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The University of Manchester, Faculty of Biology, Medicine and Health Biophysics PhD Projects, Programs & Scholarships

We have 30 The University of Manchester, Faculty of Biology, Medicine and Health Biophysics PhD Projects, Programs & Scholarships

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  (A*STAR) The role of desmosome regulation in development, wound healing and cancer
  Dr C Ballestrem, Prof D R Garrod
Application Deadline: 31 January 2020

Funding Type

PhD Type

The regulation of cell movement is a key factor in human development and disease. Desmosomes are intercellular junctions that give strength to normal tissues by binding their cells tightly together.
  (BBSRC DTP CASE) Analysing the efficiency of protein secretion using Lattice Lightsheet Microscopy
  Prof V Allan, Prof M Lowe, Prof S Cartmell
Application Deadline: 31 January 2020

Funding Type

PhD Type

Protein-based biopharmaceuticals are of tremendous importance both for providing disease treatments, and for the UK economy. They are typically manufactured using mammalian host cells, but some are much harder to produce than others.
  (BBSRC DTP CASE) Jellyfish-collagen hydrogels for culture and differentiation of human mesenchymal stem cells and 3D cartilage bioprinting
  Dr J Bella, Dr S Richardson, Dr M Domingos
Application Deadline: 31 January 2020

Funding Type

PhD Type

We are looking for an enthusiastic and talented graduate from a relevant biomedical or materials science degree to develop next-generation, sustainable collagen-based scaffolds for stem cell culture, differentiation, and 3D bioprinting, aimed at tissue regeneration applications.
  (BBSRC DTP) Improving 3D X-ray Imaging of Live Cells and Soft Tissues
  Dr M Sherratt, Prof S Cartmell
Application Deadline: 31 January 2020

Funding Type

PhD Type

Clinical X-ray imaging in three dimensions (commonly referred to as a CT scan) is a key diagnostic tool. Micro-computed X-ray tomography (microCT) has the potential to image relatively large biological samples in 3D at sub-micron resolution.
  (BBSRC DTP) Plant-based production of a vaccine against gonorrhoea
  Prof J P Derrick, Dr A Day
Application Deadline: 31 January 2020

Funding Type

PhD Type

The sexually transmitted disease gonorrhoea is caused by the Gram-negative bacterium Neisseria gonorrhoeae. N. gonorrhoeae is a close relative of Neisseria meningitidis, which causes meningococcal meningitis.
  (BBSRC DTP) Predictive Genotype-Phenotype-Fitness Mapping in E.coli
  Dr M Lagator, Dr J-M Schwartz, Dr P Day
Application Deadline: 31 January 2020

Funding Type

PhD Type

Genotype-phenotype-fitness mapping, or the connection between genetic mutations and their effects on organismal fitness, lies at the heart of understanding and predicting evolution.
  (BBSRC DTP) Selective knockdown of proinflammatory microRNAs to tackle neurodegeneration and cognitive decline: myth or reality?
  Dr E Bichenkova, Prof J Neill, Dr F Roncaroli, Prof D Clarke
Application Deadline: 31 January 2020

Funding Type

PhD Type

Neurodegenerative diseases (e.g. multiple and amyotrophic lateral sclerosis, Alzheimer’s and Parkinson’s diseases) have tremendous psychological, clinical and social impact, which becomes increasingly challenging in the global trend of population aging.
  (BBSRC DTP) Stress reactivity and social loss: the effects of adverse childhood experiences on neurobiology throughout the lifespan
  Dr N Muhlert, Prof R Elliott
Application Deadline: 31 January 2020

Funding Type

PhD Type

We are living in an ageing population. Roughly one in five people in the UK is aged over 65. As people live longer there is an increasing need to discover factors that promote healthy ageing.
  (BBSRC DTP) The role of collagen VI in the skeletal muscle stem cell niche using combined imaging approaches including Cryo-EM
  Prof C Baldock, Prof G Cossu, Dr A Roseman
Application Deadline: 31 January 2020

Funding Type

PhD Type

Collagen VI is a unique member of the collagen superfamily which has a short collagenous region but arrays of globular domains and assembles to form beaded microfibrils.
  (BBSRC DTP) Uncovering the mechanism(s) responsible for a novel neurite co-orientation process
  Dr C Dobson, Prof Keith Crutcher, Dr T Brown, Prof R Baines
Application Deadline: 31 January 2020

Funding Type

PhD Type

How do neurons decide where to grow? Although there is evidence for the role of growth factors (diffusible or bound) as well as electrical activity, the specific mechanism remains elusive.
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