The University of Manchester Biological Sciences PhD Projects, Programmes & Scholarships

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(University of Manchester - University of Tokyo Dual Award) Computational evolutionary biomechanics of bipedal/quadrupedal locomotion in early hominids

The University of Manchester Department of Earth and Environmental Sciences

The transition to habitual upright walking is one of the defining features of the human (as opposed to the chimpanzee) lineage and understanding its evolution is therefore of extreme interest to palaeoanthropologists. Read more

Supervisors: Prof W Sellers, Prof N Ogihara

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

The University of Manchester Department of Chemistry

Ecteinascidin 743 (ET-743, Trabectedin) is a marine-derived natural organic compound approved for the treatment of soft tissue sarcomas. Read more

Supervisors: Prof E Takano, Prof H Oguri

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Data-driven optimal prediction of bacteria growth

The University of Manchester Department of Mechanical, Aerospace and Civil Engineering

This project is devoted to an AI-based prediction of bacteria growth and its control by antibiotics. In synthetic biology, an improved understanding of bacterial regulatory circuits is required to develop complex biological systems with functionalities beyond existing in nature [1, 2]. Read more

Supervisor: Dr S Utyuzhnikov

Year round applications PhD Research Project Self-Funded PhD Students Only

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Protein self assembly induced by multivalent biological metabolites

The University of Manchester Department of Chemical Engineering

In addition to being an energy source in biological reactions, recent discoveries suggest adenosine triphosphate (ATP) also plays a critical role in maintaining cell stability and preventing deleterious cellular processes through modulating biomacromolecular self assembly. Read more

Supervisor: Dr R Curtis

31 December 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Application of machine learning algorithms to medical images and clinical/DNA data

The University of Manchester Department of Electronic and Electrical Engineering

This project will develop an automated classifier or the estimation of prognosis of the illness using medical images of the human body, clinical data, and gene information. Read more

Supervisor: Dr F Costen

Year round applications PhD Research Project Self-Funded PhD Students Only

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New Methods for modelling cofactor-dependent enzyme structure and function

The University of Manchester Department of Chemistry

Enzymes are Nature’s catalysts and many used cofactors and/or coenzymes to catalyse their reactions. While AI and homology methods now often allow the useful prediction of protein structure from amino acid sequence, this can be more challenging when the protein/enzyme contain cofactors. Read more

Supervisor: Prof S Hay

27 October 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Data-driven optimal prediction of bacteria growth

The University of Manchester Department of Mechanical, Aerospace and Civil Engineering

This project is devoted to an AI-based prediction of bacteria growth and its control by antibiotics. In synthetic biology, an improved understanding of bacterial regulatory circuits is required to develop complex biological systems with functionalities beyond existing in nature [1, 2]. Read more

Supervisor: Prof R Breitling

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Characterising human sebum using NMR approaches

The University of Manchester Department of Chemistry

We have recently shown that skin secretions in particular sebum, has a critical diagnostic role in other diseases unrelated directly to the skin. Read more

Supervisors: Dr D K Trivedi, Prof M Nilsson, Prof GA Morris

Year round applications PhD Research Project Self-Funded PhD Students Only

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Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics

The University of Manchester Department of Chemistry

Plastics are a broad range of solid polymeric materials that have found widespread application globally. However, there has been a steady accumulation of discarded plastics and there is now growing awareness that they present a significant hazard to the natural environment and human health. Read more

Supervisor: Dr L Wong

Year round applications PhD Research Project Self-Funded PhD Students Only

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The role of Human cytomegalovirus glycoprotein polymorphisms in disease pathogenesis

The University of Manchester Faculty of Biology, Medicine and Health

Human cytomegalovirus (HCMV) produces asymptomatic infection in most immunocompetent individuals but thereafter establishes life-long infection with periodic reactivation and asymptomatic shedding. Read more

Supervisors: Prof P Vallely, Prof P Klapper

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discerning the role of metabolic proteins in nucleus

The University of Manchester Faculty of Biology, Medicine and Health

Pancreatic Ductal Adenocarcinoma (PDAC), which develops from cells lining pancreas ducts, represents 95% of all pancreatic cancer cases. Read more

Supervisor: Dr A Latif

Year round applications PhD Research Project Self-Funded PhD Students Only

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Evaluating the risk of biguanides and statins on cancer incidence and mortality rates: a mixed methods study combining pharmacoepidemiological and experimental approaches

The University of Manchester Faculty of Biology, Medicine and Health

In the UK, every two minutes someone is diagnosed with cancer and every four minutes someone dies from it– leading to more than 360,000 new cases and 160,000 deaths annually1. Read more

Supervisor: Dr A Latif

Year round applications PhD Research Project Self-Funded PhD Students Only

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The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

The University of Manchester Faculty of Biology, Medicine and Health

A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more

Supervisors: Dr R Hager, Dr M Harte, Dr J Glazier

Year round applications PhD Research Project Self-Funded PhD Students Only

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Using microRNA inhibitors to boost GABAergic inhibition as a genetic therapy for epilepsy

The University of Manchester Faculty of Biology, Medicine and Health

Epilepsy is a chronic neurological disease characterised by recurrent spontaneous seizures and cognitive co-morbidities. Current small molecule approaches to treating epilepsy are ineffective in a significant portion of cases, and are associated with substantial adverse effects. Read more

Supervisors: Dr G. Morris, Dr R Wykes, Prof R Baines

Year round applications PhD Research Project Self-Funded PhD Students Only

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Defining the protective effects of a commensal bacterial strain in skin barrier function and protection from disease

The University of Manchester Faculty of Biology, Medicine and Health

Maintaining a healthy skin barrier is vital for our health. In response to skin wounding, we have a well-orchestrated immune response that heals the breach. Read more

Supervisors: Prof S Cruickshank, Prof A McBain, Dr R Unwin

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 120 The University of Manchester Biological Sciences PhD Projects, Programmes & Scholarships

The University of Manchester Biological Sciences PhD Projects, Programmes & Scholarships

We have 120 The University of Manchester Biological Sciences PhD Projects, Programmes & Scholarships

(University of Manchester - University of Tokyo Dual Award) Computational evolutionary biomechanics of bipedal/quadrupedal locomotion in early hominids

(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

Data-driven optimal prediction of bacteria growth

Protein self assembly induced by multivalent biological metabolites

Application of machine learning algorithms to medical images and clinical/DNA data

New Methods for modelling cofactor-dependent enzyme structure and function

Data-driven optimal prediction of bacteria growth

Characterising human sebum using NMR approaches

Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics

The role of Human cytomegalovirus glycoprotein polymorphisms in disease pathogenesis

Discerning the role of metabolic proteins in nucleus

Evaluating the risk of biguanides and statins on cancer incidence and mortality rates: a mixed methods study combining pharmacoepidemiological and experimental approaches

The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

Using microRNA inhibitors to boost GABAergic inhibition as a genetic therapy for epilepsy

Defining the protective effects of a commensal bacterial strain in skin barrier function and protection from disease

We have 120 The University of Manchester Biological Sciences PhD Projects, Programmes & Scholarships

The University of Manchester Biological Sciences PhD Projects, Programmes & Scholarships

We have 120 The University of Manchester Biological Sciences PhD Projects, Programmes & Scholarships

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