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University of Manchester Bioinformatics PhD Projects, Programs & Scholarships

We have 57 University of Manchester Bioinformatics PhD Projects, Programs & Scholarships

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Showing 1 to 10 of 57
  (BBSRC DTP CASE) Applying – omics methods to map the circadian matrisome
  Dr J Swift, Dr Q-J Meng, Prof K E Kadler
Application Deadline: 31 January 2019
Circadian rhythm regulates and synchronises biological processes through a daily cycle. Molecular clocks in cells throughout the human body are entrained to a ‘master clock’ located in the hypothalamus, and cells in almost all tissues have been found to contain rhythmic genes.
  (BBSRC DTP) Mapping the structural and functional organisation of the human brain via in vivo neuroimaging and complex network analysis.
  Dr L Cloutman, Dr A Woollams
Application Deadline: 31 January 2019
The performance of the wide range of cognitive tasks we carry out in our daily lives including remembering, speaking, deciding and planning depends upon the interaction of complex networks of widely distributed brain regions.
  (BBSRC DTP) Are the pathways that protect tissues from mechanical stress lost in ageing?
  Dr J Swift, Dr S Richardson, Prof S Cartmell
Application Deadline: 31 January 2019
The defining qualities of our cells - their physical features and function - can be determined by their surroundings, but the tissue environment can be demanding.
  (BBSRC DTP) Cardiac Physiology in the World’s Oldest Vertebrate, The Greenland Shark
  Dr H Shiels, Dr G Galli, Dr A Stevens, Dr C Pinali
Application Deadline: 31 January 2019
The life span of the Greenland shark is at least 272 years and may be as long as 500 years making this animal the longest living vertebrate on the planet1.
  (BBSRC DTP) Elucidating the responses to nascent protein misfolding and aggregation stress
  Prof C M Grant, Prof S Hubbard, Prof M Ashe
Application Deadline: 31 January 2019
The aim of this study is to characterize the proteins that aggregate during nascent protein misfolding and to investigate how cells mitigate the damaging effects of aggregate formation.
  (BBSRC DTP) Factors educating myeloid cell progenitors in the bone marrow of wild mice
  Prof K Else, Dr J Grainger, Dr I Mair
Application Deadline: 31 January 2019
A multitude of factors such as infection history (Askenase et al. 2015), microbiota composition (Khosravi et al. 2014, Balmer et al.
  (BBSRC DTP) Integrating mechanical and biochemical signals in cell migration through membrane dynamics
  Dr P Caswell, Dr J-M Schwartz, Dr C Francavilla
Application Deadline: 31 January 2019
Cells respond to a myriad of cues from their environment, including mechanical signals from the extracellular matrix and biochemical cues from growth factors and cytokines.
  (BBSRC DTP) Integrative statistical inference methods for eukaryotic gene regulation with applications to embryonic stem cell differentiation
  Prof M Rattray, Dr I Iqbal, Prof A Sharrocks
Application Deadline: 31 January 2019
Embryonic stem cells (ESCs) can differentiate into different cell types through intermediary cell states and deeper understanding of the regulatory control underlying these differentiation stages is a very important topic in the study of mammalian development (Yang et al., 2014).
  (BBSRC DTP) Listeria monocytogenes in transit in the small intestine-interactions with the host mucosal surface and the host microbiota.
  Prof I Roberts, Prof D Thornton, Dr P Paszek
Application Deadline: 31 January 2019
Listeria monocytogenes is an opportunistic food borne pathogen responsible for a number of life threatening infections with a highest morality rate of any food borne bacterial pathogen.
  (BBSRC DTP) Microbial population diversity as a driver of antibiotic resistance evolution
  Dr D Gifford, Dr C Knight, Dr T Gilman
Application Deadline: 31 January 2019
Classically, microbial evolution has been thought to progress via rapid sweeps of beneficial mutations that quickly fix within populations—the so-called ‘strong selection, weak mutation’ model.
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