Dr W Meng
Application Deadline: 11 January 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  Precision Medicine DTP - Modelling Sex Dependent Differences in Human Liver Disease using Stem Cell Derived Models and Organ on a Chip Devices
  Research Group: MRC Centre for Regenerative Medicine
  Dr D Hay, Prof P Saunders
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Metabolic syndrome is a cluster of conditions, which include increased blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels.
  Precision Medicine DTP - Stromal transcriptomic signatures in prostate cancer metastasis and hormone therapy resistance
  Research Group: MRC Centre for Reproductive Health
  Dr B Qian, Prof H Y Leung, Dr A Sims, Prof P Wiklund
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. A tremendous amount of cancer ‘-omics’ data have been generated with the intention to stratify patients for personalized diagnosis and treatment.
  Precision Medicine DTP - The role of transcription factors and the signaling environment in commitment of cells into the germline
  Research Group: Institute of Stem Cell Research
  Prof I Chambers, Dr T Chandra
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. In mammals, specification of the germline occurs shortly after implantation. Understanding how germ cells become specified is important both to inform the treatment of human infertility, for example through in-vitro spermatogenesis, and for the wider field of regenerative medicine.
  Decoding the genetic architecture of inflammatory arthritis at the single-cell level #RACE5
  Dr S Sansom, Prof P Bowness, Dr L Jostins-Dean, Prof K Raza
Application Deadline: 10 January 2020

Funding Type

PhD Type

Supervisors. Dr Stephen Sansom, Professor Paul Bowness, Dr Luke Jostins-Dean and Professor Karim Raza. Genome wide association studies (GWAS) of inflammatory arthritis have now revealed hundreds of genetic variants that are linked to different forms of inflammatory arthritis.
  Adapting to climate change: transgenerational acclimation as a mechanism of rapid evolution
  Dr M Truebano Garcia, Dr P Cotton
Application Deadline: 7 January 2020

Funding Type

PhD Type

In the context of climate change, it is imperative to determine to what extent species have the capacity to persist in a warmer environment.
  The epigenetics of Parkinson’s disease: searching for novel drug targets. PhD in Medical Studies (MRC GW4 BioMed DTP)
  Dr A Migdalska-Richards
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr Anna Migdalska-Richards, Institute of Clinical Biosciences, College of Medicine and Health, University of Exeter.
  The influence of JAKMIP1, a key risk gene for autism, on neural circuit function. PhD in Medical Studies (MRC GW4 BioMed DTP)
  Dr A Oguro-Ando
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr Asami Oguro-Ando, The Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter.
  Understanding how altered GABA signalling in the brain’s master clock contributes to circadian rhythm disruption in Alzheimer’s disease. PhD in Medical Studies (MRC GW4 BioMed DTP)
  Dr M Belle
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr Mino Belle, Institute of Biomedical and Clinical Science, Medical School, University of Exeter. Dr James Hodge, Faculty of Life Sciences, University of Bristol.
  Investigation of a probiotic strain of Lactobacillus plantarum 2025 and the development of novel antibacterials
  Prof A Karlyshev
Applications accepted all year round

Funding Type

PhD Type

Background. The rise of multidrug resistant forms of microbial pathogens imposes a serious problem to public health worldwide. The rapid spread of antimicrobial resistance is associated with misuse of conventional antibiotics.
  GW4 BioMed MRC DTP PhD studentship: Cannabis, Tobacco and Psychiatric Disease: Isolating their Relationship by Comparing Data from Countries that Smoke Cannabis with and without Tobacco
  Dr G Taylor
Application Deadline: 25 November 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the ‘GW4 BioMed MRC Doctoral Training Partnership’ which is offering up to 18 studentships for entry in September 2020.
  Comparative studies of wound and cancer inflammation in plants and animals
  Prof P B Martin
Applications accepted all year round

Funding Type

PhD Type

All organisms need to be able to repair wounds. A key aspect of this is combating the potential for infection when barrier layers are breached by tissue damage.
  Genetic Architecture of Inherited Cardiomyopathy
  Prof M Farrall, Dr AG Goel, Prof H Watkins
Application Deadline: 10 January 2020

Funding Type

PhD Type

Studying genetic variation in cardiomyopathy and coronary artery disease across the entire allele frequency spectrum in order to identify causative genes and susceptibility loci.
  MRC DiMeN Doctoral Training Partnership: Using wearable technology to identify activity and sleep patterns in inpatients with delirium and Parkinson’s disease
  Dr R Lawson, Dr S Del Din, Dr A Yarnall, Dr J Shi
Application Deadline: 6 January 2020

Funding Type

PhD Type

We are offering an enthusiastic and motivated PhD student the exciting opportunity to join our international renowned team.
  SWBio DTP PhD project: Horizontal transfer of antiviral defences between bacterial species
  Dr T Taylor
Application Deadline: 2 December 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the South West Biosciences Doctoral Training Partnership (SWBio DTP).
  SWBio DTP PhD project: Role of microRNAs in regulating sex differences in stress responsive neurocircuitry across the lifespan
  Prof M Lindsay, Dr S J Bailey
Application Deadline: 2 December 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the South West Biosciences Doctoral Training Partnership (SWBio DTP).
  Precision Medicine DTP - A personalised automatic approach for assessing and modelling the brain deep tissue waste drainage related structures
  Research Group: Centre for Clinical Brain Sciences
  Dr M Valdes Hernandez, Prof J Wardlaw, Dr M Bernabeu
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Previous experiments (Kress 2014) have suggested that brain features known as perivascular spaces play an important role in the clearance of metabolic waste from the brain tissue.
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