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We have 27 Bioinformatics PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Bradford

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Biological Sciences

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Bradford  United Kingdom

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Bioinformatics PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Bradford

We have 27 Bioinformatics PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships in Bradford

A Bioinformatics PhD would provide you with the opportunity to work on an extended, in-detail project through the analysis of large sets of data. Bioinformatics programmes tend to be mostly ‘dry’ work with limited (if any) time in the laboratory conducting experiments. Since the focus is analysis of data, the choice of projects spans many subjects from analysing bacterial evolution, to modelling the spread of disease.

What’s it like to do a PhD in Bioinformatics?

As a Bioinformatics PhD student, you’ll work with the latest software and become proficient with programming in R, Python and MATLAB. You’ll also gain extensive experience with techniques from statistics and data science, all of which will allow you to analyse data effectively.

Some typical research topics in Bioinformatics include:

  • Genetic mapping
  • Population dynamics
  • Epidemiological modelling (modelling disease spread)
  • Improving diagnosis through the development of an algorithm
  • Using omic technology to study a disease state
  • Modelling and predicting evolution

Most Bioinformatics programmes advertised projects with full funding attached. These projects have a pre-determined aim, but you can alter the project along the way to suit your interests.

Compared to other Biology programmes, there is more opportunity of proposing a project, though this remains uncommon. While the majority are advertised projects, some doctoral training programmes offer bioinformatics projects in a given area and leave you to propose the specifics of the project.

In a normal day you’ll be writing programmes to identify new features in the data, analysing results using statistics and data science methods and discussing your project with your supervisor and colleagues.

At the end of the three or four years you’ll complete a thesis of around 60,000 words, which will contribute to your field and you’ll defend it during your viva exam.

Entry requirements

The entry requirements for most Bioinformatics PhD programmes involve a Masters in a related subject including Maths, Biological Science, Computer Science, or Software Engineering, with at least a Merit or Distinction. If English isn’t your first language, you’ll also need to show that you have the right level of language proficiency.

PhD in Bioinformatics funding options

The Research Council responsible for funding Bioinformatics PhDs in the UK is the Biotechnology and Biological Sciences Research Council (BBSRC). They provide fully-funded studentships including a stipend for living costs, a consumables budget for bench fees and a tuition fee waiver. Students don’t apply directly to the BBSRC, you apply for advertised projects with this funding attached.

It’s uncommon for Bioinformatics PhD students to be ‘self-funded’ due to the additional bench fees. However, if you were planning to fund yourself it might be achievable (depending on your project) through the UK government’s PhD loan and part-time work.

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Integrated omics approach to psychiatric disorders

  Research Group: Chemistry and Biosciences
In psychiatry, the selection of antipsychotics and antidepressants is led by a trial-and-error approach. The prescribing of these medications is complicated by sub-optimal efficacy and high rates of adverse drug reactions (ADRs). Read more

Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas

  Research Group: School of Molecular and Cellular Biology
V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves the breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas. Read more

Genetics: Investigating the molecular basis of optic nerve degeneration in glaucoma to try and develop a personalized medicine strategy for treatment

The optic nerve is a special sensory nerve that transmits visual impulses from the retina to the brain. Primary Open Angle Glaucoma (POAG) is a chronic, progressive optic neuropathy of multifactorial origin that affects 1 in 10 elderly individuals. Read more

Genetics: Genetic studies of developmental eye disorders to investigate genotype-phenotype correlations

Developmental eye defects that affect the front of the eye give rise to a spectrum of congenital ocular phenotypes that affect the cornea, lens, iris, trabecular meshwork or the globe itself. Read more

Discovery and Development of Biocatalytic Solutions to Mitigate Microplastic Pollution

  Research Group: Chemistry and Biosciences
Plastic contamination is a great ecological disaster facing modern society; a burden overwhelmingly heaped on the least economically developed countries. Read more

Responsible AI for Health and Social Care

The increasing adoption of Artificial Intelligence (AI) technologies that could impact humanity raises increasing concerns from general public, industry and regulatory bodies. Read more

The Biosynthesis of Neurotransmitter Molecules: An evolutionary perspective

We research the evolutionary origins of the biosynthesis of biochemicals that are important to human health and wellbeing. Neurotransmission is in many ways the defining characteristic of animals, which are multicellular organisms that can sense changes in their environment and react quickly. Read more

Cancer: Epigenetic therapy using microbubble-mediated drug delivery for colorectal cancer

The project is an interdisciplinary, pre-clinical study that aims to investigate the response of human tumour cells to treatment with epigenetic inhibitors (including DNA methyltransferase inhibitors, HDAC inhibitors and/or vitamin C), as a potential combination therapy for colorectal cancer (CRC). Read more

Genetics: Unravelling the Norrin/beta-catenin signaling pathway and its role in retinal angiogenesis and blindness

Our previous work on the genetic analysis of individuals with the inherited retinal disease Familial Exudative Vitreoretinopathy (FEVR), has helped identify a new angiogenesis pathway, the Norrin/beta-catenin pathway. Read more

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