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We have 44 Bioinformatics (functional) PhD Projects, Programmes & Scholarships

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Bioinformatics (functional) PhD Projects, Programmes & Scholarships

We have 44 Bioinformatics (functional) PhD Projects, Programmes & Scholarships

Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia susceptibility using model systems

Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more

Common genetic origins of visual and neurocognitive disorders

There is emerging evidence that apparently distinct neurodegenerative diseases have common genetic origins. For example, genes such as ARMS2 and HTRA1, which are fundamental to regulating neuronal health, are implicated in both dementia and diseases of the retina (particularly age-related macular degeneration). Read more

Engineering more water-use efficient crops: functional genomics of CO2 fixation during Crassulacean acid metabolism

The world is getting hotter and drier due to climate change, and the human population is growing rapidly. Furthermore, it has been predicted that we will need to increase crop yields by 50 - 70 % by 2050 in order to feed the predicted 9 - 10 billion people. Read more

Cardiac Harmony: Modelling Heart Beats with Stem Cells and Code

Despite significant advancements in cardiac research, heart disease remains a leading cause of mortality globally. Unexpected cardiac events can occur even in young, fit individuals engaged in routine activities. Read more

Genetics: Investigating the molecular basis of optic nerve degeneration in glaucoma to try and develop a personalized medicine strategy for treatment

The optic nerve is a special sensory nerve that transmits visual impulses from the retina to the brain. Primary Open Angle Glaucoma (POAG) is a chronic, progressive optic neuropathy of multifactorial origin that affects 1 in 10 elderly individuals. Read more

Genetics: Genetic studies of developmental eye disorders to investigate genotype-phenotype correlations

Developmental eye defects that affect the front of the eye give rise to a spectrum of congenital ocular phenotypes that affect the cornea, lens, iris, trabecular meshwork or the globe itself. Read more

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