Research Group:
Astbury Centre for Structural Molecular Biology
Dr E Paci, Prof W B Turnbull
Application Deadline:
30 September 2019
The ability of protein molecules to stick to cells is crucial for life and disease. The project is based on a novel concept to design adhesive molecules based on multivalence and entropic stabilisation.
Regular patterns, such as stripes, squares and hexagons, are ubiquitous in nature, and their formation and stability are governed by the intricate and complex interactions of symmetry and nonlinearity.
Plastic contamination is a great ecological disaster facing modern society; a burden overwhelmingly heaped on the least economically developed countries.
Gestational Diabetes is a temporary condition diagnosed at 24-28 weeks gestation, where the body is unable to maintain normal blood glucose levels due to insulin resistance during pregnancy.
Human inherited retinal diseases (IRDs) result from mutations in over 250 different genes, many of them implicated by the Leeds Vision Research Group (eg Panagiotou et al 2017, AJHG 100:960-968; El-Asrag et al 2015, 96:948-54).
Amelogenesis is the process of enamel formation and is essential for the development of functional teeth. Amelogenesis imperfecta (AI) is a failure of that process.
Schizophrenia is a chronic mental health condition affecting 1% of human populations, with symptoms that include visual and auditory hallucinations, delusions and disordered thought, leading to disruption of the sense of self.
Human inherited retinal dystrophies (IRDs) result from mutations in over 200 different genes, many of them first implicated by the Leeds Vision Research Group (eg Panagiotou E et al 2017, AJHG 100:960-968; El-Asrag M et al 2015, 96:948-54).