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Biological Sciences (innate) PhD Projects, Programmes & Scholarships

We have 30 Biological Sciences (innate) PhD Projects, Programmes & Scholarships

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Helminth products as macrophage “trainers”: a novel tool to induce anti-inflammatory trained immunity

Kingston University Faculty of Health, Science, Social Care and Education
The innate immune system can display characteristics of immunological memory. This phenomenon, termed “trained immunity”, refers to the long-term functional reprogramming of innate immune cells after the encounter with infectious or non-infectious agents that influences their capacity to respond to a secondary stimulus. Read more
 Supervisor: Dr N Garrido Mesa
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating sex differences in innate immune signalling pathways with relevance to disease

Maynooth University Institute for Human Health Research
We are seeking a PhD student to work in an immunology-focused project. The funded postgraduate student stipend is €18,500 per annum (tax exempt). Read more
 Supervisor: Dr M Butler
 3 June 2024  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Molecular mechanism of innate immunity mediated by the Toll/IL1 receptor signalling pathways

University of Cambridge Department of Biochemistry
Our research aims to elucidate the molecular and cellular regulation of innate immune signal transduction in the context of infectious, inflammatory and autoimmune disease. Read more
 Supervisor: Prof N J Gay
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

University of Birmingham School of Biosciences
Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more
 Supervisor: Dr M Soller
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Interaction between innate immune activation and endothelial cells, linked to adverse cardiovascular events

University of Liverpool Institute of Systems, Molecular and Integrative Biology
The complement system is a key component of the immune response. Maintaining a balance between activation and inhibition of the complement system is key to preserving tissue homeostasis and enabling immune surveillance. Read more
 Supervisors: Dr N Liptrott, Dr R Rainbow, Prof C Dart
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Using a zebrafish tumour initiation model, single cell transcriptomics and in vivo live imaging to dissect mechanisms driving the development of tumour promoting neutrophils from the inception of cancer.

University of Edinburgh College of Medicine and Veterinary Medicine
  Research Group: Edinburgh Cancer Research Centre
Students will be registered for their degree at either the University of Glasgow or Edinburgh, depending on the project they apply for. Read more
 Supervisors: Dr A Khamseh, Dr L Carlin, Dr X Fu, Dr Y Feng
 20 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Ejecting infection: Understanding how epithelial tissues rid themselves of viral infections by apical extrusion

University of York York Biomedical Research Institute
Background. The epithelial tissues of our bodies use physical barriers and innate defences to fight viral infection. Read more
 Supervisor: Dr S Baker
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the regulation of neutrophil gene expression by intracellular signalling and small non-coding RNAs

University of Liverpool Institute of Life Course and Medical Sciences
Immune-mediated inflammatory diseases (IMID) such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) affect millions of people worldwide and cause debilitating and disabling musculoskeletal disease. Read more
 Supervisors: Dr HL Wright, Prof MJ Peffers
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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PhD position in antiviral immunity and vaccinology (m/f/d)

University Hospital of Munich Clinical Pharmacology
The Hospital of the University of Munich, Germany, is one of the largest and most competitive university hospitals in Germany and Europe. Read more
 Supervisor: Prof S Rothenfusser
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Creating patient-specific retinal organoids from human induced pluripotent stem cells for in vitro simulation of uveitis

University of Bristol Bristol Medical School
Uveitis, although uncommon, is a notable cause of visual impairment and blindness. Uveitis encompasses a range of conditions driven by both innate autoinflammatory and adaptive autoimmune CD4 T-cell responses. Read more
 Supervisor: Dr P Maghsoudlou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Defining the mechanistic basis of Aspergillus fumigatus and Non-tuberculous mycobacteria coinfection

The University of Manchester Faculty of Biology, Medicine and Health
Respiratory infections caused by bacteria, fungi and viruses are a global cause of death according to the WHO. Respiratory coinfections are on the rise and in general linked with poor patient outcomes. Read more
 Supervisors: Dr S Gago, Dr CK Kosmidis, Prof L Tabernero
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Haematology: Oncogenic reprogramming of immune cells

University of Leeds Faculty of Medicine and Health
Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory. Read more
 Supervisors: Dr F Errington-Mais, Dr P Laslo
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Linking metabolism and metal resistance in pathogenic bacteria (SULLIVANM_U24AMSSCI)

University of East Anglia School of Biological Sciences
Primary supervisor - Dr Matthew Sullivan. Group B Streptococcus (GBS) is an effective pathogen of humans and animals and is well known as the leading cause of often-fatal infections in newborn infants. Read more
 Supervisor: Dr MS Sullivan
 31 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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(MRC DTP CASE) The emerging fungal order Mucorales: species-specific pathogenic strategies and new diagnostics

The University of Manchester Faculty of Biology, Medicine and Health
Mucormycoses are emerging lethal fungal infections, with striking mortality rates of 50-90% depending on the clinical presentation, infection site and underlying host immune status. Read more
 Supervisors: Dr M Bertuzzi, Dr N.V.R Van Rhijn
 13 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Self-funded PhD- Understanding the molecular mechanism of a bacterial genome defence system and its synergy with CRISPR-Cas

University of Bristol School of Biochemistry
Prokaryotes have evolved over billions of years alongside their viruses, the bacteriophages, or “phages”. To prevent viral infection, prokaryotes have evolved rudimentary immune mechanisms, the most widespread and well-studied of which are the Restriction-Modification and the CRISPR-Cas enzymes. Read more
 Supervisor: Prof M D Szczelkun
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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