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We have 146 Biological Sciences (drugs) PhD Projects, Programmes & Scholarships

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Biological Sciences (drugs) PhD Projects, Programmes & Scholarships

We have 146 Biological Sciences (drugs) PhD Projects, Programmes & Scholarships

Psychedelic drugs and serotonergic modulation of functional connectivity in neuronal microcircuits

Psychoactive drugs result in profound alterations of our state of consciousness. Well known examples of such drugs are general anaesthetics, in use since mid-19th century, and psychedelics, which are consumed by different societies from times immemorial. Read more

Enzyme-responsive peptide hydrogels as in situ forming long-acting drug delivery implants

One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more

Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more

New Drugs for Brain Tumours: A Locoregional Implant Brain Tumours

  Research Group: Medicines Development and Pharmaceutical Sciences
Next-generation temozolomide derivatives for the treatment of high-grade glioma have been developed at the University of Bradford. Read more

Cancer: Repurposing drugs as new treatments for breast cancer

Breast cancer (BC) is the most common cancer, with over 1 million new cases diagnosed worldwide each year. For some types of BC, hormonal treatments have been very effective but one particular BC subtype, triple negative breast cancer (TNBC), is highly aggressive and lacks a targeted therapy. Read more
Last chance to apply

Pharmacological effect of psychedelics drugs in chronic pain

Psychedelic drugs, such as dimethyl tryptamine (DMT), lysergic acid diethylamide (LSD) and psilocybin (originally derived from mushrooms) cause a profound alteration of perception and mood and are being investigated clinically to treat a range of neuropsychiatric disorders. Read more

New Drugs for Brain Tumours: Prodrugs of Diazopropyne

  Research Group: Medicines Development and Pharmaceutical Sciences
The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more

Pharmaceutical process development, optimization and scale-up of plant-based cancer drugs

Project - We are pleased to announce an exciting PhD opportunity within our ground-breaking project dedicated to the optimization of extraction and purification processes of plant-derived molecules, with potential applications in cancer treatment as a collaborative effort with the South Australian immunoGENomics Cancer Institute. Read more

Wearable Healthcare Sensor for Continuous Monitoring of Critical Biomarkers and Therapeutic Drugs

Supervisory Team.   Prof. Xize Niu, Prof. Pete Worsley, Prof. Michael Ardern-Jones. Project description. Wearable sensors measure various physical, chemical, and biological information in real-time and continuously and in a non-invasive or minimally invasive manner. Read more

Towards the development of a novel class of broad-spectrum anti-infective drugs

Through exceptionally strong research collaborations at the interface of chemistry, biology, and medicine, we have applied innovative thinking to the field of (Minor Groove Binders) MGBs to develop a novel platform for drug discovery with the potential to treat an impressive range of diseases, including bacterial, fungal, parasitic, and viral infections. Read more

Natural toxins and their synthetic analogues as tools to study ion channels and as potential drugs and pesticides

The project will use a combination of electrophysiological techniques such as voltage-clamp and patch-clamp with molecular biology and protein expression to understand how natural toxins and their synthetic analogues act on ion channels in the nervous system. Read more
Last chance to apply

NUAcT PhD Studentship: Drug discovery in Motor Neuron Disease

Award summary. An annual stipend equivalent to UKRI doctoral stipend (23/24 rate at £18,622). Full fees at the UK home rate. International candidates will need to pay the difference between home and international fees. Read more

Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the role in acquired drug resistance in colon cancer

  Research Group: Institute of Cancer Therapeutics
Despite treatment advances, one of the most common cancers, colorectal cancer (CRC), still has a 45% mortality rate, and one of the major problems is the build-up of resistance to cancer drugs during treatment (‘acquired resistance’) such that over time the drugs stop working. Read more

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