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We have 13 Biological Sciences (genetic manipulation) PhD Projects, Programmes & Scholarships

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Biological Sciences (genetic manipulation) PhD Projects, Programmes & Scholarships

We have 13 Biological Sciences (genetic manipulation) PhD Projects, Programmes & Scholarships

Genome mining of novel antimicrobial natural products

These projects are open to students worldwide, but have no funding attached. Therefore, the successful applicant will be expected to fund tuition fees at the relevant level (home or international) and any applicable additional research costs. Read more

Linking metabolism and metal resistance in pathogenic bacteria (SULLIVANM_U24AMSSCI)

Primary supervisor - Dr Matthew Sullivan. Group B Streptococcus (GBS) is an effective pathogen of humans and animals and is well known as the leading cause of often-fatal infections in newborn infants. Read more

Natural products in bacterial physiology and chemical interaction

Microbial natural products have diverse chemical structures and bioactivities, which range from cell-cell signalling, nutrient acquisition, antifungal and antibacterial activity to stress resistance (1). Read more

The impact of nutritional scavenging on host-pathogen interactions, antifungal efficacy and emergence of antifungal resistance

Infections caused by Aspergillus fumigatus (Af) cause more deaths globally than any other fungal disease. Over 20 million are affected annually with four million having life threatening invasive and chronic infections with high morbidity and mortality up to 90%. Read more

Cellular mechanisms of equal chromosome segregation and genome stability

The PhD project will investigate how chromosomes segregate equally in each cell division through epigenetic regulation of the centromere, and how cells respond in stress conditions to maintain genome instability. Read more

The circadian clock as a regulator of information processing

Endogenous biological clocks are a ubiquitous feature of living organisms, driving rhythms in countless cellular and physiological functions, and influencing almost all biological processes. Read more

Immunotherapy: Manipulating T cell metabolism to improve anti-tumour immunity

The induction of immune responses to tumours can provide long-lasting protection from cancer. In this regard, T cells can suppress tumour growth by directly killing cancer cells and by producing inflammatory cytokines. Read more
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