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Biotechnology (complex systems) PhD Projects, Programs & Scholarships

We have 33 Biotechnology (complex systems) PhD Projects, Programs & Scholarships

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  Scholarships available for SECReT: The International Training Centre for Security and Crime Related Research Degrees

Funding Type

PhD Type

UCL SECReT is the international centre for training in security and crime related research degrees, the first centre of its kind in Europe.
  EastBio Understanding the Structural Basis of Encapsulin Assembly for Efficient Engineering of Encapsulated Enzymes
  Dr D Clarke
Application Deadline: 5 January 2020

Funding Type

PhD Type

Co-Supervisors. Dr Stephen Wallace, School of Biological Sciences, University of Edinburgh. Dr. Louise Horsfall, School of Biological Sciences, University of Edinburgh.
  Integrated mathematical modelling and experimental research into interactions between microorganisms
  Dr J U Kreft
Applications accepted all year round

Funding Type

PhD Type

Our group aims to combine theoretical & experimental approaches to understand major problems in the ecology and evolution of microbes.
  Design of 3D printed microfluidic systems with engineered hydrogels for organ-on-chip applications
  Dr J Gautrot
Application Deadline: 31 January 2020

Funding Type

PhD Type

A studentship in the design of 3D printed microfluidic systems with engineered hydrogels for organ-on-chip applications is available in the group of Prof J.
  (BBSRC DTP) Optimisation of heteromeric protein complex formation via co-ordinated mRNA localisation
  Prof M Ashe, Dr M Pool, Prof C M Grant
Application Deadline: 31 January 2020

Funding Type

PhD Type

RNA granules play key roles in cells controlling many aspects of mRNA fate. For instance, in response to stress the relocalisation of mRNAs to mRNA processing bodies (P-bodies) and stress granules facilitates the degradation or storage of unwanted or valuable mRNAs, respectively.
  Precision Medicine DTP – A novel data integration method for cellular social networks within self-organising multicellular systems
  Research Group: Institute of Stem Cell Research
  Dr G Blin, Dr L Schumacher, Dr A Tsanas
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. The quantification and interrogation of how the cells organise and interact with their environment is fundamental for advancing developmental biology, cancer research, pharmaceutics and medical diagnostics.
  EASTBIO Unravelling mechanisms controlling gene expression noise in S. cerevisiae during rapid adaptive responses and its application to biotechnology.
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Dr S Granneman
Application Deadline: 5 January 2020

Funding Type

PhD Type

Microbes are constantly subjected to changes in their environment and have to rapidly alter their transcriptome to adapt efficiently.
  Unravelling mechanisms controlling gene expression noise in S. cerevisiae during rapid adaptive responses and its application to biotechnology.
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Dr S Granneman, Prof P Swain
Application Deadline: 5 January 2020

Funding Type

PhD Type

Microbes are constantly subjected to changes in their environment and have to rapidly alter their transcriptome to adapt efficiently.
  EASTBIO Multiscale modelling and analysis of stochastic gene expression in mammalian cells
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Dr R Grima, Dr D Oyarzun
Application Deadline: 5 January 2020

Funding Type

PhD Type

We are looking for a motivated doctoral student to join us on an exciting project at the interface of stochastic modelling and systems and synthetic biology.
  Forward engineering of pattern formation: Models and experiments towards predictive multicellular self-organisation
  Research Group: Institute of Stem Cell Research
  Dr G Blin
Application Deadline: 5 January 2020

Funding Type

PhD Type

Background. The aim of developmental biology is a complete understanding of how the embryo develops, how embryonic cells acquire their fate and how they arrange in time and space to create complex organisms.
  EPSRC CDT in Bioprocess Engineering Leadership: Complex Biological Products Manufacture

Funding Type

PhD Type

Biological products and their manufacture are progressing to unparalleled levels of complexity. Examples include engineered biocatalysts, antibody-drug conjugates, multivalent vaccines and cellular therapies.
  Development of ex vivo tissue culture models for developing next-generation biomaterial scaffolds for acellular regenerative medicine.
  Prof I Gibson, Prof N Vargesson
Applications accepted all year round

Funding Type

PhD Type

Bone repair and regeneration can be influenced by various guidance cues, including pharmacological cues, hypoxia environment and chemical cues released from scaffolds [1-3].
  EASTBIO A synthetic biology approach to design ‘intelligent’ organoids for the study of host-microbe interactions
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Dr E Cachat, Dr L Boulter
Application Deadline: 5 January 2020

Funding Type

PhD Type

Organoids are self-organised, 3D structures generated in vitro from adult or pluripotent stem cells, that exhibit similar functionality as their tissue of origin.
  EASTBIO Forward engineering of pattern formation: Models and experiments towards predictive multicellular self-organisation
  Research Group: Institute of Stem Cell Research
  Dr G Blin, Dr L Schumacher
Application Deadline: 5 January 2020

Funding Type

PhD Type

Background. The aim of developmental biology is a complete understanding of how the embryo develops, how embryonic cells acquire their fate and how they arrange in time and space to create complex organisms.
  EASTBIO Single cell multi-omics profiling of the brain for the study of neurological disease
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Dr C Sibley
Application Deadline: 5 January 2020

Funding Type

PhD Type

Second Supervisor. Emily Osterweil, CMVM University of Edinburgh. Recent research emphasises that neurological diseases involve a complex interplay of cell autonomous and non-cell autonomous events mediated by the different cell types in the brain (e.g.1).
  Nanotribological properties of organic surfaces
  Prof GJ Leggett
Applications accepted all year round

Funding Type

PhD Type

Friction is ubiquitous in all sliding contacts. Much energy is dissipated in sliding contacts, and the minimisation of friction can make a significant contribution to the efficient use of fuels.
  Hybrid dynamic modelling framework for bioprocess digitalisation and optimisation
  Dr D Zhang
Application Deadline: 30 August 2020

Funding Type

PhD Type

The background of this research is to explore and integrate a range of mechanistic and machine learning based modelling strategies to develop a multilevel digital framework (digital twin) for industrial bioprocess dynamic simulation and prediction, online optimisation (online learning), and product quality control.
  Multiscale dynamic visualisation framework for industrial mutants design and biological knowledge discovery
  Dr D Zhang
Application Deadline: 30 August 2020

Funding Type

PhD Type

Current industrial bio-production processes exclusively uses yeast and bacteria as the microorganism hosts to synthesise valuable commercial compounds.
  Control of antibiotic production through synthetic biology of bacterial hormone signalling
  Prof E Takano, Prof R Breitling
Applications accepted all year round

Funding Type

PhD Type

There is an urgent need for new antibiotics due to an increase in antibiotic resistance. To produce these essential drugs efficiently in biotechnological systems, we need to have a better understanding of the regulatory mechanisms of antibiotic production.
  Partitioning primary and secondary changes of gene expression caused by gene mutations
  Dr D Talavera, Prof G D Pavitt, Dr J-M Schwartz
Applications accepted all year round

Funding Type

PhD Type

Control of gene expression is a complex cell process, which involves balancing both the synthesis and the degradation of RNA and protein so as to establish optimal levels of each protein.
  New Process Analytical Technology (PAT) and Downstream Processing (DSP) for the manufacture of in vitro transcribed mRNA
  Prof O Thomas
Application Deadline: 31 January 2020

Funding Type

PhD Type

A fully funded 4 year BBSRC/Astra Zeneca PhD studentship is available in the School of Chemical Engineering at the University of Birmingham, starting in October 2020.
  Advancing engineering and gene circuits approaches to regulate metabolism in productive, fast-growing cyanobacterial strains
  Research Group: Institute of Molecular Plant Sciences
  Dr A McCormick, Dr Baojun Wang
Application Deadline: 5 January 2020

Funding Type

PhD Type

Cyanobacteria are an important phylum of photosynthetic microbes that can convert captured CO2 into a wide variety of complex organic molecules.
  Neuropeptide Research - PhD Opportunity at a World Class Institution
  Assoc Prof M Muttenthaler, Assoc Prof I Vetter
Applications accepted all year round

Funding Type

PhD Type

We are seeking talented and highly motivated PhD candidates for the following multidisciplinary project. Neuropeptides are key mediators in many biological functions and understanding their interaction with target proteins is fundamental to unravel the underlying mechanism of diseases.
  Developing mass spectrometry tools to characterise algae’s highly efficient macromolecular machines
  Dr A Leney, Prof H J Cooper
Application Deadline: 12 January 2020

Funding Type

PhD Type

Microalgae are one of the oldest lifeforms on the planet and can survive in extreme climates such as on ocean floors/mountain lakes.
  Understanding and Engineering E. coli biofilm formation
  Dr T Overton
Application Deadline: 12 January 2020

Funding Type

PhD Type

Biofilms are communities of bacteria living together, bound by a self-produced extracellular matrix, often attached to a solid surface (Hall-Stoodley et al., 2004).
  Engineering de novo microscopic ecologies to monitor and dissect disease spread
  Dr T Gorochowski, Dr S English
Application Deadline: 6 January 2020

Funding Type

PhD Type

Understanding what regulates the spread of diseases in space and time is critical if we are to combat them effectively.
  MRC DTP 4 Year PhD Programme: Deciphering the role of oxidative stress in cardiovascular disease using physiological and 3D cell models.
  Dr C Murdoch, Dr C Henderson
Application Deadline: 11 January 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  Synthetic biology-enabled new generation biosensors to tackle global health and environmental challenges
  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
  Dr Baojun Wang
Application Deadline: 5 January 2020

Funding Type

PhD Type

The traditional laboratory-based analytical assays for disease biomarkers and environmental toxins are expensive, time consuming and normally require specialised personnel and complex equipment.
  Precision Medicine DTP - A step change in sensitivity of Raman spectroscopy for accurate and rapid analysis of living cells
  Dr A Downes, Dr H Yin
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Most methods of cell characterization require a destructive or invasive test, without any real-time readout.
  The role of serotonin in crayfish anti-predatory behaviour and dominance
  Dr T Breithaupt
Application Deadline: 29 January 2020

Funding Type

PhD Type

Serotonin is involved in anxiety-like behaviour as well as in dominance fights in crayfish. Anxiety-like behaviour can be elicited by a stressful experience such as exposure to chemical predation cues or intraspecific fight experience.
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