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University of Leeds Bioinformatics PhD Projects, Programs & Scholarships

We have 7 University of Leeds Bioinformatics PhD Projects, Programs & Scholarships

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  Control and inhibition of virus replication
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A.K Tuplin
Applications accepted all year round

Funding Type

PhD Type


The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specificaly Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets.
  Genetic studies of corneal endothelial dystrophies and development of alternative treatment options
  Dr M Ali
Applications accepted all year round

Funding Type

PhD Type

The cornea is the protective front part of the eye that provides most of the eyes focusing power. The endothelium is a single-cell layer on the inside of the cornea that maintains fluid balance and is required for corneal transparency.
  Genome and transcriptome sequencing and functional analysis to find new mutation types in patients with inherited blindness
  Prof C Inglehearn
Applications accepted all year round

Funding Type

PhD Type

Human inherited retinal dystrophies (IRDs) result from mutations in over 200 different genes, many of them first implicated by the Leeds Vision Research Group (eg Panagiotou E et al 2017, AJHG 100:960-968; El-Asrag M et al 2015, 96:948-54).
  How human teeth form and how that process fails in the inherited condition amelogenesis imperfecta
  Prof C Inglehearn
Applications accepted all year round

Funding Type

PhD Type

Amelogenesis is the process of enamel formation and is essential for the development of functional teeth. Amelogenesis imperfecta (AI) is a failure of that process.
  Predicting therapy responses in psoriasis
  Dr M Wittmann
Application Deadline: 6 June 2020

Funding Type

PhD Type

Treatment options for inflammatory skin diseases such as psoriasis have greatly improved over the last decade. However, our current inability to predict who will respond best to which treatment causes frustration for both clinicians and patients.
  Using next-generation sequencing and CRISPR-Cas9 gene editing to investigate penetrance and phenotypic variation in inherited eye disease
  Dr C Toomes
Applications accepted all year round

Funding Type

PhD Type

Human inherited retinal diseases (IRDs) result from mutations in over 250 different genes, many of them implicated by the Leeds Vision Research Group (eg Panagiotou et al 2017, AJHG 100:960-968; El-Asrag et al 2015, 96:948-54).
  Oncogenic reprogramming of immune cells, a novel mechanism of drug-resistance.
  Dr P Laslo
Applications accepted all year round

Funding Type

PhD Type

Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory.
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