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Bioinformatics (metabolism) PhD Projects, Programmes & Scholarships

We have 26 Bioinformatics (metabolism) PhD Projects, Programmes & Scholarships

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We have 26 Bioinformatics (metabolism) PhD Projects, Programmes & Scholarships

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Mechanistic computational modelling of human glioblastoma metabolism

Glioblastoma is the most common and the most lethal malignant brain tumor. In vitro cell culture of glioma cells is essential for the discovery and development of novel anticancer treatments. Read more

Engineering more water-use efficient crops: functional genomics of CO2 fixation during Crassulacean acid metabolism

The world is getting hotter and drier due to climate change, and the human population is growing rapidly to the extent that it has been predicted that we will need to increase crop yields by 50 - 70 % by 2050 in order to feed the predicted 9 - 10 billion people. Read more
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Roles for “persister” cells in drug treatment failure in Leishmania

It has become clear in recent years that bacterial pathogens, within their mammalian hosts, can enter a quiescent state where metabolism is partially switched… Read more

Enhancing clinical metabolomic studies through improved laboratory and bioinformatics tools

Applications will be reviewed until a suitable candidate is appointed and funding is available. Metabolites play many important roles in humans including in metabolism of food, synthesis of proteins and DNA, in signalling and regulation of biochemical mechanisms and in the development and progression of diseases. Read more

Evaluation of MCT1s role in chromatin remodelling and metabolomics changes involved in cancer progression

Monocarboxylate transporter 1 (MCT1) is a transmembrane protein involved in cell metabolism and mediates transport of monocarboxylates (such as pyruvate {a metabolic substrate} and lactate {a metabolic by product}) in and out of the cell. Read more
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Investigating novel molecular regulators of the brown adipocyte programme

Brown adipose tissue is an enigmatic tissue that plays an important role in energy metabolism. The increasing prevalence of obesity-related disorders has led to a growing need for therapeutic strategies to reverse diet-induced weight gain. Read more

Project at Queen's University Belfast - Nutritional programming in replacement dairy heifers: Future-proofing herd performance, health and behaviour

Project background. The lifetime performance of a dairy calf is impacted by its health, nutrition and environment, with a sub optimal position in any of these factors affecting the animal’s ability to achieve its genetic potential. Read more

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