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Biochemistry PhD Projects, Programs & Scholarships in Birmingham

We have 47 Biochemistry PhD Projects, Programs & Scholarships in Birmingham

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  Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam
  Dr M Soller
Applications accepted all year round
Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response.
  Multimerisation of ELAV/Hu proteins – a key mechanism ensuring specificity for RNA recognition in health and disease
  Dr M Soller, Dr T Knowles
Applications accepted all year round
Aims. Determine the structure of the ELAV dodecameric complex bound to target RNA by cryoEM and functionally probe interaction interfaces in vitro and in vivo in transgenic Drosophila models for neurodegeneration and cancer.
  mRNA epigenetics: Charaterization of a novel layer of gene regulation for essential brain functions
  Research Group: BBSRC MIBTP
  Dr M Soller, Dr PG Grzechnik
Applications accepted all year round
For over 40 years we know about modified nucleotides in mRNA, but the functions for these essential modifications are largely elusive.
  BBSRC MIBTP - Identification of pathways deregulating neuronal ELAV/Hu RNA binding proteins and alternative splicing in neurodegeneration
  Research Group: BBSRC MIBTP
  Dr M Soller, Dr M Tomlinson
Applications accepted all year round
ELAV/Hu proteins comprise a family of highly conserved neuronal RNA binding proteins important for the development of the nervous system and for neuronal functions.
  Integrating omics, imaging and informatics to develop physiology-based kinetic (PBK) models for perturbation biology in an invertebrate model species
  Prof M Viant, Dr B Campos, Dr C Rivetti, Dr I Sorrell
Application Deadline: 4 February 2019
This exciting 4-year BBSRC iCASE PhD opportunity bridges the University of Birmingham’s (*) metabolomics team and Unilever’s Safety and Environmental Assurance Centre (SEAC), both having state-of-the-art facilities and renowned research programmes, thereby creating an excellent environment for this challenging yet impactful research project.
  De novo design of a new generation of catalysts based on rhodium coiled coils
  Dr A Peacock
Applications accepted all year round
This PhD project will generate a new class of miniature metalloenzymes based on rhodium coiled coils, which bring together the power of enzymatic catalysis, as provided by the coiled coil miniature protein-type scaffold, and small molecule rhodium catalysis.
  Discovering new drugs for Mycobacterium abscessus infections in children
  Dr J Cox
Application Deadline: 27 January 2019
Applications are invited from candidates to undertake a PhD in the field of microbiology.
  Exercise, vitamin D and immune function: to explore the effects of exercise on vitamin D metabolism in humans
  Dr G Wallis, Prof M Hewison
Applications accepted all year round
Exercise is well known to be of benefit for health, including enhancing the immune system. How exercise works to enhance health is not completely known.
  Investigating Potential Applications of Functional DNA-based Materials and Sensors
  Prof J Tucker
Applications accepted all year round
This PhD project falls into the areas of supramolecular chemistry, chemical biology and DNA nanotechnology and involves the preparation and study of DNA-based materials and sensors.
  Regulation of autophagy in human embryonic stem cells and its therapeutic application in induced pluripotent stem cell-based disease models
  Dr S Sarkar
Applications accepted all year round
Project background. Regulation of proteostasis is critical for maintaining tissue homeostasis. Autophagy, a major intracellular degradation pathway essential for cellular and energy homeostasis, functions in the clearance of aggregation-prone proteins and damaged organelles.
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