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Genetics PhD Projects, Programs & Scholarships in Birmingham

We have 27 Genetics PhD Projects, Programs & Scholarships in Birmingham

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  Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam
  Dr M Soller
Application Deadline: 20 January 2019
Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response.
  Multimerisation of ELAV/Hu proteins – a key mechanism ensuring specificity for RNA recognition in health and disease
  Dr M Soller, Dr T Knowles
Application Deadline: 20 January 2019
Aims. Determine the structure of the ELAV dodecameric complex bound to target RNA by cryoEM and functionally probe interaction interfaces in vitro and in vivo in transgenic Drosophila models for neurodegeneration and cancer.
  Dissecting the interplay between cardiomyocytes and fibroblasts using human stem cell models of disease
  Dr D Pavlovic, Prof C Denning
Application Deadline: 20 January 2019
Applications are invited for a fully-funded PhD Studentship starting in October 2019, under the guidance of Dr Davor Pavlovic (University of Birmingham) and Prof Chris Denning (University of Nottingham).
  Promoter regulation heterogeneity and stratification of colorectal cancer organoids
  Prof F Mueller, Dr D J Stekel, Dr A Beggs
Application Deadline: 20 January 2019
Developing tumours are composed of a mixture of clonal subpopulations, containing distinct patterns of mutations leading to distinct transcriptome features.
  Arrhythmogenic potential of titin truncating variants in atrial and ventricular cardiomyocytes
  Dr K Gehmlich, Prof C Denning, Prof P Kirchhof
Application Deadline: 20 January 2019
Aims. The aim of this project is to understand to role of titin truncating variants (TTNtv) in the development of atrial and ventricular arrhythmias.
  Cancer Research UK Birmingham Centre - Clinical and Non-Clinical PhD Fellowships
Studentships available. 3 (2 Non-Clinical and 1 Clinical PhD Fellowship). Funding - Non-clinical. £140,000 over four years, including fees, laboratory expenses (£13,500 pa), and stipend (£19,000 pa).
  Regulation of autophagy in human embryonic stem cells and its therapeutic application in induced pluripotent stem cell-based disease models
  Dr S Sarkar
Applications accepted all year round
Project background. Regulation of proteostasis is critical for maintaining tissue homeostasis. Autophagy, a major intracellular degradation pathway essential for cellular and energy homeostasis, functions in the clearance of aggregation-prone proteins and damaged organelles.
  Methods for quantitative genetic analyses in autotetraploids
  Prof Z Luo
Applications accepted all year round
Methods for quantitative genetic analysis have been well established in almost all important diploid plants and animal including humans, and have served as essential tools for dissecting the genetic architectures underlying agronomically, evolutionarily and medically interesting quantitative and complex traits.
  The genetic basis of adaptive evolution
  Dr L Leach, Prof J B Brown, Prof J Colbourne, Dr L Orsini
Application Deadline: 21 January 2019
A unique study system (the micro-crustacean Daphnia) is used to identify the mechanisms of adaptation to environmental change. These include epigenetics enabling phenotypic plasticity that may precede and inform the genetic fixation of adaptive traits.
  Elucidating the transmission and persistence of antimicrobial resistance genes in the Thames watershed
  Dr J U Kreft
Application Deadline: 21 January 2019
The widespread use of antibiotics in human and veterinary medicine and as growth promoters in agriculture has not only selected for resistance genes but also for plasmids carrying them.
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