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Biotechnology (natural) PhD Projects, Programs & Scholarships

We have 60 Biotechnology (natural) PhD Projects, Programs & Scholarships

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  Novel Natural Products in Algae: an Untapped Resource for New Chemistry, Biochemistry and Bioactivity
  Dr E O'Neill
Application Deadline: 1 March 2020

Funding Type

PhD Type

Algae are a very wide range of organisms that are found all over the planet, able to take the energy from the sun and convert CO2 into all the molecules they need to live.
  Genome mining of novel antimicrobial natural products from new bacterial strains
  Dr H Deng, Prof M Jaspars
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  Discovery of novel pharmaceuticals from marine and desert microorganisms
  Prof M Jaspars, Dr R Ebel
Applications accepted all year round

Funding Type

PhD Type

Microorganisms from extreme environments such as the deep seas, cold seas and hyper arid deserts have been shown to produce a range of complex natural products with high biological activity.
  Elucidating plant alkaloid biosynthesis
  Dr B R Lichman, Dr W Unsworth
Application Deadline: 30 June 2020

Funding Type

PhD Type

Plants are capable of forming complex natural products from simple starting materials. Many of these natural products are bioactive, but access is limited as they are difficult to synthesise using organic chemistry and are present in small quantities in the natural source.
  (BBSRC DTP) Discovery, development and application of novel amine and imine biocatalysts for the synthesis of natural products, their analogues and other privileged motifs
  Dr R Whitehead, Prof N Turner, Prof P Barran
Application Deadline: 31 January 2020

Funding Type

PhD Type

This is a cross-disciplinary project, which combines the complementary research expertise of Professor Nick Turner (biocatalysis), Professor Perdita Barran (mass spectrometry) and Dr Roger Whitehead (organic synthesis/biological chemistry).
  (A*STAR) Engineering pathways to next generation antibiotics
  Prof J Micklefield, Dr A Green
Application Deadline: 31 January 2020

Funding Type

PhD Type

The provision of new antibiotics to combat antimicrobial resistance (AMR) and to treat neglected tropical diseases (NTD), which are problematic in the developing world, is a major global challenge.
  (BBSRC DTP) Discovery and Editing Pathways to New Antibiotics
  Prof J Micklefield, Prof D Leys, Dr A Green
Application Deadline: 31 January 2020

Funding Type

PhD Type

There is an urgent need for new antibiotics. The majority of antibiotics that are used to treat infectious diseases today are small molecules produced by microorganisms, called natural products, or derivatives thereof.
  Fully-funded PhD positions in several natural sciences & engineering disciplines

Funding Type

PhD Type

Join an internationally renowned scientific community with the Hector FellowPhD program. PhD students benefit not only from the experience of the program, but also from the network of Hector Fellows.
  Evaluation of natural plant based botanicals as alternative to therapeutic antibiotics
  Dr C Situ
Applications accepted all year round

Funding Type

PhD Type

It has become widely recognised that antimicrobial resistance (AMR) is one of the biggest health threats that mankind faces, encompassing huge health and economic burdens on governments and societies in every region of the globe.
  (BBSRC DTP CASE) Design of a light-driven biocatalyst
  Prof D Leys, Dr S Hay
Application Deadline: 31 January 2020

Funding Type

PhD Type

Illumination is able to unlock a wide range of photochemical reactions, but light is rarely used by living organisms. In fact, to date only three light dependent enzymes have been described in detail.
  Designing a microbial platform for the biorefinery of Sargassum (brown algae) golden tides
  Dr T Tonon, Prof S J McQueen-Mason
Application Deadline: 5 January 2020

Funding Type

PhD Type

Oceans are the largest untapped growth opportunity for biomass. As an. illustration, golden tides due to the massive beaching of floating Sargassum.
  QUADRAT DTP: Development of artificial reefs: design, scientific monitoring, environment impact and management in North/Irish Seas
  Prof F Kuepper, Dr M Sonebi
Application Deadline: 22 January 2020

Funding Type

PhD Type

With the population growth along coastlines the demand of infrastructure for various societal needs such as transportation (ports), energies (pipelines…
  In Silico design and chemoenzymatic synthesis of bioactive cyclic and stapled peptides
  Dr W Houssen, Dr S Dall'Angelo, Dr G S Bewick
Application Deadline: 24 January 2020

Funding Type

PhD Type

Cyclic and modified cyclic peptides are very appealing scaffolds especially as therapeutics with several examples reach the clinic e.g.
  (BBSRC DTP CASE) Exploitation of P450 BM3 variants for production of valuable drug metabolites
  Prof A Munro, Prof D Leys
Application Deadline: 31 January 2020

Funding Type

PhD Type

The US Food and Drug Administration (FDA) have recommended that human drug metabolites (as well as their parent drugs) should be subject to testing for safety/toxicity.
  (BBSRC DTP) Solubilising Insoluble Proteins using Self-Assembling Supramolecular Structures
  Dr I Riddell, Dr L Wong, Prof P Barran
Application Deadline: 31 January 2020

Funding Type

PhD Type

Protein insolubility is a common problem for researchers working with isolated proteins that, due to hydrophobic patches on their surface, misfold and/or aggregate outside of their natural environment.
  Engineering de novo microscopic ecologies to monitor and dissect disease spread
  Dr T Gorochowski, Dr S English
Application Deadline: 6 January 2020

Funding Type

PhD Type

Understanding what regulates the spread of diseases in space and time is critical if we are to combat them effectively.
  Link between antibiotic production and bacterial development (KELEMENGU20SCIO)
  Dr G Kelemen, Prof A Ganesan
Application Deadline: 30 January 2020

Funding Type

PhD Type

The widespread emergence of antibiotic resistant pathogens has led to an urgent need for a better understanding of antibiotic production in these organisms to underpin the discovery and development of new antimicrobial agents.
  Synthetic Virology: Development of gene delivery vectors/synthetic vaccines
  Research Group: Astbury Centre for Structural Molecular Biology
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

There is worldwide interest in exploiting our modern understanding of genomics to target gene expression therapeutically via a variety of mechanisms, such as transgene insertion and CRISPR-Cas gene editing.
  Designing and evolving plastic-degrading enzymes for new function
  Dr B Lichtenstein, Prof J McGeehan, Dr S Robson
Application Deadline: 7 February 2020

Funding Type

PhD Type

Applications are invited for a fully-funded four year PhD studentship to commence in October 2020. The PhD will be based at the University’s Centre for Enzyme Innovation (CEI), and will be supervised by Dr Bruce Lichtenstein, Prof.
  Exploring the genome architecture of plastic-degrading bacteria
  Dr S Robson, Dr J.E.M Watts
Application Deadline: 7 February 2020

Funding Type

PhD Type

Applications are invited for a fully-funded four year PhD studentship to commence in October 2020. The PhD will be based at the University’s Centre for Enzyme Innovation (CEI), and will be supervised by Dr Sam Robson and Dr Joy Watts.
  Chemo-enzymatic Synthesis and Potential Applications of Novel Heterocyclic Alkaloids
  Dr H Deng, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  Developing an enzymatic toolbox to make complex modified peptides
  Prof M Jaspars, Dr W Houssen, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

The pharmaceutical industry has identified a major gap in its portfolio. On the one hand, they are excellent at discovering small molecules that act via a lock and key type mechanism.
  EASTBIO: Dehalogenases from the brown algal genome model Ectocarpus siliculosus
  Prof F Kuepper, Dr H Deng, Prof M Jaspars
Application Deadline: 5 January 2020

Funding Type

PhD Type

Supervisors. Professor Frithjof Kuepper (University of Aberdeen). http://www.abdn.ac.uk/oceanlab/research/frithjof-kuepper.php. Dr Hai Deng (University of Aberdeen).
  A 3D in vitro model of wound healing incorporating skin, nerves and immune cells
  Dr A M Rajnicek, Prof H M Wilson
Applications accepted all year round

Funding Type

PhD Type

Diabetes, paralysis, being bed ridden and other conditions can result in chronic wounds that fail to heal, with significant personal consequences for patients and an annual cost of £4.5-5.1 billion annually (Guest et al., 2015) to the National Health Service.
  EASTBIO: Understanding the pathogenesis of life-threatening Burkholderia cenocepacia infections using blocking antibodies and novel chemistry scaffolds to untangle complex aspects of AMR
  Prof A Porter, Dr S Palliyil, Prof M Jaspars
Application Deadline: 5 January 2020

Funding Type

PhD Type

Supervisors. Professor Andy Porter (University of Aberdeen). https://www.abdn.ac.uk/people/a.porter. Dr Soumya Palliyil (University of Aberdeen).
  Movement-science inspired development of upper-limb prostheses for young children
  Dr S Watt, Dr K Valyear
Application Deadline: 1 March 2020

Funding Type

PhD Type

Project rationale and description. Growing up without a hand poses unique and difficult challenges. Prosthesis provision for infants and young children is extremely limited, and the basic-science principles that inform how children learn to use prosthetic devices are largely unknown.
  Mapping Antarctic marine microbial diversity and identification of bioactive molecules with an emphasis on antimicrobials
  Prof M Clark, Dr K Howell
Application Deadline: 7 January 2020

Funding Type

PhD Type

Antimicrobial resistance (AMR) is one of the most serious threats to global human health, resulting in 700,000 deaths per year. This figure is currently rising year on year.
  Development of a Spores-on-a-Chip Microfluidic Chemostat for Exploring the Responsiveness of Bacterial Spore Communities
  Dr C Stanley
Application Deadline: 1 February 2020

Funding Type

PhD Type

The Stanley Lab will be moving to the Department of Bioengineering at Imperial College London, the UK’s leading Bioengineering department, and has a fully funded PhD studentship to develop Spores-on-a-Chip microfluidic technology to gain a deeper insight into bacterial spore germination.
  Investigation of a probiotic strain of Lactobacillus plantarum 2025 and the development of novel antibacterials
  Prof A Karlyshev
Applications accepted all year round

Funding Type

PhD Type

Background. The rise of multidrug resistant forms of microbial pathogens imposes a serious problem to public health worldwide. The rapid spread of antimicrobial resistance is associated with misuse of conventional antibiotics.
  Interactions underlying physiological function of Microtubule Associated Protein 2c
  Prof L Zidek, Dr J Hritz
Application Deadline: 20 February 2020

Funding Type

PhD Type

Microtubule associated protein 2c (MAP2c) is a key factor regulating microtubule dynamics in developing brain neurons, and an example of an intrinsically disordered proteins with an important physiological function and detectable structure-function relationship.
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