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We have 24 Biophysics (protein structure) PhD Projects, Programmes & Scholarships

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Biophysics (protein structure) PhD Projects, Programmes & Scholarships

We have 24 Biophysics (protein structure) PhD Projects, Programmes & Scholarships

Fully Funded 4-Year Cheney Scholarship PhD Programme in In Situ Structural Biology

 Exciting new developments in imaging and structural methods, known as “in situ structural biology”, can reveal the structure and behaviour of biological macromolecules inside healthy and diseased cells and tissues. Read more

Structure and function of enzyme complexes involved in post-transcriptional gene regulation

Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics. Read more

Structure-function relationships governing polyphenol bioactivity with respect to plasma membranes

This project aims to investigate polyphenol binding to lipid membrane surfaces with a view to understanding how polyphenol structure and aggregation within the gastrointestinal tract (GIT) affects the bioavailability of these nutraceuticals. Read more

Untangling how Shelterin safeguards telomere structure and stability - one molecule at a time

Background. Telomeres solve two problems with linear chromosomes. the end-replication problem, DNA loss from the end of chromosomes every replication cycle; and the end-protection problem, protection of the chromosome ends to prevent chromosome fusions. Read more

Protein engineering enzymes for Industry

Project Overview. We are interested in key features of the protein sequence - structure - function relationship, and how this information can be translated to health. Read more

Understanding interactions of proteins with polymer-coated nanoparticles

Introduction. Polymer-coated nanoparticles are promising drug delivery vehicles. Multiple functionalities can be embedded into the nanoparticle structure to enable uptake of the drug-like molecules, their targeted delivery and controlled release. Read more

Understanding the evolution of gene regulatory networks through biophysical modelling and machine learning

The ability to coordinate the expression of genes within a cell is at the heart of life. When and how much of a specific gene is turned into a protein is essential for organisms to respond to their environment and to manage resources. Read more

Fully funded PhD student position in structural biology of viruses

PhD position in the structural biology of viruses. The Department of Chemistry is opening a PhD position in Chemistry with a specialization in structural biology. Read more

Chemical energy conversion in biology studied using advanced spectroscopic and structural tools

Redox properties of metal-containing active sites are critically important to many biocatalytic processes. one third of all proteins contain a redox-active metal, and ca 22% of submissions to the Protein Data Bank contain a transition metal. Read more

Investigating the role of P2X7 receptor intracellular domains in cell signalling

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more

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