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University of Hull Biological & Medical Sciences PhD Projects, Programs & Scholarships

We have 9 University of Hull Biological & Medical Sciences PhD Projects, Programs & Scholarships

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Biological & Medical Sciences

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Institution

University of Hull

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We have 9 University of Hull Biological & Medical Sciences PhD Projects, Programs & Scholarships

Re-purposing diabetes medicines to manage bleeding complications in myeloproliferative neoplasms.

Myeloproliferative neoplasms (MPNs) are a group of three related blood cancers in which the bone marrow overproduces one of the three cellular components of blood (erythrocytes, leukocytes and platelets). Read more

Modulation of platelet-mediated innate immune responses in chronic lymphocytic leukaemia

Chronic lymphocytic leukaemia (CLL) is the most common form of leukaemia in the Western World. B-cell receptor-induced intracellular signals are critical for the survival of leukaemia cells and disruption of this pathway by the Bruton’s tyrosine kinase (Btk) inhibitor ibrutinib is a highly effective CLL therapy. Read more

Identification of novel glucose-dependent alterations responsible for platelet dysfunction in Type 2 diabetes.

Type 2 diabetes mellitus (T2DM) is a growing global healthcare problem. Clinical findings suggest that more than 70% of patients with T2DM will die of cardiovascular diseases (CVDs) including heart attack and stroke. Read more

How does the vascular matrix environment influence platelet activation?

The platelet is a blood cell that plays a key role in the prevention of bleeding. For platelets to form a clot or thrombus effectively, they must rearrange their actin cytoskeleton to withstand high shear stress from blood flow in the arteries. Read more
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