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Biotechnology (recombinant) PhD Projects, Programs & Scholarships

We have 22 Biotechnology (recombinant) PhD Projects, Programs & Scholarships

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  Modelling cellular stress during recombinant protein production for improving upstream biomanufacturing processes
  Dr D Dikicioglu, Prof G Lye
Application Deadline: 29 November 2019

Funding Type

PhD Type

Applications are invited for one PhD studentship to work in modelling the stress imposed on host organisms by recombinant protein production for improving predictive capabilities of upstream bioprocess models employed in biomanufacturing practices.
  Oxidative protein folding of industrially and pharmaceutically important recombinant proteins
  Dr H Lu, Dr A Day
Applications accepted all year round

Funding Type

PhD Type

Oxidative protein folding is an important process for the function of many proteins, which includes both folding and formation of native disulphide bonds.
  Developing a virus-like particle (VLP) Polio vaccine
  Dr G Mulley
Applications accepted all year round

Funding Type

PhD Type

Rationale. Poliovirus is a non-enveloped RNA virus, spread via the faecal-oral route, that causes the infectious disease Poliomyelitis (Polio).
  (BBSRC DTP) Engineering novel stress-resilient microalgae strains as improved platform strains for industrial biotechnology
  Dr J Pittman, Dr P Gallois, Dr A Day
Application Deadline: 31 January 2020

Funding Type

PhD Type

Microalgae have potential as photosynthetic cell factories for the production of chemicals and metabolites that can be used for industrial applications or as platform strains for the production of recombinant proteins.
  EASTBIO: Understanding the pathogenesis of life-threatening Burkholderia cenocepacia infections using blocking antibodies and novel chemistry scaffolds to untangle complex aspects of AMR
  Prof A Porter, Dr S Palliyil, Prof M Jaspars
Application Deadline: 5 January 2020

Funding Type

PhD Type

Supervisors. Professor Andy Porter (University of Aberdeen). https://www.abdn.ac.uk/people/a.porter. Dr Soumya Palliyil (University of Aberdeen).
  Antibody-drug conjugates (ADCs) for the treatment of solid tumours
  Dr S Karagiannis, Prof J Downward
Application Deadline: 29 November 2019

Funding Type

PhD Type

An Antibody-Drug Conjugate (ADC) comprises an antibody targeted toward a tumour cell surface antigen, coupled through a chemical linker to a highly-cytotoxic drug.
  Development of nature-inspired polyester particles for cancer vaccines
  Prof Bernd Rehm
Applications accepted all year round

Funding Type

PhD Type

Advances in synthetic biology allows recombinant bacteria to produce protein coated polyester particles. These polyester particles have been utilized as particulate vaccines against bacterial and viral infections.
  (BBSRC DTP) Mechanism of early steps in protein synthesis by cryoEM imaging of supramolecular complexes
  Dr A Roseman, Prof G D Pavitt, Prof C Baldock
Application Deadline: 31 January 2020

Funding Type

PhD Type

The aim of this project is to understand the mechanism and control of protein synthesis in eukaryotic cells at the molecular level, particularly focused around the role of the eukaryotic translation initiation factors eIF2, eIF5 and eIF2B.
  (BBSRC DTP) Understanding structure and function of the mechanosensors talin and vinculin
  Dr C Ballestrem, Prof C Baldock, Dr A Roseman
Application Deadline: 31 January 2020

Funding Type

PhD Type

The ability of cells to sense biochemical and mechanical properties of their extracellular matrix (ECM) environment is critical for the development of functional tissue.
  Protease-resistant antimicrobial peptides to target bacterial and fungal pathogens
  Dr J Bella, Dr L Tabernero
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance is quickly becoming a serious global health problem. The emergence of multidrug-resistant microbial strains combined with the drying up of the antibiotic pipeline in the pharmaceutical industry has significantly worsened the situation in recent years.
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