University of Leeds Bioinformatics PhD Projects, Programmes & Scholarships for Self-funded Students

We have 21 University of Leeds Bioinformatics PhD Projects, Programmes & Scholarships for Self-funded Students

NIHR Leeds BRC: The role of target organs in initiation of autoimmunity in systemic lupus erythematosus

University of Leeds Faculty of Medicine and Health

Autoimmune diseases such as SLE have traditionally been understood to result from aberrant haematopoietic adaptive immune system that targets normal tissues such as the skin and joints. Read more

Supervisor: Dr E Vital

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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NIHR Leeds BRC: The microbiome and the promotion of bowel cancer: The key to understanding causation and prevention of this important disease

University of Leeds Faculty of Medicine and Health

Bowel cancer is the second commonest cause of cancer death in the UK and affects 1.9 million people annually worldwide. Its cause is still unknown but recent work by Wood et al. Read more

Supervisors: Dr K Marks, Dr H Wood, Dr N West, Prof P Quirke

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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NIHR Leeds BRC: Pre-clinical evaluation of novel regenerative medicine strategies for knee osteoarthritis

University of Leeds Faculty of Medicine and Health

Historically, articular cartilage was considered incapable of spontaneous repair. However, biomechanical correction in osteoarthritis (OA) using high tibial osteotomy or joint distraction demonstrated the remarkable joint to regeneration by “merely” correcting joint alignment. Read more

Supervisors: Prof H Pandit, Prof D McGonagle

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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NIHR Leeds BRC: Multimodal predictive modelling of outcome in patients with gastrointestinal cancer

University of Leeds Faculty of Medicine and Health

Worldwide, cancer of the upper (oesophagus, stomach) and lower gastrointestinal (colon and rectum) tract is newly diagnosed in 3.6 million patients every year and 2.2 million patients die from this disease every year. Read more

Supervisors: Dr H Grabsch, Dr N West, Dr D Magee

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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NIHR Leeds BRC: Exploring the impact of 'hidden' antibiotic resistance

University of Leeds Faculty of Medicine and Health

Antibiotics make possible the treatment of life-threatening infections and have added over a decade to average human lifespan. Read more

Supervisors: Prof A O'Neill, Dr K Davies, Dr J Sandoe

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia susceptibility using model systems

University of Leeds Faculty of Medicine and Health

Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more

Supervisors: Prof P Hopkins, Dr M-A Shaw, Dr C Diggle

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

University of Leeds Faculty of Medicine and Health

The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more

Supervisors: Dr G Mavria, Dr S Bell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic reprogramming of immune cells; novel mechanism for drug resistance in leukaemia

University of Leeds Faculty of Medicine and Health

Under pathogenic challenges, cells of the haematopoietic system become epigenetically reprogrammed and establish immune memory. Read more

Supervisor: Dr P Laslo

Year round applications PhD Research Project Self-Funded PhD Students Only

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Translational Medicine: Understanding the mechanism(s) of resistance to EPA to personalise therapy and improve outcome

University of Leeds Faculty of Medicine and Health

Advanced colorectal cancer (CRC) is the UK’s second most lethal cancer, with limited treatment options for unresectable metastatic tumours. Read more

Supervisors: Dr MA Volpato, Prof M Hull

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer Biology: The role of Wnt signaling in glioblastoma therapeutic resistance

University of Leeds Faculty of Medicine and Health

Glioblastoma is a deadly brain tumour treated with surgery, radiotherapy and chemotherapy with patient survival of 6-15 months. Read more

Supervisors: Dr G Mavria, Dr S Bell, Dr C Toomes

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 21 University of Leeds Bioinformatics PhD Projects, Programmes & Scholarships for Self-funded Students

University of Leeds Bioinformatics PhD Projects, Programmes & Scholarships for Self-funded Students

We have 21 University of Leeds Bioinformatics PhD Projects, Programmes & Scholarships for Self-funded Students

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