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University of Bradford Biological & Medical Sciences PhD Projects, Programs & Scholarships

We have 52 University of Bradford Biological & Medical Sciences PhD Projects, Programs & Scholarships

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Biological & Medical Sciences

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University of Bradford

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We have 52 University of Bradford Biological & Medical Sciences PhD Projects, Programs & Scholarships

How effective is 3D reconstructed human skin as an alternative to human skin for permeation studies?

  Research Group: Medicines Development and Pharmaceutical Sciences
The assessment of percutaneous absorption of molecules is a very important step in the evaluation of any transdermal drug delivery system. Read more

Targeting the MAPK scaffold protein KSR1 for the treatment of prostate cancer

  Research Group: Institute of Cancer Therapeutics
Prostate cancer is one of the leading causes of male cancer deaths. It arises when individual cells escape their normal growth control mechanisms and proliferate in an uncontrolled fashion. Read more

Investigation of antagonism of multiple RGD-binding integrins as a therapeutic strategy in advanced head and neck cancer

  Research Group: Institute of Cancer Therapeutics
Background. The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more

Phenotypic characterisation of red and white blood cells from patients with Type 2 diabetes mellitus

  Research Group: Chemistry and Biosciences
The prevalence of Type 2 diabetes (T2DM) is escalating at an alarming rate, with almost 10% of the UK population suffering from T2DM or in a pre-diabetic state. Read more

Central role of the adipokine chemerin in energy balance regulation and neuroinflammation

  Research Group: Chemistry and Biosciences
Multiple factors related to modern lifestyle, such as sedentary behaviour and overconsumption calorie-dense foods disrupt energy homeostasis and facilitate weight gain. Read more

Understanding skin ageing using a vascularised human skin equivalent model

The main purpose of this project is to develop a skin equivalent model that incorporates microvasculature, which will then be used to address several important questions in the area of skin ageing. Read more

Children and adolescents’ experiences of hearing voices when reading

  Research Group: Psychology
Many people have very vivid experiences of ‘hearing’ characters’ voices when they are reading novels or other texts and this seems to lead them to have more intense reading experiences (Alderson-Day, Bernini, & Fernyhough, 2017). Read more

Pharmaceutical cocrystallisation for improved medicines

  Research Group: Centre for Pharmaceutical Engineering Science
Active pharmaceutical ingredients (APIs) are frequently delivered to the patients in the solid-state formulation. Numerous tons of tablets are produced daily worldwide by pharmaceutical industry. Read more

The Impact of Befriending on Younger and Older Adults: An Intergenerational Project

  Research Group: Psychology
Intergenerational projects, bringing together younger and older adults, are increasingly common. Despite that, there is little research on friendship between different generations (O'Dare, Timonen, & Conlon, 2019). Read more

Aldehyde dehydrogenase expression and function in cancer stem cells

  Research Group: Institute of Cancer Therapeutics
Aldehyde dehydrogenases (ALDHs) catalyse the oxidation and detoxification of reactive endogenous and exogenous aldehydes into carboxylic acids via NAD+ coupled reduction. Read more

Biological rhythms and the dopamine system in cognitive dysfunction

  Research Group: Pharmacology and Experimental Therapeutics
Psychiatric disorders such as schizophrenia are associated with metabolic syndrome, obesity and diabetes. Schizophrenia affects 1.1% of the population and although not the most common psychiatric condition it is arguably the most severe and debilitating. Read more

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