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We have 5 Bioinformatics (2013) PhD Projects, Programmes & Scholarships

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Bioinformatics (2013) PhD Projects, Programmes & Scholarships

We have 5 Bioinformatics (2013) PhD Projects, Programmes & Scholarships

Short and long-term genetic and behavioural consequences of traumatic brain injury in fruit flies

General background . How many fingers am I holding up? What day of the week is it? Follow my finger? These three questions are designed to test your sensory, memory and motor neural abilities following an accident; all three systems are affected by a severe deceleration of your brain. Read more

In silico modelling of endocannabinoid evolution

In the brain, the endocannabinoid (eCB) system maintains adequate neurotransmission (Lu and Mackie 2016). Indeed, the eCB system provides a negative feedback mechanism, preventing over-activation of synaptic transmission. Read more

Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more

Clinical Gastroenterology: The regulation of GDH expression in Clostridioides difficile

Clostridioides difficile infection (CDI), the most common cause of infective antibiotic-associated diarrhea in the western world, is diagnosed by a combination of tests that firstly detect the organism, then the toxins that it produces (Planche 2013). Read more

Cancer: Inhibiting cell metabolism to enhance tumour cell death

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more
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