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We have 59 Bioinformatics (sequencing) PhD Projects, Programmes & Scholarships

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Bioinformatics (sequencing) PhD Projects, Programmes & Scholarships

We have 59 Bioinformatics (sequencing) PhD Projects, Programmes & Scholarships

Genetics: Investigating the molecular basis of optic nerve degeneration in glaucoma to try and develop a personalized medicine strategy for treatment

The optic nerve is a special sensory nerve that transmits visual impulses from the retina to the brain. Primary Open Angle Glaucoma (POAG) is a chronic, progressive optic neuropathy of multifactorial origin that affects 1 in 10 elderly individuals. Read more

Genetics: Genetic studies of developmental eye disorders to investigate genotype-phenotype correlations

Developmental eye defects that affect the front of the eye give rise to a spectrum of congenital ocular phenotypes that affect the cornea, lens, iris, trabecular meshwork or the globe itself. Read more

The Evolution of Vision in Mosquitoes

Background . Due to their capacity to transmit viruses such as Zika and parasites like Plasmodium (the causative agent of malaria), mosquitos are regarded by the World Health Organization as one of the most lethal organisms on our planet (WHO | Global vector control response 2017–2030, 2020). Read more

Understanding the role of mucin genetic variation in lung disease

  Research Group: Human & Medical Genetics
Understanding how genetic variation contributes to lung diseases is important in understanding how the disease develops and identifying potential molecular targets for therapy. Read more

Finding the cause of familial facial (Bell’s) palsy

The facial (VII) cranial nerve controls the muscles of facial expression, supplies taste sensation to parts of the tongue and controls a small muscle connected to the ear drum. Bell’s palsy is the clinical condition in which there is impaired function of the facial nerve, associated with facial muscle weakness. Read more

Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more

Pulling the plug on antimicrobial resistance – novel antimicrobial compounds from The Roman Baths hot spring (Bath, UK)

Applications are invited for a three-year PhD studentship. The studentship will start on 1st October 2024. Project Description. Antimicrobial resistance (AMR) in bacterial, fungal and protozoan pathogens is a globally recognised threat to the treatment of infectious diseases. Read more

Developing synthetic microbial communities for the control of pea downy mildew

Demand for food production is increasing due to growing global population, reduced land availability for agriculture, concern over the effects of the environment on agriculture, and decreasing yield reliability because of climate change. Read more

PhD in stem cell modelling for neuropsychiatric disorders

This project provides a unique opportunity to explore the developmental origins of schizophrenia—a severe mental health disorder—using cutting-edge patient-derived stem cell models. Read more

Genetic causes of novel neurodevelopmental disorders

The Rare Disorder Genetics / Bicknell lab is interested in characterising novel genetic syndromes, with three core motivations. -the difference we can make to families with rare disorders, through providing them with more information. Read more

Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more

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