Bioinformatics (english language) PhD Projects, Programmes & Scholarships

We have 85 Bioinformatics (english language) PhD Projects, Programmes & Scholarships

Experimental and computational Cancer PhD: Overcoming osteosarcoma chemoresistance by characterizing and targeting cellular quiescence

University College London UCL Cancer Institute

Cancer is the leading cause of death in children and the second in young adults in England and Wales. Sarcomas, tumours that originate from connective tissues (bone, muscle, fat), account for around 15% of childhood cancers. Read more

Supervisors: Dr M Secrier, Dr L Cottone

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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The effect of early-life stress on cardiac function in later life

University of Dundee School of Medicine

Stressful experiences in early childhood can increase the risk of cardiovascular disease (CVD) in later life. How early-life stress (ELS) influences susceptibility to CVD onset remains largely unknown. Read more

Supervisors: Dr N Fraser, Dr C Murdoch, Prof T Hales

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Utility of in silico prediction tools to aid variant interpretation

University of Dundee School of Medicine

Accurate variant interpretation represents is essential for the successful implementation of genetic testing in the clinical setting. Read more

Supervisor: Dr P Newey

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Targeting the extracellular matrix remodelling for the treatment of obesity-associated cardio-renal dysfunction

University of Dundee School of Medicine

Obesity is a risk factor for many chronic metabolic diseases including heart failure and chronic kidney disease. Our lab demonstrated a tight association between increased deposition of extracellular matrix components (e.g. Read more

Supervisors: Dr L Kang, Dr C Murdoch

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

University of Dundee School of Life Sciences

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Supervisors: Prof G Sapkota, Dr S Virdee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Control and inhibition of virus replication

University of Leeds Faculty of Biological Sciences

The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specifically Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets. Read more

Supervisor: Dr A.K Tuplin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigation of host-virus interactions

University of Leeds Faculty of Biological Sciences

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25 in the area of molecular virology. Read more

Supervisors: Dr M Stacey, Dr J N Barr

Year round applications PhD Research Project Self-Funded PhD Students Only

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Machine Learning and Molecular Modelling in Mass Spectrometry

University of Leeds Faculty of Biological Sciences

This PhD project will harness the power of computational modelling and machine learning (A.I.) to analyse data obtained by mass spectrometry experiments and predict structural characteristics of biomolecules and their interactions. Read more

Supervisors: Prof F. Sobott, Dr A Kalli, Dr H Wang

Year round applications PhD Research Project Self-Funded PhD Students Only

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Manipulation of neuroimmune responses and behaviour by infectious agents

University of Leeds Faculty of Biological Sciences

This project is available exclusively to self-funded students who wish to commence study for a PhD in the academic year 2023/24. The project focuses on how infectious agents modify the individuals that they infect and how neuroimmune responses to infection moderate behaviour changes in warm-blooded animals and humans. Read more

Supervisors: Dr G Mcconkey, Dr S Clapcote

Year round applications PhD Research Project Self-Funded PhD Students Only

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Elucidating the molecular mechanisms of intrinsic antibiotic resistance in bacterial pathogens

University of Leeds Faculty of Biological Sciences

Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to the average human lifespan. Read more

Supervisor: Prof A O'Neill

Year round applications PhD Research Project Self-Funded PhD Students Only

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Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas

University of Leeds Faculty of Biological Sciences

V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas. Read more

Supervisor: Dr J Boyes

Year round applications PhD Research Project Self-Funded PhD Students Only

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PhD studentship in Population Health Sciences: Developing machine learning models for integration of molecular and clinical data

Newcastle University Population Health Sciences Institute

Award summary . 100% tuition fees (paid at home rate) and a minimum annual stipend of £19,237 (2024/2025) with support for research costs. Read more

Supervisor: Dr J Nsengimana

17 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia susceptibility using model systems

University of Leeds Faculty of Medicine and Health

Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more

Supervisors: Prof P Hopkins, Dr M-A Shaw, Dr C Diggle

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

University of Leeds Faculty of Medicine and Health

The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more

Supervisors: Dr G Mavria, Dr S Bell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic reprogramming of immune cells; novel mechanism for drug resistance in leukaemia

University of Leeds Faculty of Medicine and Health

Under pathogenic challenges, cells of the haematopoietic system become epigenetically reprogrammed and establish immune memory. Read more

Supervisor: Dr P Laslo

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 85 Bioinformatics (english language) PhD Projects, Programmes & Scholarships

Bioinformatics (english language) PhD Projects, Programmes & Scholarships

We have 85 Bioinformatics (english language) PhD Projects, Programmes & Scholarships

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