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Bioinformatics (metabolism) PhD Projects, Programmes & Scholarships
We have 24 Bioinformatics (metabolism) PhD Projects, Programmes & Scholarships
We have 24 Bioinformatics (metabolism) PhD Projects, Programmes & Scholarships
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Mechanistic computational modelling of human glioblastoma metabolism
Glioblastoma is the most common and the most lethal malignant brain tumor. In vitro cell culture of glioma cells is essential for the discovery and development of novel anticancer treatments. Read more
Understanding metabolism in the blood cancer multiple myeloma and its precursor condition MGUS
Applications will be reviewed until a suitable candidate is appointed and funding is available. Read more
Engineering more water-use efficient crops: functional genomics of CO2 fixation during Crassulacean acid metabolism
The world is getting hotter and drier due to climate change, and the human population is growing rapidly to the extent that it has been predicted that we will need to increase crop yields by 50 - 70 % by 2050 in order to feed the predicted 9 - 10 billion people. Read more
Investigate the novel therapeutic potential for treating heart failure in diabetes.
Heart failure is the most common cause of mortality in diabetes patients, but current diabetes therapies have a limited impact on the incidence of heart failure in diabetic populations. Read more
Transferring mass spectrometry from the laboratory to the clinic for metabolic biomarkers in human health and disease
Please note, applications will be reviewed until a suitable candidate is appointed and funding is available. Read more
Enhancing clinical metabolomic studies through improved laboratory and bioinformatics tools
Applications will be reviewed until a suitable candidate is appointed and funding is available. Metabolites play many important roles in humans including in metabolism of food, synthesis of proteins and DNA, in signalling and regulation of biochemical mechanisms and in the development and progression of diseases. Read more
Self-funded project: Uncovering the biological roles of recently discovered carbohydrate-active enzymes in green microalgae.
Photosynthetic microalgae are microbes that have colonized every habitat on Earth, and are paramount in fueling the global ocean biological carbon pump. Read more
Evaluation of MCT1s role in chromatin remodelling and metabolomics changes involved in cancer progression
Monocarboxylate transporter 1 (MCT1) is a transmembrane protein involved in cell metabolism and mediates transport of monocarboxylates (such as pyruvate {a metabolic substrate} and lactate {a metabolic by product}) in and out of the cell. Read more
Four-year PhD to assess the development of mother-offspring multi’omic “handprints” that predict child phenotypes
Strong evidence now supports a crucial role for early metabolomes in programming lifelong health. This project based in the NIHR Southampton Biomedical Research Centre provides an important opportunity to inform new interventions to promote healthy lifecourse trajectories in the next generation. Read more
Stress responses in crops and sustainable production of chemicals and biomass
The project aims at elucidating several aspects of the control of plant stress responses to identify environmentally friendly forms of plant protectants and phytopharmaceuticals, leading to enhanced crop yields and solutions for animals and human health. Read more
EN & MN Lindsay Scholarship: Developing in silico approaches for compound optimisation in Drug Discovery: targeting polypharmacology using Artifical Intelligence
We invite applications for a fully funded four-year EN & MN Lindsay Endowed PhD studentship in developing in silico approaches for compound optimisation in drug discovery at the University of Dundee, United Kingdom. Read more
Last chance to apply
Nitrate supplementation as an alternative to antiseptic mouthwash and a method to reduce the burden of antimicrobial resistance (VP2228)
This project builds upon our pioneering research which shows that nitrate, a compound found in green leafy vegetables, can substantially improve key markers of periodontitis (gum disease) and cardiovascular health. Read more
Understanding the molecular basis of drug resistance in myeloid cancers
Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory. Read more
Mitochondria biogenesis and stress responses in health and disease
Maintenance of functional mitochondria is essential for life and an important therapeutic target in several diseases, including age-related neurodegenerative diseases. Read more
MSc by Research: Genetic interactions and novel genes that regulate lignin biosynthesis and straw quality in barley
Lignin is a major component of plant cell walls, and has a significant influence on the digestibility and uses of plant biomass. The lignin biosynthesis pathway has been one of the most intensively studied plant metabolic pathways over the past two decades. Read more
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