Biological Sciences (metabolism) PhD Projects, Programmes & Scholarships

We have 107 Biological Sciences (metabolism) PhD Projects, Programmes & Scholarships

Evaluating Bacterial Acid Production and pH Dynamics in a Real-Time In-Vitro Polymicrobial Biofilm Model

University of Nottingham School of Life Sciences

Dental caries still remains a severe problem for both health and the economy. This oral disease is multifactorial and biofilm-dependent, caused by changes in the composition and metabolism of complex communities of oral biofilm. Read more

Supervisors: Dr K Hardie, Prof J Aylott

5 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Dynamic Imaging for Real-Time Visualization of Bacterial Species Co-Distribution and Biofilm Matrix Components

University of Nottingham School of Life Sciences

Dental caries is a severe problem for both health and the economy. This oral disease is multifactorial and biofilm-dependent, caused by changes in the composition and metabolism of complex bacterial communities in oral biofilms. Read more

Supervisors: Prof J Aylott, Dr K Hardie

5 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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(MRC DTP CASE) Prediction of substrate binding geometry and strength in promiscuous enzymes: computational chemistry applicable to the design of pharmaceuticals and agrochemicals

The University of Manchester Faculty of Biology, Medicine and Health

We are often taught about the power of enzymes to select particular substrates from the biological milieu and of their ability to perform highly selective reactions on those substrates. Read more

Supervisors: Dr A Leach, Dr S De Visser, Dr C Trujillo

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Understanding the roles of triacylglycerol in modulating mycobacterial growth and biophysical properties

University of Leicester Department of Respiratory Sciences

Mycobacteria contain more lipid than any other bacteria. In addition to a characteristically lipid-rich cell envelope, mycobacteria can accumulate triacylglycerol (TAG) as cytoplasmic lipid bodies (LBs). Read more

Supervisors: Dr N Garton , Dr G Mukamolova

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Fully funded PhD studentship: Transforming respiratory care at the bedside using machine learning assisted on-chip vibrational spectroscopy

University of Southampton Faculty of Engineering and Physical Sciences

Supervisory Team. Prof. Senthil Murugan Ganapathy. Project description. Acute respiratory distress syndrome (ARDS), a widespread respiratory condition affecting all ages, causes respiratory failure due to inflamed, fluid-filled lungs hindering gas exchange. Read more

Supervisor: Prof S Ganapathy

Year round applications PhD Research Project Competition Funded PhD Project (European/UK Students Only)

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Self-funded PhD– Role of T and NK-cell immunity during dengue virus infection and impact of immune modulation during therapy

University of Bristol School of Cellular and Molecular Medicine

A PhD position is available to study the role of human T and NK-cell immunity during infection with dengue virus (DENV), a flavivirus that is transmitted by infected Aedes mosquitoes. Read more

Supervisor: Dr L Rivino

Year round applications PhD Research Project Self-Funded PhD Students Only

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The Role of Nutrition and Exercise in Physical and Cognitive Function (such as sarcopenia and frailty), utilizing clinical, metabolomic, proteomic, and gut microbiota data

University of Liverpool Institute of Life Course and Medical Sciences

Physical frailty is a result of hallmarks of aging, where gut microbiome (GM) dysbiosis and dietary pattern play a significant role. Read more

Supervisor: Dr M Isanejad

Year round applications PhD Research Project Self-Funded PhD Students Only

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PhD studentship - Defining the mechanisms underpinning HIF-1 and HIF-2 dependent transcriptional specificity in hypoxia.

Newcastle University Biosciences Institute

Award summary. 100% of home tuition fees paid and annual living expenses of £18,622. Overview. The cellular response to low oxygen levels (hypoxia), is crucial for cell survival and identity. Read more

Supervisor: Dr B Ortmann

14 June 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

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MScR: Involvement of astrocytes in neurological manifestations of Long COVID syndrome

University of Bristol School of Physiology, Pharmacology & Neuroscience

A significant fraction of patients affected by Long COVID, long-term consequences following acute SARS-CoV-2 infection, suffer from mental fatigue and cognitive deficits (1-3). Read more

Supervisor: Prof A Teschemacher

Year round applications PhD Research Project Self-Funded PhD Students Only

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Unravelling the role of P4HB in skeletal development: towards treatment of heritable bone fragility

University of Sheffield School of Medicine and Population Health

Osteogenesis Imperfecta (OI) affects 1 in 15-20,000 live births and results in a childhood with frequent fractures, reduced mobility and joint problems. Read more

Supervisor: Dr M Balasubramanian

Year round applications PhD Research Project Self-Funded PhD Students Only

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Precision Therapy for NBAS-related disorder

University of Sheffield School of Medicine and Population Health

It is very well recognised that rare diseases offer the potential to uncover new information about mechanisms underlying a range of phenotypes. Read more

Supervisor: Dr M Balasubramanian

Year round applications PhD Research Project Self-Funded PhD Students Only

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Mining data from National genomics Research Library to enable new gene discovery

University of Sheffield School of Medicine and Population Health

Whole Genome Sequencing (WGS) is a new genomic testing technology and process which became available through the NHS in April 2022. Read more

Supervisor: Dr M Balasubramanian

Year round applications PhD Research Project Self-Funded PhD Students Only

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Geomicrobiological controls on radionuclide speciation and fate during the geodisposal of radioactive waste

The University of Manchester Department of Earth and Environmental Sciences

Context. The UK has been generating electricity from nuclear power for over sixty years. Consequently, the safe disposal of the UK’s existing ~750,000 m3 of radioactive waste is a clear priority. Read more

Supervisors: Prof J Lloyd, Prof S Shaw, Dr A Uknnl

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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In silico modelling of endocannabinoid evolution

University of Worcester Research School

In the brain, the endocannabinoid (eCB) system maintains adequate neurotransmission (Lu and Mackie 2016). Indeed, the eCB system provides a negative feedback mechanism, preventing over-activation of synaptic transmission. Read more

Supervisor: Dr M Di Micelli

Year round applications PhD Research Project Self-Funded PhD Students Only

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