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Molecular Biology PhD Projects, Programs & Scholarships in Birmingham

We have 36 Molecular Biology PhD Projects, Programs & Scholarships in Birmingham

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Birmingham  United Kingdom

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We have 36 Molecular Biology PhD Projects, Programs & Scholarships in Birmingham

Molecular mechanisms in receptor signalling

About the Project. Understanding the molecular mechanisms of receptor signalling and regulation is detrimental for developing novel diagnostic and therapeutic tools in biomedical research e.g., in the context of thrombo-inflammation. Read more

Determining novel molecular regulators of necrosis controlling premature cell death

Necrosis, a form of premature cell death, is frequently caused by excessive insults such as trauma, infection and toxins. It has been implicated in many human diseases including cancer, neurodegenerative disorders and inflammatory diseases. Read more

Identification of novel regulators of pancreatic beta-cell identity

Diabetes is the largest epidemic in human history that affects 1 in 12 adults worldwide. Due to our modern lifestyle, it is one of the few diseases where the incidence is set to rise dramatically, with projections putting 650 million people at risk by 2040. Read more

Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more

The Role of LIM Domain Only Proteins in Neuroblastoma

Person Specification. An Upper Second Class Honours Degree (or equivalent) in a relevant study or Master’s degree is expected. Prior experience in cell and molecular biology is an advantage. Read more

Signalling DNA replication faults.

Errors in DNA replication are key to the development of cancer. Problems in DNA replication are signalled to the cell through a cascade of post-translational modifications, best understood of which is phosphorylation. Read more

Investigating the impact of lysine methylation in neuronal DNA repair

Our genomic DNA is under constant attack from DNA damaging agents, which are a continuing threat to genomic integrity. Defective resolution of DNA damage underlies several human diseases, including neurological abnormalities and developmental disorders as well as cancer. Read more

Investigating the role of lysine methylation in the DNA damage response.

Our genomic DNA is under constant attack from DNA damaging agents, which are a continuing threat to genomic integrity. Defective resolution of DNA damage underlies several human diseases, including neurological abnormalities and developmental disorders as well as cancer. Read more

Polo-like kinase inhibitors for targeted treatment of adrenocortical carcinoma

Dr Ronchi is a clinician scientist and an Endocrinologist with long-standing expertise in endocrine tumors. Her research field mostly focuses on molecular markers involved in the pathogenesis and prognosis of adrenocortical carcinoma (ACC), a rare orphan disease with several unmet needs. Read more

The role of glucocorticoid desulfation in chronic inflammatory disease pathophysiology

Chronic inflammatory diseases (CIDs) are a common group of highly disabling immune conditions leading to persistent inflammation and tissue-specific manifestations, such as ulcerative colitis and arthritis. Read more

Developing Novel Therapies to Prevent Atherosclerosis

Background. There is intense interest in identifying the genes that predispose to the development of atherosclerosis. We recently carried out an expression analysis of human tissue using microarrays that identified several candidate genes. Read more

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