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Biophysics (antimicrobial) PhD Projects, Programs & Scholarships

We have 8 Biophysics (antimicrobial) PhD Projects, Programs & Scholarships

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  Cationic antimicrobial peptides as anticancer agents
  Dr R Green, Prof R A Frazier
Applications accepted all year round

Funding Type

PhD Type

Cationic peptides are widespread in nature where they play a key role in host defense within plants and animals. The mechanism by which these peptides interact with cell membranes potentially leads to these being less prone to antimicrobial resistance than conventional antibiotics.
  The bacterial protein translocation machinery: a target for new strategies against antimicrobial resistance
  Prof I Collinson
Applications accepted all year round

Funding Type

PhD Type

Bacterial resistance to antibiotics is a major problem affecting millions of people across the world. This severely affects treatment of bacterial infections as strains are emerging that are totally resistant to all clinically used antibiotics.
  Combining Synthetic Biology and Modelling to Understand and Predict Evolution
  Dr M Lagator, Dr J-M Schwartz
Applications accepted all year round

Funding Type

PhD Type

Mutations, and their effects on organismal fitness, lie at the heart of understanding and predicting evolution. Because of its central role in determining evolutionary outcomes, much experimental and theoretical effort has been put into describing the fitness effects of mutations.
  Using synthetic biology to understand the evolution of antibiotic resistance
  Dr M Lagator, Dr C Knight
Applications accepted all year round

Funding Type

PhD Type

Imagine an architect, tasked with converting an old stadium into a building with a different function, without demolishing it.
  Adjuvant therapies for mupirocin-resistant bacteria
  Dr B Bonev, Dr A Cockayne
Applications accepted all year round

Funding Type

PhD Type

Multi-drug resistant Staphylococcus aureus has been able to adapt constantly to therapeutic use of antibiotics and remains an important source of clinical complications, morbidity and mortality.
  High-throughput discovery of novel antibiotics using synthetic microbiology
  Dr R Draheim
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is a frequent problem in the treatment of disease caused by several clinical bacterial pathogens. In the European Union, antibiotic-resistant infections kill nearly 25,000 patients and represent a total expenditure of £1.5 billion per year.
  Structure-function relationships governing polyphenol bioactivity with respect to plasma membranes
  Prof R A Frazier, Dr R Green
Applications accepted all year round

Funding Type

PhD Type

This project aims to investigate polyphenol binding to lipid membrane surfaces with a view to understanding how polyphenol structure and aggregation within the gastrointestinal tract (GIT) affects the bioavailability of these nutraceuticals.
  Simulation-led enzyme engineering and design of antibiotic drugs
  Dr M van der Kamp
Application Deadline: 25 November 2019

Funding Type

PhD Type

The use of enzymes as biocatalysts is attractive for industry, but natural enzymes often need modification to efficiently produce the desired products.
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