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The University of Manchester Biophysics PhD Projects, Programmes & Scholarships

We have 35 The University of Manchester Biophysics PhD Projects, Programmes & Scholarships

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Biological Sciences

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The University of Manchester

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We have 35 The University of Manchester Biophysics PhD Projects, Programmes & Scholarships

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Control of protein self assembly by biological ions

In addition to being an energy source in biological reactions, recent discoveries suggest adenosine triphosphate (ATP) also plays a critical role in maintaining cell stability and preventing deleterious cellular processes through modulating biomacromolecular self assembly. Read more

Development of peptide hydrogel as an anticancer drug carrier

Growth in nanotechnologies can now be exploited to enable engineering of new drug delivery systems for enhancing the entrapment of drugs in nano-sized structures with tailored physical properties to suit therapeutic need. Read more

Ambulatory monitoring of Raynaud’s phenomenon and systemic sclerosis associated microcirculation

Systemic sclerosis (SSc), a microvascular autoimmune disease, causes damage to the small blood vessels (microvasculature). Although rare it has the highest mortality of all rheumatological conditions and causes significant morbidity. Read more

Sunlight and skin type: exploring the vitamin D status of the black-skinned population in UK

  Research Group: Molecular Environmental Sciences
Vitamin D is necessary for calcium homeostasis, and thus a healthy musculoskeletal system. It is also implicated in contributing to defences against a range of other ailments including autoimmune diseases, respiratory tract infections and cancers. Read more

Wear and biological safety of dental titanium implants

Implant dentistry with a globally market of CHF 4.5 billion in 20181 has shown a steady increase over the last few years. Titanium implant is the most widely accepted and successfully used type of dental implant. Read more

Mutagenesis and DNA repair in persistent cells

Antimicrobial resistance is a global health problem and we need new approaches to mitigate it. When the microbial community is treated with a lethal concentration of the antibiotic, the surviving cells are either genetically resistant or antibiotic tolerant. Read more

The chemistry and biophysics of phosphoryl transfer enzymes

One of the most remarkable features of the chemistry of living organisms is the evolutionary utilisation of phosphate esters to provide biopolymers that encode genetic information, deliver temporal protein regulation, generate and distribute free energy throughout the cell, and to provide a ubiquitous handle for metabolic intermediates. Read more

Modelling photosynthetic water oxidation

This project aims use molecular modelling methods and spectroscopy to understand how the protein environment of electron transfer cofactors in photosysnthesis and in particular how the water oxidising complex, facilitates electron transfer and also helps stabilise these radical species to maintain a charge separated state. Read more

Method development and applications of Electron Paramagnetic Resonance (EPR)

Electron Paramagnetic Resonance (EPR) is a spectroscopic tool used to study systems containing unpaired electrons. EPR has wide ranging applications from materials science and quantum computing to structural biology and (bio)catalysis. Read more

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