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Biochemistry PhD Projects, Programs & Scholarships in Bradford

We have 38 Biochemistry PhD Projects, Programs & Scholarships in Bradford

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We have 38 Biochemistry PhD Projects, Programs & Scholarships in Bradford

Investigation of antagonism of multiple RGD-binding integrins as a therapeutic strategy in advanced head and neck cancer

  Research Group: Institute of Cancer Therapeutics
Background. The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more

Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas

  Research Group: School of Molecular and Cellular Biology
V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves the breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas. Read more

Development of a personalized therapy for pulmonary arterial hypertension (PAH)

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Therapeutic resolution of coronavirus (COVID-19) diseases by natural products

  Research Group: Pharmacology and Experimental Therapeutics
Coronavirus now labelled as Covid-19 has become a global pandemic affecting around 200 countries. Currently neither any cure nor any vaccine for Covid-19 has been established. Read more

Therapeutic resolution of pulmonary arterial hypertension (PAH) by natural products

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Artificial cells with biochemical clocks: oscillatory enzyme reactions in confinement

  Research Group: School of Chemistry
Artificial cells are engineered materials that mimic one or more of the functions of living biological cells. Oscillating chemical processes are common within living organisms to control a variety of essential processes, including the metabolism of sugars and the release of hormones. Read more

Phenotypic characterisation of red and white blood cells from patients with Type 2 diabetes mellitus

  Research Group: Chemistry and Biosciences
The prevalence of Type 2 diabetes (T2DM) is escalating at an alarming rate, with almost 10% of the UK population suffering from T2DM or in a pre-diabetic state. Read more

Clinical: Gastroesophageal reflux in respiratory disease: pathogenic role and improved management

Gastroesophageal reflux disease (GERD) is a condition in which stomach contents, such as food and acid pass into the gullet/oesophagus causing heartburn. GERD is very common in patients with lung disease, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). Read more

Cell Biology: Exploring the mitotic functions of ASPM in human brain size regulation

The increase in relative brain size is one of the most striking events in human evolution. To determine how human brain size is normally regulated we have investigated the cause of autosomal recessive primary microcephaly (MCPH), a congenital disorder of reduced brain size and associated mental retardation. Read more

Targeting protein acetylation to reduce microglia activation in neurodegenerative disorders

Recently, inhibitors of histone deacetylase enzymes (HDACs) have been identified as having potential therapeutic value for a range of neuronal disorders including Alzheimer’s disease, dementia and stroke [1, 2]. Read more

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