Biological Sciences (cells) PhD Projects, Programmes & Scholarships

We have 502 Biological Sciences (cells) PhD Projects, Programmes & Scholarships

The role of extracellular vesicles in lung epithelial cell communication in health and disease

University of Salford School of Science, Engineering and Environment

There is an opportunity to apply for a widening participation scholarship (available to UK candidates or those eligible for UK fees) can be found here. Read more

Supervisor: Dr P Miklavc

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the communication between cancer cells and cells in the tumour microenvironment to improve our understanding of epigenetic regulatory mechanisms and identify new targets for cancer therapy

University of Nottingham School of Medicine

It is well-established that the molecular mechanisms controlling gene expression are disrupted in cancer cells and work in this area has laid the foundations for targeted cancer therapies. We are interested in the regulatory pathways that control cell proliferation and cell migration and the events that disrupt this control in multiple types of cancer. Read more

Supervisors: Prof K Gaston, Dr S Jayaraman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Role of mechanical signals in a 3D human model of alveolar differentiation

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Alveolar epithelial type I (AT1) and type II (AT2) cells are essential for normal lung function following birth. Abnormal differentiation of AT1 and AT2 cells during development results in pulmonary pathology with associated neonatal mortality and long-term morbidity. Read more

Supervisors: Dr S Loukogeorgakis, Dr F Michielin, Prof P De Coppi

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Developing an ADAR-mediated RNA editing therapy for treatment of Duchenne Muscular Dystrophy

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Duchenne muscular dystrophy (DMD) is a severe X-linked genetic disorder affecting 1:5000 boys at birth (1). DMD is caused by mutations in Dystrophin gene, with around 10% of the cases caused by nonsense mutations (2,3). Read more

Supervisors: Dr HZ Zhou, Dr J Meng, Prof F Muntoni

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Determining metabolic reprogramming events in stem cells in response to inflammatory disease phenotype

University of Liverpool Institute of Life Course and Medical Sciences

Mesenchymal stem cells (MSCs) are responsible for the repair of damaged tissue following injury and disease as well as moderating innate and adaptive immune responses and regulation of self-tolerance and tissue homeostasis. Read more

Supervisors: Dr R Oldershaw, Dr A Chadwick, Dr M Phelan, Dr BN Norman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Optogenetic sculpting of next-generation organoids for disease modelling of congenital malformations including spina bifida

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

The ability to generate human induced pluripotent stem cells (iPSC) from adult cell types has revolutionised regenerative medicine research. Read more

Supervisors: Dr G Galea, Prof J Sowden

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Eliminating Harmful Cells to Maintain Homeostatis and Prevent Tumorigenesis

Cardiff University Cardiff School of Biosciences

Hamaratoglu Lab studies cell-cell signalling in development, homeostasis and tumourigenesis. We take advantage of outstanding genetic tools in Drosophila, and use larval imaginal discs as model epithelial organs. Read more

Supervisors: Dr F Hamaratoglu, Dr C Hogan

8 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Molecular mechanism of vimentin induced epithelial mesenchymal transition (EMT) and stemness in cancer cells

Queen Mary University of London Institute of Dentistry

Background. Most cancers are epithelial in origin and arise from a single progenitor cell, similar to an embryo, to become a clone of cells. Read more

Supervisors: Prof A Waseem, Dr H Tummala, Dr F Flores-Borja

Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic mechanisms causing malignant transformation of B cells and plasma cells

University of Leeds Faculty of Medicine and Health

Cancers of B cells and plasma cells, lymphomas and multiple myeloma, can be very aggressive, and often the cancer rapidly reoccurs after standard therapy. Read more

Supervisor: Prof U Klein

Year round applications PhD Research Project Self-Funded PhD Students Only

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Human Genetics, Genomics and Disease: Preventing and detecting chromosomal aneuploidy in human pluripotent cells

University of Edinburgh College of Medicine and Veterinary Medicine

Research Group: MRC Human Genetics Unit

Location. MRC Human Genetics Unit, University of Edinburgh, UK & Max Delbrück Center, Berlin, Germany. Supervisors. Prof Ian Adams, Prof Zsuzsanna Izsvák. Read more

Supervisor: Prof IA Adams

19 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Unlocking immune cells with tick-borne pathogens

University of Bristol Faculty of Health Sciences

In this project we will use tick-borne pathogenic bacteria as a molecular tool-kit for unlocking immune cells. These discoveries will help us combat tick-borne disease and provide a basis for manipulating immune cells, impacting on a wide range of diseases. Read more

Supervisors: Dr I Cadby, Dr J Mann, Dr E Ballou

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Relationship between IFNγ-dependent tumour escape and immunotherapy

University of Oxford Kennedy Institute of Rheumatology

Tumours actively escape the immune system by inducing an immunosuppressive state whereby intra-tumoural CD8 T-cells are “exhausted”, lacking effector functions. Read more

Supervisors: Dr A Gérard, Dr C Leung

3 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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The selective action of RAR ligands

University of Birmingham Institute of Cancer and Genomic Sciences

The cells that sustain a cancer and that are largely responsible for metastatic and aggressive disease are termed cancer stem cells. Read more

Supervisors: Dr M Hoogenkamp, Prof G Brown

30 April 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Investigating how dormant senescent cells can drive drug-resistance following chemotherapy

University of Dundee School of Medicine

Most anti-cancer chemotherapeutics work by inducing DNA damage and arresting the cell cycle in either G1 or G2 phase. A frequent outcome of this arrest is that cells exit the cell cycle into a state known as senescence. Read more

Supervisors: Dr A Saurin, Dr T Ly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Exploring the role of interferon stimulated genes (ISGs) in stem cells of serous ovarian cancer

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Epithelial ovarian cancer (EOC) is the leading cause of mortality in women due to gynaecological cancers. High-grade serous ovarian cancer (HGSOC) accounts for 70-80% of patients with EOC. Read more

Supervisors: Dr S Swaroop, Dr G Grimaldi, Dr ED Perkins

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 502 Biological Sciences (cells) PhD Projects, Programmes & Scholarships

Biological Sciences (cells) PhD Projects, Programmes & Scholarships

We have 502 Biological Sciences (cells) PhD Projects, Programmes & Scholarships

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