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Bioinformatics (php) PhD Projects, Programs & Scholarships

We have 65 Bioinformatics (php) PhD Projects, Programs & Scholarships

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  EASTBIO: Gut microbiota mediates distinct metabolic effects through dietary fibre fermentation.
  Dr A Ross, Prof P Morgan
Application Deadline: 5 January 2020

Funding Type

PhD Type

Supervisors. Dr Alexander Ross (University of Aberdeen). https://www.abdn.ac.uk/rowett/research/alexander-ross.php. Professor Peter Morgan (University of Aberdeen).
  Getting to grips with severe asthma - a whole population approach using routinely acquired data.
  Prof S Turner, Dr D Miller
Applications accepted all year round

Funding Type

PhD Type

There are 500,000 people in Scotland who have asthma. Asthma symptoms range from mild through moderate to severe. Severe asthma is not common but since it is associated with morbidity and mortality, severe asthma is a considerable burden to patients, society and the NHS.
  Using CRISPR genome editing to determine the effects of obesity and hypertension associated polymorphisms
  Dr A MacKenzie, Prof M Delibegovic
Applications accepted all year round

Funding Type

PhD Type

Introduction. There is now little doubt that morbid conditions such as obesity, cardiovascular disease and diabetes are mechanistically linked.
  QUADRAT DTP: Environmental ancient DNA analysis of Lateglacial and Early Holocene contexts in Ireland and Scotland
  Dr L Girdland Flink, Dr G Plunkett
Application Deadline: 22 January 2020

Funding Type

PhD Type

This project aims to refine our understanding of Lateglacial and Early Holocene biodiversity and ecosystems in Scotland and Ireland using ancient DNA extracted from ancient sediments (sedimentary ancient DNA, or sedaDNA).
  EASTBIO: Dehalogenases from the brown algal genome model Ectocarpus siliculosus
  Prof F Kuepper, Dr H Deng, Prof M Jaspars
Application Deadline: 5 January 2020

Funding Type

PhD Type

Supervisors. Professor Frithjof Kuepper (University of Aberdeen). http://www.abdn.ac.uk/oceanlab/research/frithjof-kuepper.php. Dr Hai Deng (University of Aberdeen).
  KESS2 Scholarship: The Biodiversity and Ecosystem Dynamics of higher delta-plain carboniferous swamps.
  Dr A. Papadopulos
Application Deadline: 20 December 2019

Funding Type

PhD Type

This a unique opportunity to conduct evolutionary and paleoecological research on one of the UK’s most well-preserved fossil forests at Brymbo, Wrexham.
  Investigation of a probiotic strain of Lactobacillus plantarum 2025 and the development of novel antibacterials
  Prof A Karlyshev
Applications accepted all year round

Funding Type

PhD Type

Background. The rise of multidrug resistant forms of microbial pathogens imposes a serious problem to public health worldwide. The rapid spread of antimicrobial resistance is associated with misuse of conventional antibiotics.
  Archaeal polyphosphate cycling: novel enzymes to drive new technologies
  Dr J Chin, Prof J Mcgrath
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Phosphorus is a globally important resource used particularly by the agricultural industry in fertiliser, enabling the growth of enough crops to feed the world’s increasing population.
  Exposing drivers for parasite growth and virulence at the single cell level
  Prof A Maule, Dr P McVeigh, Dr N Marks
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Parasites infect one third of the human population, causing staggering levels of morbidity. They also blight food production systems by undermining plant and animal health globally.
  Gene mining useful biocatalysts from paleosols
  Prof C Allen, Dr C Law
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Paleosols are often sediments that are relatively unaffected by the Anthropocene. While there is much research on the microbial community structure found in urban and agricultural soils, these relatively undisturbed soils are very different in a geological and physical context.
  Genome scale evolution of biofilm contained Klebsiella pneumoniae in response to sub-lethal antibacterial stress exposure - development of novel biomarkers for near-patient testing
  Prof S Fanning, Prof B Gilmore
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Klebsiella pneumoniae is an opportunistic pathogenic bacterium found in several niches, being often encountered in a biofilm.
  How does biodiversity contribute to multiple forms of stability in stressed marine invertebrate communities?
  Prof M Emmerson, Dr S Helyar, Dr P Caplat
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. We now know that biodiversity is important because different species simultaneously contribute to multiple ecosystem processes through time and space (Gamfeldt et al.
  Microbial interactions in unique chemosynthetic ecosystems –an integrated ‘Omic approach
  Dr D Kumaresan, Prof J Mcgrath, Dr R Doherty
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Despite the lack of photosynthetically-fixed carbon, the Movile Cave ecosystem hosts a diverse range of invertebrates.
  Sustainable Wildlife Management: Socio-Economics Drivers & Implications of Conservation
  Dr M Bozzola, Dr J Houghton
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Wildlife conservation of endangered species has been a growing concern all over the world, as human populations grow and their need for space and resources multiplies.
  Temperature regulation of non-coding RNA and crop - rhizosphere interactions
  Dr J Dalzell, Dr FL Liu
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Crop plants manipulate rhizosphere interactions through the release of root exudates. Whilst root exudates can attract beneficial microbes, they are also exploited by pathogens and plant parasitic nematodes (PPNs).
  The relative importance of different species traits for predicting invasion success and impact - a sensitivity analysis approach
  Dr K Farnsworth, Dr I Capellini
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. The overall aim of this project is to develop a better understanding of the factors making a potential invader most dangerous.
  The rice paddy microbiome and its impact on plant mineral nutrition
  Dr C Meharg, Prof A Meharg
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Rice is an important cereal crop.
  What drives early-life “programming” in the rumen microbiome?
  Prof C Creevey, Dr K Theodoridou, Prof S Huws
Application Deadline: 16 December 2019

Funding Type

PhD Type

Project details. Manipulation of microorganisms in the rumen of cattle, sheep and deer is a promising strategy for lowering their environmental impact while increasing their efficiency.
  Precision Medicine DTP - A personalised automatic approach for assessing and modelling the brain deep tissue waste drainage related structures
  Research Group: Centre for Clinical Brain Sciences
  Dr M Valdes Hernandez, Prof J Wardlaw, Dr M Bernabeu
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Previous experiments (Kress 2014) have suggested that brain features known as perivascular spaces play an important role in the clearance of metabolic waste from the brain tissue.
  Precision Medicine DTP - An integrated computational-experimental approach to identify and optimise combination drug therapy for non-alcoholic fatty liver disease (NAFLD)
  Research Group: Centre for Inflammation Research
  Prof J Fallowfield, Dr F Menolascina, Prof J Plevris
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Non-alcoholic fatty liver disease (NAFLD) is the commonest cause of chronic liver disease (CLD), affecting 1 in 4 people worldwide.
  Precision Medicine DTP - Analyzing network formation during brain tumour initiation
  Dr D Sieger, Prof P Uhlén
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. High grade brain tumours (HGBTs) represent a complex and devastating disease and are posing an unmet clinical need. These tumours resist multi-modal therapies and survival times are only 15 months on average.
  Precision Medicine DTP - Comprehensive study of miRNAs biogenesis in human cancer
  Dr G Michlewski, Dr C Kutter
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. MicroRNAs (miRNAs) are short non-coding RNAs ~22 nt in length that function as important regulators of gene expression1.
  Precision Medicine DTP - Delirium as an acute brain injury in hospital inpatients: can clinical features and biomarkers predict outcomes?
  Prof A Maclullich, Dr D McAllister, Dr S Shenkin
Application Deadline: 8 January 2020

Funding Type

PhD Type

Additional Supervisor - Dr Matthew Reed. Background. Delirium is a severe medical emergency that is triggered by acute medical illness, drugs, trauma or surgery.
  Precision Medicine DTP - Developing data science approaches to improve paediatric critical care patient flows and its related health economics benefits in Scotland
  Research Group: Centre for Medical Informatics
  Dr T Lo, Dr A Manataki, Dr L Moss, Dr A Neilson
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Paediatric critical care (PCC) is a highly valued specialist service that saves infants and children’s life. Over the past decade, the demand of PCC beds exceeds the expected population growth in the UK.
  Precision Medicine DTP – Development of clinically relevant models of undifferentiated pleomorphic sarcoma using a genetic screening approach
  Research Group: Edinburgh Cancer Research Centre
  Prof V Brunton, Dr L Boulter, Dr M Taylor, Prof D M Salter
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Sarcomas are relatively uncommon cancers thought to arise from pluripotent mesenchymal stem cells. Undifferentiated pleomorphic soft tissue sarcoma (UPS), though one of the commonest sarcoma subtypes encountered, exemplify the limitations of historical progress in sarcoma therapy.
  Precision Medicine DTP - Genomic analysis of the impact of sexual recombination on the segregation of virulence genes in African trypanosomes
  Research Group: The Roslin Institute
  Dr L Morrison, Dr A MacLeod, Dr J Prendergast
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. African trypanosomes are vector-borne protozoa that cause serious human and animal disease across sub-Saharan Africa.
  Precision Medicine DTP - Harnessing plasticity to repair spinal cord injury
  Dr T Becker, Prof C G Becker, Prof A El Manira
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. After a spinal cord injury in the zebrafish, lost neurons are replaced and axonal connections re-established (Tsarouchas et al., 2018).
  Precision Medicine DTP - How do IFITM proteins regulate the Interferon Related DNA-damage Resistance Signature (IRDS) and clinical outcomes in cancers of high unmet clinical need?
  Dr R Sloan, Prof K Ball, Dr S Wilson
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Interferon Induced Transmembrane proteins (IFITMs) are a family of innate immune membrane proteins that can inhibit viral infection at cell entry (e.g.
  Precision Medicine DTP - Identification of biomarkers of typical and atypical depression
  Research Group: Centre of Genomic and Experimental Medicine
  Dr P Thomson, Dr R Strawbridge
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Major depressive disorder (MDD) is a highly polygenic disorder with hundreds of common risk variants identified through genome-wide association studies of large samples.
  Precision Medicine DTP - Identifying Pathogenic B cells in Rheumatoid Arthritis
  Research Group: Centre for Inflammation Research
  Dr M Gray, Prof C Goodyear, Dr G Cowan
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Rheumatoid Arthritis (RA) is the commonest, most destructive, autoimmune inflammatory arthritis, causing chronic pain, fatigue, depression and disability.
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