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Biomedical Engineering (amyloid) PhD Projects, Programs & Scholarships

We have 5 Biomedical Engineering (amyloid) PhD Projects, Programs & Scholarships

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  Investigating phenotypic, proteomic and functional changes in microglia in a preclinical model for sporadic Alzheimer’s disease research (Manchester-Melbourne Dual Award)
  Dr M Harte, Dr A Tirella
Application Deadline: 31 January 2020

Funding Type

PhD Type

Current treatments for Alzheimer’s disease (AD) are symptomatic and do little to slow down the progression of the disease. This has led to an array of research investigating hallmark pathologies in the search for novel therapeutic strategies.
  Are Tau fibrils induced by phosphorylation and the interaction with 14-3-3 proteins relevant for Alzheimer disease?
  Dr J Hritz, Dr JN Nováček, Dr J Pribyl
Application Deadline: 20 February 2020

Funding Type

PhD Type

Several neurodegenerative diseases are associated with the formation of fibrous protein aggregates. The fibrillization of amyloid beta peptide into amyloid plaques and the agregation of hyperphosphorylated tau protein into neurofibrillar tangles are main neuropatological signs of Alzheimer disease.
  Role of phosphorylated 14-3-3 proteins
  Dr J Hritz, Assoc Prof V Bryja
Application Deadline: 1 February 2020

Funding Type

PhD Type

14-3-3 proteins play key role in the neurobiochemistry of brain and are also associated with neurodegenerative amyloid diseases such as Alzheimer and Parkinson disease.
  A novel human 3D in vitro dynamic model with integrated sensors for studying neurovasculature inflammation
  Dr V Pensabene, Dr S Saha
Application Deadline: 30 April 2020

Funding Type

PhD Type

The brain microvasculature is composed of endothelial cells, pericytes and astrocytes. The endothelium forms the barrier between the blood and the brain cells (i.e “blood-brain barrier “, BBB).
  Bioactive Peptide Nanostructures: The relation between bioactivity and molecular self-assembly into diverse nanostructures
  Prof I W Hamley
Applications accepted all year round

Funding Type

PhD Type

Research into bioactive peptides includes work on antimicrobial peptides, amyloid-related peptides with relevance to protein misfolding diseases such as Alzheimers, lipopeptides with applications in immune therapies and for wound healing and skincare.
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