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University of Edinburgh Biological & Medical Sciences PhD Projects, Programs & Scholarships

We have 34 University of Edinburgh Biological & Medical Sciences PhD Projects, Programs & Scholarships

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  Building novel in vitro models to generate musculoskeletal interfaces using 3D bioprinting
  Dr J Paxton
Applications accepted all year round

Funding Type

PhD Type

Musculoskeletal interfaces are the areas of the body where tissue types meet, for example the bone-tendon, bone-cartilage and muscle-tendon junctions.
  Developing novel stem cell approaches towards next-generation regenerative therapies
  Dr X Donadeu
Application Deadline: 10 April 2020

Funding Type

PhD Type

We seek an enthusiastic PhD student with combined interests in stem cell biology and regenerative medicine to undertake an exciting project aimed at taking recent advances in the field of stem cells to the development of novel and effective tissue regeneration approaches.
  Doctoral Programme in Precision Medicine – 4 year fully funded PhD

Funding Type

PhD Type

We are offering up to 32 PhD studentships in 2020/21 to high quality UK/EU applicants, providing full tuition fee and a stipend of at least £15,285 per year.
  Enabling large trials for the prevention of dementia
  Research Group: Centre for Clinical Brain Sciences
  Dr W Whiteley, Dr G Muniz-Terrera
Application Deadline: 3 April 2020

Funding Type

PhD Type

The post-holder will be responsible for the preparation and analysis of large datasets held in Canada and Scotland in order to plan for the delivery of clinical trials, and epidemiological contributors to dementia risk.
  Investigating human stem cell-derived cortical neurons with the G51D a-synuclein mutation as a model for dementia with Lewy bodies
  Research Group: MRC Centre for Regenerative Medicine
  Dr T Kunath, Dr M Zagnoni
Application Deadline: 3 April 2020

Funding Type

PhD Type

Dementia with Lewy bodies (DLB) is the second most common type of dementia after Alzheimer’s. It is characterised by a-synuclein-positive inclusions in the cortex called Lewy bodies.
  Investigation of mechanisms of neuroprotective oxidative stress response induction by mesenchymal stem cell extracellular vesicles using human pluripotent stem cell resources
  Research Group: Centre for Clinical Brain Sciences
  Dr P De Sousa, Dr T Wishart
Application Deadline: 3 April 2020

Funding Type

PhD Type

Adult-tissue derived mesenchymal stem cells (MSC) and derivative extracellular vesicles (EV) attenuate neuroinflammation, and elicit neuroprotective oxidative stress response in animal and cell models of neurodegenerative diseases and injury.
  Precision Medicine DTP - A personalised automatic approach for assessing and modelling the brain deep tissue waste drainage related structures
  Research Group: Centre for Clinical Brain Sciences
  Dr M Valdes Hernandez, Prof J Wardlaw, Dr M Bernabeu
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Previous experiments (Kress 2014) have suggested that brain features known as perivascular spaces play an important role in the clearance of metabolic waste from the brain tissue.
  Precision Medicine DTP - An integrated computational-experimental approach to identify and optimise combination drug therapy for non-alcoholic fatty liver disease (NAFLD)
  Research Group: Centre for Inflammation Research
  Prof J Fallowfield, Dr F Menolascina, Prof J Plevris
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Non-alcoholic fatty liver disease (NAFLD) is the commonest cause of chronic liver disease (CLD), affecting 1 in 4 people worldwide.
  Precision Medicine DTP - Analysing and recommending personalised care pathways for multimorbid patients with the use of artificial intelligence techniques
  Research Group: Centre for Medical Informatics
  Dr A Manataki, Dr D Wake, Dr S Cunningham
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Multimorbidity is one of the biggest challenges that health services are facing in the UK and worldwide. Care for people living with multiple conditions accounts for over half of the costs of primary and secondary care in the UK, and the number of these patients is rising.
  Precision Medicine DTP - Comprehensive study of miRNAs biogenesis in human cancer
  Dr G Michlewski, Dr C Kutter
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. MicroRNAs (miRNAs) are short non-coding RNAs ~22 nt in length that function as important regulators of gene expression1.
  Precision Medicine DTP - Data-Driven Decision Making for Paediatric Triage in Acute Care
  Dr A Shah, Prof S Cunningham
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Respiratory diseases affect hundreds of millions of people in both the economically developing and developed world causing morbidity and mortality [1].
  Precision Medicine DTP - Defining and predicting the molecular basis for male infertility
  Research Group: MRC Human Genetics Unit
  Dr J Marsh, Dr J Welburn
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Male infertility is on the rise. While the genetics and molecular mechanisms underlying the phenomenon remain poorly understood, mutations in >75 human protein-coding genes have already been confidently linked to male infertility (Oud et al, 2019).
  Precision Medicine DTP - Developing data science approaches to improve paediatric critical care patient flows and its related health economics benefits in Scotland
  Research Group: Centre for Medical Informatics
  Dr T Lo, Dr A Manataki, Dr L Moss, Dr A Neilson
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Paediatric critical care (PCC) is a highly valued specialist service that saves infants and children’s life. Over the past decade, the demand of PCC beds exceeds the expected population growth in the UK.
  Precision Medicine DTP – Development of clinically relevant models of undifferentiated pleomorphic sarcoma using a genetic screening approach
  Research Group: Edinburgh Cancer Research Centre
  Prof V Brunton, Dr L Boulter, Dr M Taylor, Prof D M Salter
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Sarcomas are relatively uncommon cancers thought to arise from pluripotent mesenchymal stem cells. Undifferentiated pleomorphic soft tissue sarcoma (UPS), though one of the commonest sarcoma subtypes encountered, exemplify the limitations of historical progress in sarcoma therapy.
  Precision Medicine DTP - Dissecting the biophysics of ocular transcription factors in vivo
  Research Group: MRC Human Genetics Unit
  Dr D Papadopoulos, Prof W Bickmore, Prof V Vukojevic
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Of the ~1,600 human TF genes, up to ~25% (~400 genes) are expected to be haploinsufficient with a plethora of them leading to developmental disorders1, underlining that transcription factor (TF) abundance (dosage) plays a major role during cell and tissue specification.
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