Imperial College London Featured PhD Programmes
Imperial College London Featured PhD Programmes
The Chinese University of Hong Kong Featured PhD Programmes

Biophysics (structural) PhD Projects, Programs & Scholarships

We have 46 Biophysics (structural) PhD Projects, Programs & Scholarships

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We have 46 Biophysics (structural) PhD Projects, Programs & Scholarships

Structural biology of the Ccr4-Not nuclease complex using electron paramagnetic resonance (EPR) spectroscopy and integrative modelling

The ultimate goal in molecular biology is to understand normal physiology and disease processes at atomic resolution. Methods such as x-ray crystallography and NMR spectroscopy have been phenomenally successful in the past decades and continue to be the workhorses of structural biology. Read more

Using cryoEM to understand pathogen antibiotic transport and resistance

Background. A number of dangerous pathogens are increasingly resistant to our front-line antibiotics, raising the prospect of a ‘post-antibiotic era’ where we can no longer treat infectious diseases. Read more

Ion channel clustering in neuronal membranes

The aim of the study is to investigate the organization of ion channels in the membranes of excitable cells by scaffold proteins, and to discover how the properties of the channels are modified by these interactions. Read more

Structural analysis of the inter-membrane bacterial secretosome

Protein secretion is essential for life. Bacteria secrete proteins for a wide range of membrane and extracellular activities, including envelope biogenesis, pathogenicity and degradation of antibiotics. Read more

Neuroinflammation in Alzheimer’s disease: what is the role of amyloid-beta fibril structure?

This project will explore the role of amyloid-beta fibril structure in triggering neuroinflammation in Alzheimer’s disease. Alzheimer’s disease is the most common form of dementia and affects millions worldwide. Read more

Unravelling the structure and conformational dynamics of membrane proteins using H/D-exchange mass spectrometry and cryo-EM

A dynamic studentship which includes experience working in both academic and pharmaceutical industry environments. the project is performed in partnership between laboratories at both King’s College London and UCB Pharma (Slough, 20 miles West of Central London). Read more

Protein engineering enzymes for Industry

 . We are interested in key features of the protein sequence - structure - function relationship, and how this information can be translated to health. Read more

Mechanics of soft solids and structures under large deformation

Background. Solid materials that can undergo large deformations are ubiquitous in nature and are widely used to manufacture engineering components, devices and structures. Read more

MSc by Research programme - Bringing proteins together with small molecules

Recent advances from the Ciulli Lab and others have contributed to the establishment of a game-changing new modality of chemical intervention into biological system – one that goes significantly beyond the state-of-the-art. Read more

Simulation-led investigation and engineering of enzymes involved in abyssomicin antibiotic biosynthesis

Enzymes are remarkable biocatalysts that allow rapid, selective and efficient catalysis under mild conditions. Biotechnology exploits the outstanding rate-enhancing properties of these natural biocatalysts to manufacture high added-value products. Read more

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