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We have 11 University of Otago Biological Sciences PhD Projects, Programmes & Scholarships

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Biological Sciences

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University of Otago

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University of Otago Biological Sciences PhD Projects, Programmes & Scholarships

We have 11 University of Otago Biological Sciences PhD Projects, Programmes & Scholarships

Cancer Epigenetics project

Broad Project Summary: Cancer is a leading cause of morbidity and mortality worldwide. Epigenetic changes are now recognised as a hallmark feature of cancer, but our understanding of factors that are responsible for tumour spread still remains limited. Read more

Charting new neuronal survival pathways in Parkinson’s disease

The Neurodegenerative and Lysosomal Disease Laboratory is interested in uncovering the unknown molecular and cellular mechanisms of neurodegenerative diseases, particularly in the development of Parkinson’s disease and Batten disease. Read more

Genetic causes of novel neurodevelopmental disorders

The Rare Disorder Genetics / Bicknell lab is interested in characterising novel genetic syndromes, with three core motivations. -the difference we can make to families with rare disorders, through providing them with more information. Read more

Novel disease genes in brain development and decline

The Rare Disorder Genetics / Bicknell lab is interested in characterising novel genetic syndromes, with three core motivations. -the difference we can make to families with rare disorders, through providing them with more information. Read more

Exploring a novel neurodevelopmental disease gene using a zebrafish model

The Rare Disorder Genetics / Bicknell lab is interested in characterising novel genetic syndromes, with three core motivations. -the difference we can make to families with rare disorders, through providing them with more information. Read more

Identify novel approaches to combat multi drug resistant pathogens

Our research is focused on recalcitrant ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, andEnterobacter species) pathogens; especially hard-to-treat clinical isolates involved in multidrug resistance, biofilm infections and persistence. Read more

Protecting Mum: how hormones act on neural circuitry to regulate postpartum mood and behaviour

Mammals give birth to dependent offspring and significant parental involvement is required to ensure offspring survive. During pregnancy and in the early postpartum period, hormones act on neural circuitry to bring about key changes in a mother's mood and behaviour. Read more

Role of RyR2 posttranslational modification in arrhythmias

Cardiac arrhythmias remain the leading cause of death in patients with heart disease. An important trigger for arrhythmias is the inappropriate opening of the cardiac ryanodine receptor (RyR2). Read more

Sex differences in epicardial fat modulation of cardiac function

This project will aim to determine whether structural and physiological properties of epicardial adipose tissue are responsible for the sex differences in human myocardial function and cardiac arrhythmogenicity. Read more

Oxytocin neuron activity in lactation

Pulsatile secretion of the hormone, oxytocin, is essential for milk delivery during suckling and its secretion from the posterior pituitary gland is triggered by coordinated bursts of action potentials across the population of oxytocin neurons. Read more

Understanding the underlying pathological mechanisms to find a cure for Batten disease

The Neurodegenerative and Lysosomal Disease Laboratory is interested in the molecular and cellular basis of neurodegenerative disease, particularly how lysosome dysfunction influences the development of Batten disease and Parkinson’s disease. Read more
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