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Biological & Medical Sciences PhD Projects, Programs & Scholarships

We have 3,845 Biological & Medical Sciences PhD Projects, Programs & Scholarships

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  Uncovering the role of ASPM in mitosis
  Research Group: BBSRC White Rose DTP
  Prof M Peckham, Dr J Bond
Application Deadline: 6 January 2020

Funding Type

PhD Type

ASPM (abnormal spindle-like, microcephaly-associated protein) is essential in determining the plane of division in mitosis. This is important in regulating neuronal development, and enabling humans to have a large brain.
  Uncovering the role of long non-coding RNAs in uterine function for food, fertility, and health
  Research Group: BBSRC White Rose DTP
  Dr N Forde, Dr J Aspden
Application Deadline: 6 January 2020

Funding Type

PhD Type

In all mammalian species studied the majority of pregnancy loss occurs prior to implantation of the embryo into the uterine endometrium.
  Understanding amyloid aggregation mechanisms of alpha- and gamma synuclein in vitro and in vivo
  Research Group: BBSRC White Rose DTP
  Dr P van Oosten-Hawle, Prof S E Radford
Application Deadline: 6 January 2020

Funding Type

PhD Type

A key pathological hallmark of synucleopathies, including Parkinson’s Disease (PD) and Amyotrophic Lateral Sclerosis (ALS), is the formation of cytotoxic alpha-synuclein and gamma-synuclein aggregates respectively, that lead to neuronal cell death.
  Understanding how intrinsic disorder drives the formation of fuzzy protein complexes and tunes protein function
  Research Group: BBSRC White Rose DTP
  Dr S Kepinski, Dr A Zhuravleva, Prof N A Ranson
Application Deadline: 6 January 2020

Funding Type

PhD Type

Intrinsically disordered protein regions lack stable structure and instead move stochastically through an ensemble of conformations.
  Understanding mechanisms of small-molecule inhibition of the mitochondrial chaperonin HSPD1
  Research Group: BBSRC White Rose DTP
  Dr R.S. Bon, Dr S Muench, Dr H Wurdak
Application Deadline: 6 January 2020

Funding Type

PhD Type

Glioblastoma multiforme (GBM) is the most aggressive form of brain cancer. Treatment options are insufficient, survival rates are low.
  Understanding molecular motors through imaging and modelling
  Research Group: BBSRC White Rose DTP
  Dr SA Harris, Prof M Peckham, Dr O.G. Harlen
Application Deadline: 6 January 2020

Funding Type

PhD Type

Dimeric coiled coils are formed by two alpha helices that wrap around each other to bury hydrophobic residues. They are found widely throughout the proteome, and have important mechanical roles in proteins.
  Understanding the negative sense RNA intermediate in picornavirus replication
  Research Group: BBSRC White Rose DTP
  Prof N J Stonehouse, Prof D.J. Rowlands
Application Deadline: 6 January 2020

Funding Type

PhD Type

Picornaviruses are responsible for a number of serious diseases, including polio and foot-and–mouth disease. There is an urgent need to develop new strategies to address the continuing issue of picornavirus infection.
  Understanding the role maternal environmental stressors play in endometrial cell signaling: consequences for food, fertility and health.
  Research Group: BBSRC White Rose DTP
  Prof J.E. Ladbury, Dr N Forde
Application Deadline: 6 January 2020

Funding Type

PhD Type

Correct and appropriate function of the uterine endometrium is essential for early pregnancy success in mammalian species and dysregulation of signaling in this tissue leads to pregnancy loss and disease progression.
  Unraveling mechanisms for phosphate acquisition from soil and waste water via structural characterization of cellular components
  Research Group: BBSRC White Rose DTP
  Dr Y Benitez-Alfonso, Prof A Baker, Dr R Frank
Application Deadline: 6 January 2020

Funding Type

PhD Type

Phosphorus is essential to all living organisms but limited in its biological active form while at the same time representing a major contaminant in waste water.
  Virus manipulation of host cell micro-RNAs to regulate gene expression
  Research Group: BBSRC White Rose DTP
  Dr A MacDonald, Prof A Whitehouse
Application Deadline: 6 January 2020

Funding Type

PhD Type

micro-RNAs (miRNAs) are abundant endogenous RNAs and emerging evidence suggests they regulate gene expression by multiple processes.
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