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Genetics PhD Projects, Programs & Scholarships in Birmingham

We have 14 Genetics PhD Projects, Programs & Scholarships in Birmingham

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Birmingham  United Kingdom

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We have 14 Genetics PhD Projects, Programs & Scholarships in Birmingham

Identification of novel regulators of pancreatic beta-cell identity

Diabetes is the largest epidemic in human history that affects 1 in 12 adults worldwide. Due to our modern lifestyle, it is one of the few diseases where the incidence is set to rise dramatically, with projections putting 650 million people at risk by 2040. Read more

Exploiting rare polymorphisms, structural variation, and germline-somatic mutation interactions to explain missing heritability in cancer development.

Understanding cancer heritability has an enormous impact on disease prevention, early detection and tailored treatment. GWAS based on single nucleotide polymorphisms only explain a modest fraction (2-15%) of heritable variation in cancer risk (McCarroll, 2008). Read more

Determining novel molecular regulators of necrosis controlling premature cell death

Necrosis, a form of premature cell death, is frequently caused by excessive insults such as trauma, infection and toxins. It has been implicated in many human diseases including cancer, neurodegenerative disorders and inflammatory diseases. Read more

Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more

Dissecting mechanisms that control adult stem cells in health, disease, and ageing

Adult organs are maintained by specialised stem cells that persist throughout life thanks to their ability to make exact copies of themselves, all the time retaining the ability to on demand produce the differentiated component cells of the tissue of which they are a part. Read more

Dissecting the role of novel haematopoietic factors in development and disease

Blood is made up of different cell types with different functions, such as carrying oxygen (red blood cells), help with wound healing (platelets) and fighting infections (white blood cells). Read more

Investigating the impact of lysine methylation in neuronal DNA repair

Our genomic DNA is under constant attack from DNA damaging agents, which are a continuing threat to genomic integrity. Defective resolution of DNA damage underlies several human diseases, including neurological abnormalities and developmental disorders as well as cancer. Read more

Investigating the role of lysine methylation in the DNA damage response.

Our genomic DNA is under constant attack from DNA damaging agents, which are a continuing threat to genomic integrity. Defective resolution of DNA damage underlies several human diseases, including neurological abnormalities and developmental disorders as well as cancer. Read more
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