We have 26 Newcastle University, Faculty of Medical Sciences PhD Projects, Programmes & Scholarships

Project Summary. This iCASE BBSRC DTP studentship provides an exciting opportunity to use a diverse range of cutting-edge techniques, and exploit the advantages of different model systems, to elucidate new cell signalling mechanisms that protect against ageing/age-associated diseases. Read more

Supervisors: Dr E A Veal, Prof P Eyers

15 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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BBSRC NLD Doctoral Training Partnership: How to resolve the big break-up: understanding the role of novel DNA damage repair mechanisms in Gram-positive bacteria

Newcastle University Faculty of Medical Sciences

By 2050, bacterial pathogens will be the foremost threat to human health due to the rise in antimicrobial resistance. For instance, Staphylococcus aureus is the leading Gram-positive bacterium causing death from bacterial infections worldwide and was accounted for killing around one million people in 2019. Read more

Supervisors: Dr C Winterhalter, Prof A Darby, Dr H Strahl von Schulten, Dr M Horsburgh

15 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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BBSRC NLD Doctoral Training Partnership: Conformational gymnastics of a large multi-domain enzyme through AI, computational and experimental approaches

Newcastle University Faculty of Medical Sciences

Background - Proteins carry out their cellular roles primarily through domains, which are the structural, functional and evolutionary units. Read more

Supervisors: Prof W Yue, Prof D Rigden

15 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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BBSRC NLD Doctoral Training Partnership: How can proteins sense micro-scale membrane topography?

Newcastle University Faculty of Medical Sciences

We are seeking a highly motivated student keen to do molecular cell biology research in a hitherto unexplored regulatory mechanism – how proteins (nanoscale) can sense microscale changes in cell membrane topography/shape? [1,2].The control of protein localisation at the cell membrane is key to cell signalling. Read more

Supervisors: Dr J Rodriguez, Dr A Wollman

15 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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BBSRC NLD Doctoral Training Partnership: Piercing the armour: C. difficile S-layer permeability

Newcastle University Faculty of Medical Sciences

Are you interested in a PhD studying antibiotic resistant bacteria and keen to develop your research skills in microbiology combined with computational and imaging methods? Do you want to understand how proteins work, their intricate structures and how they interact with metals?. Read more

Supervisors: Prof P Salgado, Dr A Bronowska, Dr K Djoko, Dr M Harkiolaki

15 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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BBSRC NLD Doctoral Training Partnership: Characterisation of physiological properties and pathogenic potential of Mycobacterium bovis L-forms

Newcastle University Faculty of Medical Sciences

This exciting project addresses aspects of antimicrobial resistance (AMR); one of the biggest issues facing humanity. Mycobacterium bovis (closely related to Mycobacterium tuberculosis) is a cause of tuberculosis disease affecting cattle, other farm and wild animals, as well as humans. Read more

Supervisors: Dr K Mickiewicz, Dr AB Brown, Dr J Kozyra

15 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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BBSRC NLD Doctoral Training Partnership: Trichomonas parasites bacterial-like bacteriocins: what role in Trichomonas-microbiota interactions?

Newcastle University Faculty of Medical Sciences

This project represents a unique opportunity to gain multidisciplinary skills integrating ‘omics (comparative and evolutionary genomics and transcriptomics)… Read more

Supervisors: Prof R Hirt, Dr A Jackson, Dr H Strahl von Schulten

15 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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BBSRC NLD Doctoral Training Partnership: Understanding and enhancing nuclear dynamics for microglial replacement therapy

Newcastle University Faculty of Medical Sciences

Microglia are the major immune cell of the brain playing a critical role the progression of age-related disorders such as Alzheimer’s disease (AD). Read more

Supervisors: Dr MJK Keogh, Prof M Collin, Dr I Karakesisoglou

15 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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BBSRC NLD Doctoral Training Partnership: Does age-associated stress tolerance in C. albicans promotes colonization and drives disease in a C. elegans model of infection?

Newcastle University Faculty of Medical Sciences

Human fungal pathogens are often described as ‘Hidden Killers’ as they kill more people every year than malaria and many other ‘super-bugs’ but are often overlooked. Read more

Supervisors: Dr A da Silva Dantas, Dr F Del Carratore, Dr E Veal

15 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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BBSRC NLD Doctoral Training Partnership: Critical evaluation of mitophagy, mitochondrial dysfunction and senescence axis

Newcastle University Faculty of Medical Sciences

Many types of cells become senescent as a response to a variety of stressors, and show distinct senescence phenotype such as persistent DNA damage, mitochondrial dysfunction, increased levels of reactive oxygen species (ROS) and pro-inflammatory cytokine. Read more

Supervisors: Dr S Miwa, Dr V Korolchuk, Prof A McArdle

15 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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BBSRC NLD Doctoral Training Partnership: Deciphering the role of transcriptional enhancers in developmental gene regulation

Newcastle University Faculty of Medical Sciences

Healthy cartilage in our joints is essential for us to maintain an active life into old age, with cartilage breakdown causing chronic pain, joint stiffness and reduced mobility. Chondrocytes, the only cell type present in cartilage, have a specialised phenotype that is initiated during development and then maintained throughout our lives. Read more

Supervisors: Dr L Reynard, Prof G Bou-Gharios, Prof D Young, Dr M Papamichos Chronakis

15 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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BBSRC NLD Doctoral Training Partnership: Dissecting Gram-negative envelope biogenesis to understand drug delivery in Gram-negative pathogens

Newcastle University Faculty of Medical Sciences

Background. Much of the ecological success of bacteria can be attributed to their robust, protective envelope. The cell envelope is a complex structure, featuring a mesh-like peptidoglycan (PG) layer that provides mechanical protection to the cell. Read more

Supervisors: Dr M Banzhaf, Dr K Djoko, Dr H Strahl von Schulten

15 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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BBSRC NLD Doctoral Training Partnership: Bartering essential nutrients in animal-microbe symbiosis

Newcastle University Faculty of Medical Sciences

All human and animal life exists in symbiosis with a complex microbiota. To improve understanding of how animals perform, survive, interact with, and adapt to, the natural world, we need to understand the fundamental basis of the relationships between animals and microbes. Read more

Supervisors: Prof D Thwaites, Prof G Hurst, Dr C Anderson

15 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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BBSRC NLD Doctoral Training Partnership: Investigating the mechanism of mucin degradation by a key member of the human gut microbiota

Newcastle University Faculty of Medical Sciences

The human gut microbiota is closely associated with health, development and disease. The thick mucus layer in the colon is the key barrier between the contents of the lumen and the epithelial cells, providing protection against potential pathogens and environmental insults. Read more

Supervisors: Dr D Bolam, Prof D Rigden, Dr J Marles-Wright

15 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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BBSRC NLD Doctoral Training Partnership: Insect-inspired pattern recognition with low computing power

Newcastle University Faculty of Medical Sciences

Bees have miniature brains compared to humans, but manage to perform impressive feats of visual behaviour. They can learn concepts, discriminate complex patterns and assess quantities. Read more

Supervisors: Dr V Nityananda, Prof J Marshall

15 January 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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We have 26 Newcastle University, Faculty of Medical Sciences PhD Projects, Programmes & Scholarships

Newcastle University, Faculty of Medical Sciences PhD Projects, Programmes & Scholarships

We have 26 Newcastle University, Faculty of Medical Sciences PhD Projects, Programmes & Scholarships

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