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Biophysics (animal genetics) PhD Projects, Programs & Scholarships

We have 15 Biophysics (animal genetics) PhD Projects, Programs & Scholarships

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  Evolution of Reproductive traits - to elucidate the genetic and developmental basis of reproductive failure
  Dr N Hemmings
Applications accepted all year round

Funding Type

PhD Type

Sexual selection is underpinned by variation in reproductive success. Our research group studies the mechanisms underpinning this variation, primarily using birds as a model.
  Etiology, assessment and treatment of scoliosis
  Prof K Cheung
Applications accepted all year round

Funding Type

PhD Type

Scoliosis is an abnormal curvature of the spine that can be present in 3-4% of the population. If left untreated, some can progress to lead to back pain, shortness of breath and severe deformities.
  Scoliosis research and outcomes
  Dr J Cheung
Applications accepted all year round

Funding Type

PhD Type

Adolescent idiopathic scoliosis is the commonest form of spinal deformity in the paediatric population. Without proper treatment, these curves may deteriorate and lead to cosmetic disfigurement, back pain, and cardiopulmonary compromise.
  Protein Misfolding and the Molecular Basis of Alzheimer’s Disease
  Dr J Viles
Applications accepted all year round

Funding Type

PhD Type

Background. World-wide one in three people over the age of 65 will die with Alzheimer’s Disease (AD). The disease is characterised by deposits of amyloid plaques and fibrils of amyloid-beta peptide (Ab) are their main constituent.
  Investigating the mechanobiological mechanisms of cancer
  Dr K Erdmann
Applications accepted all year round

Funding Type

PhD Type

Cancer is the second-leading cause for death globally and there is a high demand for novel approaches to understand and treat cancer.
  A mechanistic understanding of allosteric regulation of neuronal sodium-activated potassium channels
  Research Group: School of Biomedical Sciences
  Dr J D Lippiat, Dr S Muench, Dr A Kalli
Applications accepted all year round

Funding Type

PhD Type

The sodium-activated potassium channel KNa1.1 (KCNT1, Slack, Slo2.2) is found in neurons and couples sodium influx to excitability.
  Defining a novel assembly pathway in ssRNA viruses using X-ray footprinting.
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

Project co-supervised by Prof. Peter Stockley at Leeds and Prof. Reidun Twarock at University of York, as part of the White Rose network "Structural and Mechanistic Biology at the RNA/Ligand Interface".
  Enhancing stability of biocatalyst for fuel cells and bioelectrocatalysis
  Prof L J C Jeuken, Dr P Beales
Applications accepted all year round

Funding Type

PhD Type

Progress in biotechnology over the last two decades has greatly increased the use of biocatalyst in the industrial production of fine chemicals.
  Learning from plant cell walls as a path for innovations in food and material sciences
  Dr Y Benitez-Alfonso, Dr C Bosch
Applications accepted all year round

Funding Type

PhD Type

The research will dissect the structural factors controlling cell walls and cell communication for two main purposes. to improve the health value of food crops and to design strategies for the valorisation of wasted plant materials.
  Mathematical Virology: A New Mathematical Approach to Viral Evolution Grounded in Experiment
  Research Group: Astbury Centre for Structural Molecular Biology
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

Mathematical modelling of natural phenomena has the potential to be predictive but requires direct verification by experiment. Such models can then be very powerful indicators of our understanding and they permit in silico simulations of situations that are difficult to test experimentally.
  Nanoinjection: a single molecule technique to study amyloid toxicity in neurons
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E W Hewitt, Prof S E Radford, Dr P Actis
Applications accepted all year round

Funding Type

PhD Type

Interested in amyloid disorders such as Parkinson’s and Huntington’s. Want to work with cutting edge technology in a multidisciplinary team.
  Structural insights into ligand binding and channel gating in ATP-gated P2X7 receptor
  Research Group: School of Biomedical Sciences
  Dr L H Jiang, Dr S Muench
Applications accepted all year round

Funding Type

PhD Type

P2X7 receptor, belonging to the ATP-gated ion channel P2X receptor family, exhibits distinct functional and pharmacological properties that are crucial for its role in innate immunity and inflammatory diseases and cancers (Jiang et al., 2013; Caseley et al., 2014; Roger et al., 2014; Wei et al., 2018).
  Synthetic Virology: Development of gene delivery vectors/synthetic vaccines
  Research Group: Astbury Centre for Structural Molecular Biology
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

There is worldwide interest in exploiting our modern understanding of genomics to target gene expression therapeutically via a variety of mechanisms, such as transgene insertion and CRISPR-Cas gene editing.
  The biomechanical mechanism of sports-related concussion
  Dr G Tierney
Application Deadline: 24 April 2020

Funding Type

PhD Type

There is a growing body of evidence regarding the risk of several neurodegenerative diseases associated with sports-related concussion (SRC).
  TRPM2 channel mechanism of neuroinflammation and neurodegeneration in Alzheimer’s disease
  Research Group: School of Biomedical Sciences
  Dr L H Jiang, Dr I Wood
Applications accepted all year round

Funding Type

PhD Type

Alzheimer’s disease (AD) is the most common cause of dementia and also a major cause of morbidity and mortality. Currently, there is no effective therapeutics to treat or slow the disease progress.
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