Imperial College London Featured PhD Programmes
Imperial College London Featured PhD Programmes
De Montfort University Featured PhD Programmes

Cell Biology / Development PhD Projects, Programs & Scholarships in Birmingham

We have 39 Cell Biology / Development PhD Projects, Programs & Scholarships in Birmingham

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Birmingham  United Kingdom

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We have 39 Cell Biology / Development PhD Projects, Programs & Scholarships in Birmingham

Molecular mechanisms in receptor signalling

About the Project. Understanding the molecular mechanisms of receptor signalling and regulation is detrimental for developing novel diagnostic and therapeutic tools in biomedical research e.g., in the context of thrombo-inflammation. Read more

Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more

Targeting steroid metabolism to block colorectal cancer proliferation

Our group is a world leader in targeting specific aspects of steroid metabolism to block cancer growth. Our research has been instrumental in the successful pre-clinical and clinical development of various novel anti-cancer compounds. Read more

Determining novel molecular regulators of necrosis controlling premature cell death

Necrosis, a form of premature cell death, is frequently caused by excessive insults such as trauma, infection and toxins. It has been implicated in many human diseases including cancer, neurodegenerative disorders and inflammatory diseases. Read more

Dissecting the role of novel haematopoietic factors in development and disease

Blood is made up of different cell types with different functions, such as carrying oxygen (red blood cells), help with wound healing (platelets) and fighting infections (white blood cells). Read more

Signalling DNA replication faults.

Errors in DNA replication are key to the development of cancer. Problems in DNA replication are signalled to the cell through a cascade of post-translational modifications, best understood of which is phosphorylation. Read more

Investigating the role of lysine methylation in the DNA damage response.

Our genomic DNA is under constant attack from DNA damaging agents, which are a continuing threat to genomic integrity. Defective resolution of DNA damage underlies several human diseases, including neurological abnormalities and developmental disorders as well as cancer. Read more

Novel anti-pathogen regulatory mechanisms driven by Human Guanylate Binding Proteins

Human GBPs are a family of seven ~65kDa GTPases whose expression is upregulated by IFNg, for example during an infection. All mammalian GBPs contain a GTPase domain and a C-terminal helical region. Read more

Development of a novel calcium-based hydraulic sealer

Root canal therapy is necessary when the dental pulp is damaged irreversibly and has to be removed. The loss of the dental pulp creates a dead space inside the tooth which is colonized by bacteria. Read more

Identification of novel regulators of pancreatic beta-cell identity

Diabetes is the largest epidemic in human history that affects 1 in 12 adults worldwide. Due to our modern lifestyle, it is one of the few diseases where the incidence is set to rise dramatically, with projections putting 650 million people at risk by 2040. Read more

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