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Biotechnology (information studies) PhD Projects, Programs & Scholarships

We have 62 Biotechnology (information studies) PhD Projects, Programs & Scholarships

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  Expanding the utility of DNA methylation profiles in peripheral tissues using captured biological variation
  Dr M Suderman
Application Deadline: 25 November 2019

Funding Type

PhD Type

Medicine has benefited from the use of molecular biomarkers for estimating health risks, diagnosing disease, selecting treatments and predicting treatment response.
  Bioinformatics studies of protein structures, functions and their interactions
  Dr L J McGuffin
Applications accepted all year round

Funding Type

PhD Type

The computational study of protein structures, functions and their interactions is fundamental to our understanding of disease.
  Metabolic rewiring in liver cancer: Role of oxidative stress and the Nrf2 pathway
  Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

Many of the major risks factors for developing liver cancer such as alcohol, obesity, smoking and toxin exposure share in common a role for oxidative stress.
  Predicting the development of oral cancer
  Dr C Darido
Applications accepted all year round

Funding Type

PhD Type

Human head and neck cancer is a devastating disease with poor survival rates.
  From Structure-Function Studies to High Phytase Crops (HEMMINGSU20DTP)
  Dr A M Hemmings, Prof W Harwood
Application Deadline: 25 November 2019

Funding Type

PhD Type

Phytic acid is the major source of inorganic phosphate needed for growth found in the grains, oil seeds and beans of common animal feeds.
  An exploration of the links between mitochondrial function and splicing regulation. PhD in Medical Studies (SWBio DTP)
  Dr L Harries
Application Deadline: 2 December 2019

Funding Type

PhD Type

Lead Supervisor. Professor Lorna Harries, College of Medicine and Health, University of Exeter. Additional Supervisors. - Professor Mark Lindsay, Department of Pharmacy and Pharmacology, University of Bath.
  Oxidative protein folding of industrially and pharmaceutically important recombinant proteins
  Dr H Lu, Dr A Day
Applications accepted all year round

Funding Type

PhD Type

Oxidative protein folding is an important process for the function of many proteins, which includes both folding and formation of native disulphide bonds.
  4-year PhD in Genetic Epidemiology: The intergenerational transmission of health
  Dr N Davies
Application Deadline: 13 December 2019

Funding Type

PhD Type

We are offering an exciting 4-year PhD studentship* for candidates interested in discovering how health and wellbeing are transmitted across generations within families.
  Precision Medicine DTP - Modelling Sex Dependent Differences in Human Liver Disease using Stem Cell Derived Models and Organ on a Chip Devices
  Research Group: MRC Centre for Regenerative Medicine
  Dr D Hay, Prof P Saunders
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Metabolic syndrome is a cluster of conditions, which include increased blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels.
  Defining a novel assembly pathway in ssRNA viruses using X-ray footprinting.
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

Project co-supervised by Prof. Peter Stockley at Leeds and Prof. Reidun Twarock at University of York, as part of the White Rose network "Structural and Mechanistic Biology at the RNA/Ligand Interface".
  Decoding the genetic architecture of inflammatory arthritis at the single-cell level #RACE5
  Dr S Sansom, Prof P Bowness, Dr L Jostins-Dean, Prof K Raza
Application Deadline: 10 January 2020

Funding Type

PhD Type

Supervisors. Dr Stephen Sansom, Professor Paul Bowness, Dr Luke Jostins-Dean and Professor Karim Raza. Genome wide association studies (GWAS) of inflammatory arthritis have now revealed hundreds of genetic variants that are linked to different forms of inflammatory arthritis.
  Fueling chemotherapy resistance in triple-negative breast cancer
  Dr K Brown
Applications accepted all year round

Funding Type

PhD Type

Triple-negative breast cancer (TNBC) is a molecularly heterogeneous group of diseases defined by the lack of estrogen receptor (ER), progesterone receptor (PR) and absence of human epidermal growth factor receptor-2 (HER2) amplification.
  Understanding how altered GABA signalling in the brain’s master clock contributes to circadian rhythm disruption in Alzheimer’s disease. PhD in Medical Studies (MRC GW4 BioMed DTP)
  Dr M Belle
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr Mino Belle, Institute of Biomedical and Clinical Science, Medical School, University of Exeter. Dr James Hodge, Faculty of Life Sciences, University of Bristol.
  Investigation of a probiotic strain of Lactobacillus plantarum 2025 and the development of novel antibacterials
  Prof A Karlyshev
Applications accepted all year round

Funding Type

PhD Type

Background. The rise of multidrug resistant forms of microbial pathogens imposes a serious problem to public health worldwide. The rapid spread of antimicrobial resistance is associated with misuse of conventional antibiotics.
  MRC DiMeN Doctoral Training Partnership: Using wearable technology to identify activity and sleep patterns in inpatients with delirium and Parkinson’s disease
  Dr R Lawson, Dr S Del Din, Dr A Yarnall, Dr J Shi
Application Deadline: 6 January 2020

Funding Type

PhD Type

We are offering an enthusiastic and motivated PhD student the exciting opportunity to join our international renowned team.
  SWBio DTP PhD project: Amyloid Transcription Block Survival - Deriving Functionally Active Peptide Inhibitors of Amyloidosis and Toxicity
  Prof J Mason
Application Deadline: 2 December 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the South West Biosciences Doctoral Training Partnership (SWBio DTP).
  Chemical biology meets microbiology to combat climate change (GATESU20DTP)
  Dr A Gates, Dr Z Waller
Application Deadline: 25 November 2019

Funding Type

PhD Type

As well as carbon dioxide (CO2), other important climate-active gases are known to drive global warming. Importantly, nitrous oxide (N2O), is a greenhouse gas with 300-times greater global warming power than CO2 and it also contributes to the destruction of the ozone layer.
  Precision Medicine DTP - A personalised automatic approach for assessing and modelling the brain deep tissue waste drainage related structures
  Research Group: Centre for Clinical Brain Sciences
  Dr M Valdes Hernandez, Prof J Wardlaw, Dr M Bernabeu
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Previous experiments (Kress 2014) have suggested that brain features known as perivascular spaces play an important role in the clearance of metabolic waste from the brain tissue.
  Investigating the requirements of pro-inflammatory signaling in skin and head & neck Squamous Cell Carcinomas
  Dr C Darido
Applications accepted all year round

Funding Type

PhD Type

Squamous cell carcinomas (SCC) are amongst the most common cancer types afflicting man. SCCs most frequently arise from stratified squamous epithelia such as the epidermis or the mucosae of the head and neck.
  Mechanisms of regulating gene expression via selective mRNA transport
  Dr V Wickramasinghe, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

A critical step in the gene expression pathway that is altered in cancer is nuclear export of mRNA. We have demonstrated that mRNA export is not constitutive, but highly selective and can regulate distinct biological processes through poorly understood mechanisms.
  Unravelling the oncogenic activities of serum- and glucocorticoid-regulated kinase 1 (SGK1)
  Dr K Brown
Applications accepted all year round

Funding Type

PhD Type

The phosphoinositide 3-kinase (PI3K) pathway is a master regulator of numerous cellular phenotypes associated with cancer including cell survival, proliferation, growth, altered metabolism and malignant transformation.
  Immune cell re-programming as a therapy for lung disease. PhD in Medical Studies (GW4 BioMed MRC DTP)
  Dr C J Scotton
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr Chris Scotton, Institute of Biomedical & Clinical Science College of Medicine & Health, University of Exeter.
  Interplay between the translation of upstream open reading frames and ribosome nascent chain-associated factors to control gene expression in eukaryotic cells
  Dr M Pool, Prof G D Pavitt
Applications accepted all year round

Funding Type

PhD Type

Eukaryotic mRNAs typically contain one open reading frame that is translated into protein. However many mRNAs contain additional upstream ORFs (uORFs) that regulate protein expression by controlling the flow of ribosomes to the main ORF, often by regulated reinitiation.
  Therapeutic potential of microRNAs in medullary thyroid carcinoma
  Prof G. Hutvagner
Applications accepted all year round

Funding Type

PhD Type

The Project. Medullary thyroid cancer is a rare, aggressive neuroendocrine tumour. Treatment of MTC poses a major challenge due to its propensity of early metastasis and no available adjuvant systemic treatment options.
  The chemistry and biophysics of phosphoryl transfer enzymes
  Prof J Waltho, Dr A Almond
Applications accepted all year round

Funding Type

PhD Type

One of the most remarkable features of the chemistry of living organisms is the evolutionary utilisation of phosphate esters to provide biopolymers that encode genetic information, deliver temporal protein regulation, generate and distribute free energy throughout the cell, and to provide a ubiquitous handle for metabolic intermediates.
  SWBio DTP PhD project: Investigating the interplay of 3D chromosome structure and non-coding RNAs in plant defence
  Dr H-W Nützmann, Prof L D Hurst, Dr K Vance
Application Deadline: 2 December 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the South West Biosciences Doctoral Training Partnership (SWBio DTP).
  SWBio DTP PhD project: Automated T-cell expansion in an integrated bioelectronics microfluidic chip: paving the way for personalised T-cell therapies for blood cancer
  Dr M Di Lorenzo
Application Deadline: 2 December 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the South West Biosciences Doctoral Training Partnership (SWBio DTP).
  Integrated mathematical modelling and experimental research into interactions between microorganisms
  Dr J U Kreft
Applications accepted all year round

Funding Type

PhD Type

Our group aims to combine theoretical & experimental approaches to understand major problems in the ecology and evolution of microbes.
  Post-translational regulation of transcription dynamics in plant immunity
  Research Group: Institute of Molecular Plant Sciences
  Dr S Spoel, Dr E Bayne
Application Deadline: 5 January 2020

Funding Type

PhD Type

Precise regulation of gene transcription is vital for all organisms. In eukaryotes, dynamic changes in gene transcription orchestrate cell development and cellular responses to the ever changing environment.
  Understanding the neural coding of touch as enabling technology for prosthetics and robotics.
  Dr R Dahiya
Application Deadline: 21 November 2019

Funding Type

PhD Type

The University is looking for a Marie Curie Early Stage Researcher To carry out research relevant to the EU funded research project (NeuTouch - https://www.neutouch.eu ) focussing on understanding the neural coding of touch as enabling technology for prosthetics and robotics.
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