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University of Birmingham Biotechnology PhD Projects, Programs & Scholarships

We have 9 University of Birmingham Biotechnology PhD Projects, Programs & Scholarships

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Showing 1 to 9 of 9
  Regulation of autophagy in human embryonic stem cells and its therapeutic application in induced pluripotent stem cell-based disease models
  Dr S Sarkar
Applications accepted all year round

Funding Type

PhD Type

Project background. Regulation of proteostasis is critical for maintaining tissue homeostasis. Autophagy, a major intracellular degradation pathway essential for cellular and energy homeostasis, functions in the clearance of aggregation-prone proteins and damaged organelles.
  Creating “super” regulatory T cells to combat rejection, GVHD and autoimmunity through retroviral gene manipulation
  Dr N Jones, Dr S Lee
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Foxp3+CD25+CD4+ regulatory T cells (Treg) have been shown to be essential for the induction of tolerance to foreign organ transplants in experimental models.
  Development of novel artificial intelligence algorithms for network wide metabolic flux analysis with stable isotope tracers
  Dr C Ludwig, Dr S He
Applications accepted all year round

Funding Type

PhD Type

The efficient function of the metabolic network in eukaryotic cells relies on its separation into a number of closely-linked but metabolically distinct compartments.
  Repairing DNA Damage in Response to BRAF Mutation
  Dr C McCabe, Prof G Stewart
Applications accepted all year round

Funding Type

PhD Type

We are the leading thyroid cancer research group in the UK; we work on other neoplasias as well, including breast and head and neck etc.
  Vitamin D and immunometabolism
  Prof M Hewison, Dr S Dimeloe
Applications accepted all year round

Funding Type

PhD Type

Vitamin D has potent anti-inflammatory and antibacterial immune effects.
  Eukaryotic gene expression: understanding the role of UPF1 in global mRNA processing and amyotrophic lateral sclerosis (ALS)
  Dr S Brogna
Applications accepted all year round

Funding Type

PhD Type

This project’s specific objective is to study the molecular role(s) that the RNA helicase UPF1 plays in RNA processing. UPF1 is a key player in nonsense-mediated mRNA decay (NMD), it is universally conserved in eukaryotes and is essential to the development of many organisms [1].
  Integrated mathematical modelling and experimental research into interactions between microorganisms
  Dr J U Kreft
Applications accepted all year round

Funding Type

PhD Type

Our group aims to combine theoretical & experimental approaches to understand major problems in the ecology and evolution of microbes.
  mRNA epigenetics: Charaterization of a novel layer of gene regulation for essential brain functions
  Research Group: BBSRC MIBTP
  Dr M Soller, Dr PG Grzechnik
Applications accepted all year round

Funding Type

PhD Type

For over 40 years we know about modified nucleotides in mRNA, but the functions for these essential modifications are largely elusive.
  Multimerisation of ELAV/Hu proteins – a key mechanism ensuring specificity for RNA recognition in health and disease
  Dr M Soller, Dr T Knowles
Applications accepted all year round

Funding Type

PhD Type

Aims. Determine the structure of the ELAV dodecameric complex bound to target RNA by cryoEM and functionally probe interaction interfaces in vitro and in vivo in transgenic Drosophila models for neurodegeneration and cancer.
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