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Biophysics (biomedical science) PhD Projects, Programs & Scholarships

We have 55 Biophysics (biomedical science) PhD Projects, Programs & Scholarships

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  Investigating the mechanobiological mechanisms of cancer
  Dr K Erdmann
Applications accepted all year round

Funding Type

PhD Type

Cancer is the second-leading cause for death globally and there is a high demand for novel approaches to understand and treat cancer.
  UKRI Centre for Doctoral Training in Biomedical Artificial Intelligence

Funding Type

PhD Type

Building on a tradition of world-leading research and innovation at the University of Edinburgh, our Centre will train a new generation of interdisciplinary scientists who will shape the development of AI within biomedical research over the next decades.
  Unraveling corneal fibrosis mechanisms via the study of vimentin expression in corneal cells on electrospun membranes
  Dr I Ortega, Dr A Gad
Applications accepted all year round

Funding Type

PhD Type

It is estimated that 135 million people have severely impaired vision because of a loss of corneal transparency. Corneal blindness is considered the 4th largest cause of blindness worldwide, after cataracts, glaucoma and macular degeneration.
  Platform Technology to Enhance the Growth of Human Tissues In Vitro for Use in Biomedical Research and the Assessment of New Molecular Entities
  Prof S A Przyborski, Prof T von Zglinicki
Application Deadline: 29 May 2020

Funding Type

PhD Type

Many molecules fail when tested in humans as activity data do not always extrapolate into man. Accordingly, there is demand to develop new biomedical in-vitro assays to test compounds in human tissues earlier in product development.
  Mechanics of Advanced Materials: the response of advanced engineering and bio-materials to various types of external loading and environmental conditions - Ref: VS2UF2018
  Prof V Silberschmidt
Application Deadline: 3 September 2020

Funding Type

PhD Type

In the last two decades, Mechanics of Materials as a discipline has experienced a type of revival. The main reason for this has been a continuing introduction of new materials (or even their classes) with extraordinary microstructures, properties and performance.
  High-throughput discovery of novel antibiotics using synthetic microbiology
  Dr R Draheim
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is a frequent problem in the treatment of disease caused by several clinical bacterial pathogens. In the European Union, antibiotic-resistant infections kill nearly 25,000 patients and represent a total expenditure of £1.5 billion per year.
  Stimuli-responsive biopolymers for life science, materials and therapeutic applications
  Dr M Soloviev
Applications accepted all year round

Funding Type

PhD Type

This is a self-funded project, match-finding option may be available for qualifying candidates. Please include a detailed CV with any enquiries.
  Computer models of structural and molecular changes during learning
  Dr M Stefan
Application Deadline: 4 June 2020

Funding Type

PhD Type

This project is one of 16 four year PhD Studentships funded by Medical Research Scotland (https://www.medicalresearchscotland.org.uk) to be delivered jointly by the named University and External Partner Organisation (EPO).
  Mechanics of biomaterials: characterisation and quantification of interaction between microstructure and mechanical properties - Ref: VS1UF2018
  Prof V Silberschmidt
Application Deadline: 3 September 2020

Funding Type

PhD Type

Understanding mechanical properties and performance of various biological materials and tissues and their responses to different loading and environmental conditions is becoming increasingly important for development of new medical procedures and devices.
  PhD position in Image Reconstruction for Next Generation X-Ray Tomography
  Prof S Arridge
Applications accepted all year round

Funding Type

PhD Type

A multidisciplinary consortium from UCL comprising the Advanced X-Ray Imaging group in the Department of Medical Physics and Biomedical Engineering, the…
  Evolution of Reproductive traits - to elucidate the genetic and developmental basis of reproductive failure
  Dr N Hemmings
Applications accepted all year round

Funding Type

PhD Type

Sexual selection is underpinned by variation in reproductive success. Our research group studies the mechanisms underpinning this variation, primarily using birds as a model.
  Characterising and repurposing cyanobacterial CO2-fixing organelles for metabolic engineering
  Prof LN Liu, Dr J Hartwell
Applications accepted all year round

Funding Type

PhD Type

Compartmentalisation represents an effective strategy used by cells to enhance their activities. By creating physical barriers and compartments, cells sequester the metabolic pathways from the cellular milieu to allow controls of metabolic flux and toxic diffusion.
  Elucidating Disease Mechanisms using New Approaches to Capture Transient Protein Complexes in the Mitochondria
  Prof L-Y Lian
Applications accepted all year round

Funding Type

PhD Type

The mitochondria is the powerhouse of the cell. Its malfunction is the cause of many diseases, ranging from cancer to heart and neurological diseases, which become more prevalent with age.
  Evolutionary insights for engineering improved globin oxygen carriers
  Dr M Berenbrink, Dr J Madine
Applications accepted all year round

Funding Type

PhD Type

Around 2 million red blood cell units at a cost of 120.00 GBP per unit are transfused annually in England alone (http://www.nhsbt.nhs.uk/what-we-do/blood-transfusion/).
  Exploiting advanced methods for protein structure prediction
  Prof D J Rigden, Dr R Keegan
Applications accepted all year round

Funding Type

PhD Type

Protein structural information is crucial for an understanding of protein function and evolution. Currently, there is only experimental data for a tiny fraction of the protein universe.
  Improving Photosynthetic Efficiency - Engineering and Evolution of Light-Harvesting Complexes via Synthetic Biology
  Dr D Canniffe
Applications accepted all year round

Funding Type

PhD Type

Photosynthesis is the ultimate source of food and energy for almost all forms of life. Using sunlight as the energy input, photosynthesis removes carbon dioxide from the atmosphere generating the oxygen and carbohydrate that support complex life.
  Investigating the molecular mechanisms and consequences of ANP aggregation for cardiovascular disease; a computational and experimental approach
  Dr J Madine, Prof D J Rigden, Dr M Winn
Applications accepted all year round

Funding Type

PhD Type

Atrial natriuretic peptide (ANP) is a cardiovascular hormone synthesised and secreted by myocytes in the atrial wall where it regulates atrial blood volume and vasodilation.
  Mass spectrometry analysis of human tissue to characterise cleavage events resulting in amyloid deposition associated with aortic aneurysm and dissection
  Dr J Madine, Prof C E Eyers
Applications accepted all year round

Funding Type

PhD Type

The most common form of localised amyloid occurs in the aorta (aortic medial amyloid; AMA) and is estimated to occur in 97% of Caucasian people over 50.
  Methionine adenosyltransferases in disease and regulation of gene expression
  Dr S Antonyuk, Prof S Hasnain
Applications accepted all year round

Funding Type

PhD Type

Transmethylation, the transfer of a methyl group from one molecule to another, is a fundamental chemical reaction that plays a central role in important biological processes such as gene expression, cell growth and apoptosis.
  Mitochondrial protein folding and diseases
  Prof L-Y Lian, Dr D Criddle
Applications accepted all year round

Funding Type

PhD Type

Many diseases, including cancer and neurological disease, stem from mitochondrial dysfunctions often triggered by sudden elevation of agents such as calcium and reactive oxygen species.
  SOD1 The Key protein for finding a cure for familial Motor Neurone Disease
  Dr S Antonyuk, Prof S Hasnain
Applications accepted all year round

Funding Type

PhD Type

Motor neurone disease is a progressive, fatal neurological disorder with no known cure. It is characterised by selective loss of motor neurons in the spinal cord and cortex.
  TDP-43 The Key protein for finding a cure for Motor Neurone Disease
  Dr S Antonyuk, Prof S Hasnain
Applications accepted all year round

Funding Type

PhD Type

Motor neurone disease is a progressive, fatal neurological disorder with no known cure. It is characterised by selective loss of motor neurons in the spinal cord and cortex.
  Understanding and dissecting microbial communities with Raman spectroscopy
  Prof R Goodacre
Applications accepted all year round

Funding Type

PhD Type

We have shown that it is possible to label bacteria with heavy isotopes of carbon (13C) and nitrogen (15N) and this incorporation within cellular biomass of heavy isotopes has led to significant shifts in certain vibrational modes from amino acids and nucleic acids that can be readily detected with Raman spectroscopy.
  Understanding molecular processes that control cell adhesion and migration
  Dr I Barsukov, Dr T Zech
Applications accepted all year round

Funding Type

PhD Type

Cells have an amazing ability to form complex tissues, differentiate and migrate. All these processes are controlled by a network of proteins that constantly change their activity and interactions in response to the environment.
  MSc by Research Programme: Bringing proteins together with small molecules
  Prof A Ciulli
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  Deciphering protective factors for intervertebral disc degeneration for mechanistic insights and intervention potentials
  Prof D Chan
Applications accepted all year round

Funding Type

PhD Type

Intervertebral disc degeneration (IDD) can lead to a diversity of problems including low back pain and sciatica as two very painful symptomatic outcomes.
  Bioinspired nanotopographies to control bacterial adhesion and biofilm formation
  Dr R D'Sa
Applications accepted all year round

Funding Type

PhD Type

By 2050, it is predicted that the rise of resistant strains of bacteria and the ever-growing threat of antimicrobial resistance (AMR) will be the cause of 10 million deaths annually, and will burden the global economy by £64 trillion.
  Broad spectrum antiviral and antibiofilm materials to treat hospital acquired infections
  Dr RA D'Sa
Application Deadline: 30 June 2020

Funding Type

PhD Type

Applications will close as soon as a suitable candidate is found.
  3D imaging technology roadmap and software tool for X-ray histology
  Research Group: Bioengineering
  Dr P Schneider
Application Deadline: 29 May 2020

Funding Type

PhD Type

Supervisor. Philipp Schneider, Philip Basford, Peter Lackie (Faculty of Medicine). Project description.
  Signal analysis and computer modelling of atrial fibrillation.
  Prof U Schotten
Applications accepted all year round

Funding Type

PhD Type

The successful candidate will develop an adaptive multi-scale 3D computer model of atrial fibrillation. The model will be built starting from an already existing 3D computer model developed in collaboration with other academic partners.
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