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Biotechnology (transgenic) PhD Projects, Programs & Scholarships

We have 8 Biotechnology (transgenic) PhD Projects, Programs & Scholarships

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  Multimerisation of ELAV/Hu proteins – a key mechanism ensuring specificity for RNA recognition in health and disease
  Dr M Soller, Dr T Knowles
Applications accepted all year round

Funding Type

PhD Type

Aims. Determine the structure of the ELAV dodecameric complex bound to target RNA by cryoEM and functionally probe interaction interfaces in vitro and in vivo in transgenic Drosophila models for neurodegeneration and cancer.
  EASTBIO: Resistance in Crop Roots: Functional Analysis of the H2-Meditated Response to Nematodes
  Dr S Mantelin, Prof J Jones
Application Deadline: 5 January 2020

Funding Type

PhD Type

Resistance genes provide plants with protection against a range of pathogens. Despite their use in crop breeding programmes, our knowledge of how plant resistance genes function is still sketchy and mainly based on studies in leaves rather than roots.
  Reprogramming stomatal behaviour to reduce water use in crops
  Prof L Sweetlove, Prof R G Ratcliffe
Application Deadline: 24 January 2020

Funding Type

PhD Type

Future food security will depend on developing crop plants that are as efficient as possible in their utilisation of finite resources such as water.
  Development of gene therapies for muscular dystrophies
  Dr L Popplewell
Applications accepted all year round

Funding Type

PhD Type

The activities in the Popplewell lab focus on the development of pre-clinical gene therapies for neuromuscular diseases, in particular muscular dystrophies based on gene replacement, endonuclease-mediated gene editing, antisense oligonucleotide (AO)-induced exon skipping and gene sliencing.
  Regulation of autophagy in human embryonic stem cells and its therapeutic application in induced pluripotent stem cell-based disease models
  Dr S Sarkar
Applications accepted all year round

Funding Type

PhD Type

Project background. Regulation of proteostasis is critical for maintaining tissue homeostasis. Autophagy, a major intracellular degradation pathway essential for cellular and energy homeostasis, functions in the clearance of aggregation-prone proteins and damaged organelles.
  Precision Medicine DTP - Illuminating roles of Wnt/b-Catenin signalling in nonalcoholic fatty liver disease (NAFLD)
  Research Group: MRC Centre for Regenerative Medicine
  Dr K Kaji, Dr S Tomlinson, Dr J Fallowfield
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Non-Alcoholic Fatty Liver Disease (NAFLD) caused by a high fat diet (HFD) is a growing major public health problem world-wide.
  EASTBIO Targeted genome editing to replace nuclear-encoded Rubisco in rice
  Research Group: Institute of Molecular Plant Sciences
  Dr A McCormick
Application Deadline: 5 January 2020

Funding Type

PhD Type

Second Supervisor. Dr Elizabete Carmo-Silva, Lancaster University. Overview. Ribulose 1,5-bisphosphate carboxylase/ oxygenase (Rubisco) is the driving force behind CO2 assimilation in all plants.
  Understanding how altered GABA signalling in the brain’s master clock contributes to circadian rhythm disruption in Alzheimer’s disease. PhD in Medical Studies (MRC GW4 BioMed DTP)
  Dr M Belle
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr Mino Belle, Institute of Biomedical and Clinical Science, Medical School, University of Exeter. Dr James Hodge, Faculty of Life Sciences, University of Bristol.
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