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We have 23 Bioinformatics PhD Projects, Programmes & Scholarships in Bradford
Bioinformatics PhD Projects, Programmes & Scholarships in Bradford
We have 23 Bioinformatics PhD Projects, Programmes & Scholarships in Bradford
Clinical: Adherence with Cancer Treatment in Adolescents and Young Adults
Adherence with therapy is a significant clinical problem in young people, for many reasons. The scale of this has never been quantified in a population-based setting. Read more
Genetics: Unravelling the Norrin/beta-catenin signaling pathway and its role in retinal angiogenesis and blindness
Our previous work on the genetic analysis of individuals with the inherited retinal disease Familial Exudative Vitreoretinopathy (FEVR), has helped identify a new angiogenesis pathway, the Norrin/beta-catenin pathway. Read more
Immunotherapy: Killing Cancer using Dead Virus
It is now accepted that our immune systems can hold the key to treating otherwise incurable cancers. So-called “immunotherapy” is an increasingly common method of treating tumours, leading to impressive increases in patient responses. . Read more
Haematology: Oncogenic reprogramming of immune cells
Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory. Read more
Clinical Gastroenterology: The regulation of GDH expression in Clostridioides difficile
Clostridioides difficile infection (CDI), the most common cause of infective antibiotic-associated diarrhea in the western world, is diagnosed by a combination of tests that firstly detect the organism, then the toxins that it produces (Planche 2013). Read more
Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile
Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more
Cancer: Repurposing drugs as new treatments for breast cancer
Breast cancer (BC) is the most common cancer, with over 1 million new cases diagnosed worldwide each year. For some types of BC, hormonal treatments have been very effective but one particular BC subtype, triple negative breast cancer (TNBC), is highly aggressive and lacks a targeted therapy. Read more
Cancer: Inhibiting cell metabolism to enhance tumour cell death
All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more
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