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We have 52 Biological Sciences (diabetes) PhD Projects, Programmes & Scholarships

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Biological Sciences (diabetes) PhD Projects, Programmes & Scholarships

We have 52 Biological Sciences (diabetes) PhD Projects, Programmes & Scholarships

Using single cell transcriptomic and blood proteomic data to understand how pancreatic cancer causes diabetes and to find ways to detect the cancer earlier

Pancreatic cancer is the deadliest of the common cancers. Five-year survival remains low at 12%. Sadly for 80% of patients, by the time their cancer is diagnosed it has spread to distant organs making them ineligible for potentially curative surgery. Read more

The INDICO-II Study – Effects of Body Composition and Dietary Improvement on Cell Membrane Dynamics and their Relationship with the Aetiology of Type II Diabetes

The InDiCo Study (Inflammation, Diets, body Composition) is a pre-clinical study conducted at the University of Worcester. The InDiCo Study is currently unravelling links between diets that favour a pro-inflammatory environment with biomarkers of cell function and body composition. Read more

NIHR Leeds BRC: Force sensing mechanisms of haemostasis in heart failure and diabetes

Since the original identification of the role of PIEZO1 in vascular integrity and endothelial cell biology by our group in Leeds in 2014, there have been many publications on the role of PIEZO1 in endothelial function and its role in processes such as atherosclerosis, hypertension, cell-cell junctions, vascular permeability and leukocyte diapedesis. Read more

NIHR Leeds BRC: Utilising genetic and genomic predictors of vasculitis and disease/treatment complications for application in routine clinical practice

There is substantial interest in using genetic biomarkers to predict those most at risk of disease and treatment complications; this is one of the focuses of Our Future Health, a national study aiming to recruit 5M participants ( https://ourfuturehealth.org.uk/ ). Read more

Interdisciplinary investigation of a large effect of sulfasalazine on HbA1c

The anti-inflammatory drug sulfasalazine, which is used in rheumatoid arthritis and inflammatory bowel disease, was reported earlier to suppress HbA1c in a small cohort of patients [1]. Read more

Neuronal control of appetite: investigating the role of the extracellular matrix in controlling neuronal activity in the hypothalamus

  Research Group: Chemistry and Biosciences
Appetite regulation is complex, and its dysregulation has serious implications for health, being observed in multiple conditions e.g., obesity, anorexia, and type 2 diabetes. Read more

Biological rhythms and the dopamine system in cognitive dysfunction

  Research Group: Pharmacology and Experimental Therapeutics
Psychiatric disorders such as schizophrenia are associated with metabolic syndrome, obesity and diabetes. Schizophrenia affects 1.1% of the population and although not the most common psychiatric condition it is arguably the most severe and debilitating. Read more

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